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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LAMA5
Full Name:
Laminin subunit alpha-5
Alias:
Laminin alpha 5; Laminin, alpha 5
Type:
Cytoskeletal protein
Mass (Da):
399799
Number AA:
3695
UniProt ID:
O15230
International Prot ID:
IPI00783665
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005578
GO:0005604
Uniprot
OncoNet
Molecular Function:
GO:0005102
GO:0005198
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0009987
GO:0022610
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
E
E
A
G
G
G
F
S
L
H
P
P
Y
F
N
Site 2
Y49
G
F
S
L
H
P
P
Y
F
N
L
A
E
G
A
Site 3
S61
E
G
A
R
I
A
A
S
A
T
C
G
E
E
A
Site 4
S73
E
E
A
P
A
R
G
S
P
R
P
T
E
D
L
Site 5
T77
A
R
G
S
P
R
P
T
E
D
L
Y
C
K
L
Site 6
Y81
P
R
P
T
E
D
L
Y
C
K
L
V
G
G
P
Site 7
T97
A
G
G
D
P
N
Q
T
I
R
G
Q
Y
C
D
Site 8
Y102
N
Q
T
I
R
G
Q
Y
C
D
I
C
T
A
A
Site 9
S118
S
N
K
A
H
P
A
S
N
A
I
D
G
T
E
Site 10
S130
G
T
E
R
W
W
Q
S
P
P
L
S
R
G
L
Site 11
S134
W
W
Q
S
P
P
L
S
R
G
L
E
Y
N
E
Site 12
T145
E
Y
N
E
V
N
V
T
L
D
L
G
Q
V
F
Site 13
S175
D
L
W
V
L
E
R
S
M
D
F
G
R
T
Y
Site 14
T181
R
S
M
D
F
G
R
T
Y
Q
P
W
Q
F
F
Site 15
Y182
S
M
D
F
G
R
T
Y
Q
P
W
Q
F
F
A
Site 16
S191
P
W
Q
F
F
A
S
S
K
R
D
C
L
E
R
Site 17
T203
L
E
R
F
G
P
Q
T
L
E
R
I
T
R
D
Site 18
T208
P
Q
T
L
E
R
I
T
R
D
D
A
A
I
C
Site 19
T216
R
D
D
A
A
I
C
T
T
E
Y
S
R
I
V
Site 20
S233
E
N
G
E
I
V
V
S
L
V
N
G
R
P
G
Site 21
S245
R
P
G
A
M
N
F
S
Y
S
P
L
L
R
E
Site 22
Y246
P
G
A
M
N
F
S
Y
S
P
L
L
R
E
F
Site 23
S247
G
A
M
N
F
S
Y
S
P
L
L
R
E
F
T
Site 24
T254
S
P
L
L
R
E
F
T
K
A
T
N
V
R
L
Site 25
T266
V
R
L
R
F
L
R
T
N
T
L
L
G
H
L
Site 26
T282
G
K
A
L
R
D
P
T
V
T
R
R
Y
Y
Y
Site 27
T284
A
L
R
D
P
T
V
T
R
R
Y
Y
Y
S
I
Site 28
Y287
D
P
T
V
T
R
R
Y
Y
Y
S
I
K
D
I
Site 29
Y288
P
T
V
T
R
R
Y
Y
Y
S
I
K
D
I
S
Site 30
Y289
T
V
T
R
R
Y
Y
Y
S
I
K
D
I
S
I
Site 31
S290
V
T
R
R
Y
Y
Y
S
I
K
D
I
S
I
G
Site 32
T315
A
C
D
A
K
D
P
T
D
P
F
R
L
Q
C
Site 33
Y369
Y
G
H
A
T
D
C
Y
Y
D
P
E
V
D
R
Site 34
Y370
G
H
A
T
D
C
Y
Y
D
P
E
V
D
R
R
Site 35
S380
E
V
D
R
R
R
A
S
Q
S
L
D
G
T
Y
Site 36
S382
D
R
R
R
A
S
Q
S
L
D
G
T
Y
Q
G
Site 37
T386
A
S
Q
S
L
D
G
T
Y
Q
G
G
G
V
C
Site 38
Y387
S
Q
S
L
D
G
T
Y
Q
G
G
G
V
C
I
Site 39
Y413
E
R
C
L
P
G
F
Y
R
S
P
N
H
P
L
Site 40
S415
C
L
P
G
F
Y
R
S
P
N
H
P
L
D
S
Site 41
S422
S
P
N
H
P
L
D
S
P
H
V
C
R
R
C
Site 42
T436
C
N
C
E
S
D
F
T
D
G
T
C
E
D
L
Site 43
T439
E
S
D
F
T
D
G
T
C
E
D
L
T
G
R
Site 44
T444
D
G
T
C
E
D
L
T
G
R
C
Y
C
R
P
Site 45
Y448
E
D
L
T
G
R
C
Y
C
R
P
N
F
S
G
Site 46
S470
E
G
F
T
G
F
P
S
C
Y
P
T
P
S
S
Site 47
Y472
F
T
G
F
P
S
C
Y
P
T
P
S
S
S
N
Site 48
T474
G
F
P
S
C
Y
P
T
P
S
S
S
N
D
T
Site 49
S476
P
S
C
Y
P
T
P
S
S
S
N
D
T
R
E
Site 50
S477
S
C
Y
P
T
P
S
S
S
N
D
T
R
E
Q
Site 51
S478
C
Y
P
T
P
S
S
S
N
D
T
R
E
Q
V
Site 52
T481
T
P
S
S
S
N
D
T
R
E
Q
V
L
P
A
Site 53
S545
C
Q
P
C
Q
C
S
S
P
G
V
A
D
D
R
Site 54
T594
C
G
C
S
P
A
G
T
L
P
E
G
C
D
E
Site 55
Y656
L
C
R
C
R
P
G
Y
T
G
T
A
C
Q
E
Site 56
S697
D
P
R
S
G
Q
C
S
C
R
P
R
V
T
G
Site 57
T703
C
S
C
R
P
R
V
T
G
L
R
C
D
T
C
Site 58
Y715
D
T
C
V
P
G
A
Y
N
F
P
Y
C
E
A
Site 59
Y719
P
G
A
Y
N
F
P
Y
C
E
A
G
S
C
H
Site 60
S766
K
P
G
F
W
G
L
S
P
S
N
P
E
G
C
Site 61
S768
G
F
W
G
L
S
P
S
N
P
E
G
C
T
R
Site 62
S777
P
E
G
C
T
R
C
S
C
D
L
R
G
T
L
Site 63
Y823
F
G
L
D
Q
A
D
Y
F
G
C
R
S
C
R
Site 64
S840
I
G
G
A
L
G
Q
S
C
E
P
R
T
G
V
Site 65
T854
V
C
R
C
R
P
N
T
Q
G
P
T
C
S
E
Site 66
S860
N
T
Q
G
P
T
C
S
E
P
A
R
D
H
Y
Site 67
Y867
S
E
P
A
R
D
H
Y
L
P
D
L
H
H
L
Site 68
T883
L
E
L
E
E
A
A
T
P
E
G
H
A
V
R
Site 69
Y906
E
N
F
S
W
R
G
Y
A
Q
M
A
P
V
Q
Site 70
S943
N
R
G
A
M
S
V
S
G
R
V
S
V
R
E
Site 71
S947
M
S
V
S
G
R
V
S
V
R
E
E
G
R
S
Site 72
S954
S
V
R
E
E
G
R
S
A
T
C
A
N
C
T
Site 73
T956
R
E
E
G
R
S
A
T
C
A
N
C
T
A
Q
Site 74
T979
S
T
E
P
A
F
I
T
V
P
Q
R
G
F
G
Site 75
T1032
L
R
V
T
E
A
C
T
Y
R
P
S
A
Q
Q
Site 76
Y1033
R
V
T
E
A
C
T
Y
R
P
S
A
Q
Q
S
Site 77
S1036
E
A
C
T
Y
R
P
S
A
Q
Q
S
G
D
N
Site 78
S1040
Y
R
P
S
A
Q
Q
S
G
D
N
C
L
L
Y
Site 79
Y1047
S
G
D
N
C
L
L
Y
T
H
L
P
L
D
G
Site 80
S1070
A
L
C
R
Q
D
N
S
L
P
R
P
C
P
T
Site 81
T1077
S
L
P
R
P
C
P
T
E
Q
L
S
P
S
H
Site 82
S1081
P
C
P
T
E
Q
L
S
P
S
H
P
P
L
I
Site 83
S1083
P
T
E
Q
L
S
P
S
H
P
P
L
I
T
C
Site 84
T1089
P
S
H
P
P
L
I
T
C
T
G
S
D
V
D
Site 85
T1130
E
V
G
V
A
V
H
T
P
Q
R
A
P
Q
Q
Site 86
T1149
L
H
P
C
L
Y
S
T
L
C
R
G
T
A
R
Site 87
T1154
Y
S
T
L
C
R
G
T
A
R
D
T
Q
D
H
Site 88
T1158
C
R
G
T
A
R
D
T
Q
D
H
L
A
V
F
Site 89
S1172
F
H
L
D
S
E
A
S
V
R
L
T
A
E
Q
Site 90
T1176
S
E
A
S
V
R
L
T
A
E
Q
A
R
F
F
Site 91
S1196
L
V
P
I
E
E
F
S
P
E
F
V
E
P
R
Site 92
S1205
E
F
V
E
P
R
V
S
C
I
S
S
H
G
A
Site 93
S1208
E
P
R
V
S
C
I
S
S
H
G
A
F
G
P
Site 94
S1209
P
R
V
S
C
I
S
S
H
G
A
F
G
P
N
Site 95
S1217
H
G
A
F
G
P
N
S
A
A
C
L
P
S
R
Site 96
S1223
N
S
A
A
C
L
P
S
R
F
P
K
P
P
Q
Site 97
T1249
L
P
P
G
L
P
L
T
H
A
Q
D
L
T
P
Site 98
T1255
L
T
H
A
Q
D
L
T
P
A
M
S
P
A
G
Site 99
S1259
Q
D
L
T
P
A
M
S
P
A
G
P
R
P
R
Site 100
T1269
G
P
R
P
R
P
P
T
A
V
D
P
D
A
E
Site 101
T1278
V
D
P
D
A
E
P
T
L
L
R
E
P
Q
A
Site 102
Y1306
Y
A
F
L
L
H
G
Y
Q
P
A
H
P
T
F
Site 103
T1360
D
V
T
H
S
E
L
T
V
T
V
R
V
P
K
Site 104
T1362
T
H
S
E
L
T
V
T
V
R
V
P
K
G
R
Site 105
S1385
V
V
P
E
N
V
Y
S
F
G
Y
L
R
E
E
Site 106
Y1388
E
N
V
Y
S
F
G
Y
L
R
E
E
P
L
D
Site 107
S1397
R
E
E
P
L
D
K
S
Y
D
F
I
S
H
C
Site 108
Y1398
E
E
P
L
D
K
S
Y
D
F
I
S
H
C
A
Site 109
Y1409
S
H
C
A
A
Q
G
Y
H
I
S
P
S
S
S
Site 110
S1412
A
A
Q
G
Y
H
I
S
P
S
S
S
S
L
F
Site 111
S1414
Q
G
Y
H
I
S
P
S
S
S
S
L
F
C
R
Site 112
S1415
G
Y
H
I
S
P
S
S
S
S
L
F
C
R
N
Site 113
S1416
Y
H
I
S
P
S
S
S
S
L
F
C
R
N
A
Site 114
S1417
H
I
S
P
S
S
S
S
L
F
C
R
N
A
A
Site 115
S1428
R
N
A
A
A
S
L
S
L
F
Y
N
N
G
A
Site 116
T1446
G
C
H
E
V
G
A
T
G
P
T
C
E
P
F
Site 117
T1449
E
V
G
A
T
G
P
T
C
E
P
F
G
G
Q
Site 118
T1542
I
Q
E
L
T
D
P
T
C
D
T
D
S
G
Q
Site 119
T1545
L
T
D
P
T
C
D
T
D
S
G
Q
C
K
C
Site 120
T1563
V
T
G
R
R
C
D
T
C
S
P
G
F
H
G
Site 121
S1565
G
R
R
C
D
T
C
S
P
G
F
H
G
Y
P
Site 122
S1611
G
P
K
C
D
Q
C
S
L
G
T
F
S
L
D
Site 123
S1616
Q
C
S
L
G
T
F
S
L
D
A
A
N
P
K
Site 124
S1639
G
A
T
E
R
C
R
S
S
S
Y
T
R
Q
E
Site 125
S1640
A
T
E
R
C
R
S
S
S
Y
T
R
Q
E
F
Site 126
S1641
T
E
R
C
R
S
S
S
Y
T
R
Q
E
F
V
Site 127
Y1642
E
R
C
R
S
S
S
Y
T
R
Q
E
F
V
D
Site 128
T1643
R
C
R
S
S
S
Y
T
R
Q
E
F
V
D
M
Site 129
T1658
E
G
W
V
L
L
S
T
D
R
Q
V
V
P
H
Site 130
Y1693
P
E
A
F
P
E
L
Y
W
Q
A
P
P
S
Y
Site 131
S1699
L
Y
W
Q
A
P
P
S
Y
L
G
D
R
V
S
Site 132
Y1700
Y
W
Q
A
P
P
S
Y
L
G
D
R
V
S
S
Site 133
S1706
S
Y
L
G
D
R
V
S
S
Y
G
G
T
L
R
Site 134
S1707
Y
L
G
D
R
V
S
S
Y
G
G
T
L
R
Y
Site 135
Y1708
L
G
D
R
V
S
S
Y
G
G
T
L
R
Y
E
Site 136
T1711
R
V
S
S
Y
G
G
T
L
R
Y
E
L
H
S
Site 137
Y1714
S
Y
G
G
T
L
R
Y
E
L
H
S
E
T
Q
Site 138
S1718
T
L
R
Y
E
L
H
S
E
T
Q
R
G
D
V
Site 139
T1720
R
Y
E
L
H
S
E
T
Q
R
G
D
V
F
V
Site 140
T1745
Q
G
N
Q
M
S
I
T
F
L
E
P
A
Y
P
Site 141
Y1751
I
T
F
L
E
P
A
Y
P
T
P
G
H
V
H
Site 142
T1753
F
L
E
P
A
Y
P
T
P
G
H
V
H
R
G
Site 143
T1772
V
E
G
N
F
R
H
T
E
T
R
N
T
V
S
Site 144
T1777
R
H
T
E
T
R
N
T
V
S
R
E
E
L
M
Site 145
S1804
A
L
F
S
Q
I
S
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A
V
F
L
R
R
V
Site 146
S1836
E
L
C
L
C
P
A
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Y
R
G
D
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C
Q
Site 147
Y1837
L
C
L
C
P
A
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D
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C
Q
E
Site 148
S1841
P
A
S
Y
R
G
D
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C
Q
E
C
A
P
G
Site 149
S1877
S
D
R
C
L
P
G
S
G
V
C
V
D
C
Q
Site 150
S1901
R
C
Q
A
G
F
M
S
S
R
D
D
P
S
A
Site 151
S1902
C
Q
A
G
F
M
S
S
R
D
D
P
S
A
P
Site 152
S1907
M
S
S
R
D
D
P
S
A
P
C
V
S
C
P
Site 153
Y1943
Q
C
L
C
K
P
G
Y
A
G
A
S
C
E
R
Site 154
S1947
K
P
G
Y
A
G
A
S
C
E
R
C
A
P
G
Site 155
S1965
N
P
L
V
L
G
S
S
C
Q
P
C
D
C
S
Site 156
S1982
G
D
P
N
L
L
F
S
D
C
D
P
L
T
G
Site 157
T1998
C
R
G
C
L
R
H
T
T
G
P
R
C
E
I
Site 158
T1999
R
G
C
L
R
H
T
T
G
P
R
C
E
I
C
Site 159
S2079
C
G
P
A
A
E
G
S
E
C
H
P
Q
S
G
Site 160
Y2106
C
R
E
C
A
P
G
Y
W
G
L
P
E
Q
G
Site 161
T2128
G
G
R
C
D
P
H
T
G
R
C
N
C
P
P
Site 162
T2144
L
S
G
E
R
C
D
T
C
S
Q
Q
H
Q
V
Site 163
S2198
Q
L
R
G
I
N
A
S
S
M
A
W
A
R
L
Site 164
S2199
L
R
G
I
N
A
S
S
M
A
W
A
R
L
H
Site 165
S2211
R
L
H
R
L
N
A
S
I
A
D
L
Q
S
Q
Site 166
S2217
A
S
I
A
D
L
Q
S
Q
L
R
S
P
L
G
Site 167
S2221
D
L
Q
S
Q
L
R
S
P
L
G
P
R
H
E
Site 168
T2229
P
L
G
P
R
H
E
T
A
Q
Q
L
E
V
L
Site 169
T2241
E
V
L
E
Q
Q
S
T
S
L
G
Q
D
A
R
Site 170
S2262
V
G
T
R
D
Q
A
S
Q
L
L
A
G
T
E
Site 171
T2288
A
I
R
A
V
D
R
T
L
S
E
L
M
S
Q
Site 172
S2290
R
A
V
D
R
T
L
S
E
L
M
S
Q
T
G
Site 173
S2294
R
T
L
S
E
L
M
S
Q
T
G
H
L
G
L
Site 174
S2305
H
L
G
L
A
N
A
S
A
P
S
G
E
Q
L
Site 175
T2315
S
G
E
Q
L
L
R
T
L
A
E
V
E
R
L
Site 176
S2358
R
V
Q
E
Q
L
S
S
L
W
E
E
N
Q
A
Site 177
T2395
L
N
R
A
V
D
A
T
R
E
A
Q
E
L
N
Site 178
S2420
L
Q
R
K
Q
E
L
S
R
D
N
A
T
L
Q
Site 179
T2425
E
L
S
R
D
N
A
T
L
Q
A
T
L
H
A
Site 180
T2466
A
S
L
D
G
A
R
T
P
L
L
Q
R
M
Q
Site 181
T2474
P
L
L
Q
R
M
Q
T
F
S
P
A
G
S
K
Site 182
S2476
L
Q
R
M
Q
T
F
S
P
A
G
S
K
L
R
Site 183
S2480
Q
T
F
S
P
A
G
S
K
L
R
L
V
E
A
Site 184
T2515
D
V
N
Q
D
R
L
T
Q
R
A
I
E
A
S
Site 185
S2522
T
Q
R
A
I
E
A
S
N
A
Y
S
R
I
L
Site 186
S2526
I
E
A
S
N
A
Y
S
R
I
L
Q
A
V
Q
Site 187
T2552
Q
A
D
H
T
W
A
T
V
V
R
Q
G
L
V
Site 188
T2622
Q
A
M
L
A
M
D
T
D
E
T
S
K
K
I
Site 189
S2626
A
M
D
T
D
E
T
S
K
K
I
A
H
A
K
Site 190
T2642
V
A
A
E
A
Q
D
T
A
T
R
V
Q
S
Q
Site 191
T2644
A
E
A
Q
D
T
A
T
R
V
Q
S
Q
L
Q
Site 192
S2648
D
T
A
T
R
V
Q
S
Q
L
Q
A
M
Q
E
Site 193
Y2664
V
E
R
W
Q
G
Q
Y
E
G
L
R
G
Q
D
Site 194
S2682
A
V
L
D
A
G
H
S
V
S
T
L
E
K
T
Site 195
S2684
L
D
A
G
H
S
V
S
T
L
E
K
T
L
P
Site 196
T2689
S
V
S
T
L
E
K
T
L
P
Q
L
L
A
K
Site 197
S2715
A
S
L
A
L
S
A
S
I
G
R
V
R
E
L
Site 198
S2731
A
Q
A
R
G
A
A
S
K
V
K
V
P
M
K
Site 199
T2749
R
S
G
V
Q
L
R
T
P
R
D
L
A
D
L
Site 200
T2777
E
P
E
P
G
Q
G
T
E
D
R
F
V
M
Y
Site 201
T2791
Y
M
G
S
R
Q
A
T
G
D
Y
M
G
V
S
Site 202
Y2794
S
R
Q
A
T
G
D
Y
M
G
V
S
L
R
D
Site 203
S2798
T
G
D
Y
M
G
V
S
L
R
D
K
K
V
H
Site 204
Y2808
D
K
K
V
H
W
V
Y
Q
L
G
E
A
G
P
Site 205
S2819
E
A
G
P
A
V
L
S
I
D
E
D
I
G
E
Site 206
S2832
G
E
Q
F
A
A
V
S
L
D
R
T
L
Q
F
Site 207
T2845
Q
F
G
H
M
S
V
T
V
E
R
Q
M
I
Q
Site 208
T2858
I
Q
E
T
K
G
D
T
V
A
P
G
A
E
G
Site 209
Y2877
R
P
D
D
F
V
F
Y
V
G
G
Y
P
S
T
Site 210
T2886
G
G
Y
P
S
T
F
T
P
P
P
L
L
R
F
Site 211
Y2896
P
L
L
R
F
P
G
Y
R
G
C
I
E
M
D
Site 212
T2904
R
G
C
I
E
M
D
T
L
N
E
E
V
V
S
Site 213
S2911
T
L
N
E
E
V
V
S
L
Y
N
F
E
R
T
Site 214
Y2913
N
E
E
V
V
S
L
Y
N
F
E
R
T
F
Q
Site 215
T2923
E
R
T
F
Q
L
D
T
A
V
D
R
P
C
A
Site 216
S2932
V
D
R
P
C
A
R
S
K
S
T
G
D
P
W
Site 217
S2934
R
P
C
A
R
S
K
S
T
G
D
P
W
L
T
Site 218
T2941
S
T
G
D
P
W
L
T
D
G
S
Y
L
D
G
Site 219
S2944
D
P
W
L
T
D
G
S
Y
L
D
G
T
G
F
Site 220
Y2945
P
W
L
T
D
G
S
Y
L
D
G
T
G
F
A
Site 221
T2949
D
G
S
Y
L
D
G
T
G
F
A
R
I
S
F
Site 222
S2955
G
T
G
F
A
R
I
S
F
D
S
Q
I
S
T
Site 223
S2958
F
A
R
I
S
F
D
S
Q
I
S
T
T
K
R
Site 224
T2962
S
F
D
S
Q
I
S
T
T
K
R
F
E
Q
E
Site 225
T3021
L
Q
P
P
P
P
L
T
S
A
S
K
A
I
Q
Site 226
S3022
Q
P
P
P
P
L
T
S
A
S
K
A
I
Q
V
Site 227
T3047
L
V
R
V
E
R
A
T
V
Y
S
V
E
Q
D
Site 228
Y3049
R
V
E
R
A
T
V
Y
S
V
E
Q
D
N
D
Site 229
S3050
V
E
R
A
T
V
Y
S
V
E
Q
D
N
D
L
Site 230
S3076
P
P
D
Q
L
P
P
S
L
R
W
L
F
P
T
Site 231
T3083
S
L
R
W
L
F
P
T
G
G
S
V
R
G
C
Site 232
Y3100
G
I
K
A
L
G
K
Y
V
D
L
K
R
L
N
Site 233
S3155
Y
S
G
F
G
F
H
S
A
Q
D
S
A
L
L
Site 234
S3159
G
F
H
S
A
Q
D
S
A
L
L
Y
Y
R
A
Site 235
Y3163
A
Q
D
S
A
L
L
Y
Y
R
A
S
P
D
G
Site 236
S3175
P
D
G
L
C
Q
V
S
L
Q
Q
G
R
V
S
Site 237
S3182
S
L
Q
Q
G
R
V
S
L
Q
L
L
R
T
E
Site 238
T3188
V
S
L
Q
L
L
R
T
E
V
K
T
Q
A
G
Site 239
T3192
L
L
R
T
E
V
K
T
Q
A
G
F
A
D
G
Site 240
Y3216
N
A
T
G
V
W
L
Y
V
D
D
Q
L
Q
Q
Site 241
T3254
G
G
L
P
E
S
G
T
I
Y
N
F
S
G
C
Site 242
S3285
D
L
Q
Q
N
L
G
S
V
N
V
S
T
G
C
Site 243
T3300
A
P
A
L
Q
A
Q
T
P
G
L
G
P
R
G
Site 244
T3311
G
P
R
G
L
Q
A
T
A
R
K
A
S
R
R
Site 245
S3316
Q
A
T
A
R
K
A
S
R
R
S
R
Q
P
A
Site 246
S3319
A
R
K
A
S
R
R
S
R
Q
P
A
R
H
P
Site 247
T3336
M
L
P
P
H
L
R
T
T
R
D
S
Y
Q
F
Site 248
T3337
L
P
P
H
L
R
T
T
R
D
S
Y
Q
F
G
Site 249
S3340
H
L
R
T
T
R
D
S
Y
Q
F
G
G
S
L
Site 250
Y3341
L
R
T
T
R
D
S
Y
Q
F
G
G
S
L
S
Site 251
S3346
D
S
Y
Q
F
G
G
S
L
S
S
H
L
E
F
Site 252
S3348
Y
Q
F
G
G
S
L
S
S
H
L
E
F
V
G
Site 253
S3365
A
R
H
R
N
W
P
S
L
S
M
H
V
L
P
Site 254
S3367
H
R
N
W
P
S
L
S
M
H
V
L
P
R
S
Site 255
T3382
S
R
G
L
L
L
F
T
A
R
L
R
P
G
S
Site 256
S3391
R
L
R
P
G
S
P
S
L
A
L
F
L
S
N
Site 257
T3410
A
Q
M
E
G
L
G
T
R
L
R
A
Q
S
R
Site 258
S3416
G
T
R
L
R
A
Q
S
R
Q
R
S
R
P
G
Site 259
S3420
R
A
Q
S
R
Q
R
S
R
P
G
R
W
H
K
Site 260
T3441
K
N
R
I
L
L
V
T
D
G
A
R
A
W
S
Site 261
S3448
T
D
G
A
R
A
W
S
Q
E
G
P
H
R
Q
Site 262
T3466
A
E
H
P
Q
P
H
T
L
F
V
G
G
L
P
Site 263
S3475
F
V
G
G
L
P
A
S
S
H
S
S
K
L
P
Site 264
S3476
V
G
G
L
P
A
S
S
H
S
S
K
L
P
V
Site 265
S3479
L
P
A
S
S
H
S
S
K
L
P
V
T
V
G
Site 266
T3566
F
H
L
G
Q
A
R
T
P
P
Y
L
Q
L
Q
Site 267
Y3569
G
Q
A
R
T
P
P
Y
L
Q
L
Q
V
T
E
Site 268
T3575
P
Y
L
Q
L
Q
V
T
E
K
Q
V
L
L
R
Site 269
S3591
D
D
G
A
G
E
F
S
T
S
V
T
R
P
S
Site 270
T3592
D
G
A
G
E
F
S
T
S
V
T
R
P
S
V
Site 271
S3593
G
A
G
E
F
S
T
S
V
T
R
P
S
V
L
Site 272
T3595
G
E
F
S
T
S
V
T
R
P
S
V
L
C
D
Site 273
S3598
S
T
S
V
T
R
P
S
V
L
C
D
G
Q
W
Site 274
S3613
H
R
L
A
V
M
K
S
G
N
V
L
R
L
E
Site 275
S3625
R
L
E
V
D
A
Q
S
N
H
T
V
G
P
L
Site 276
S3673
R
R
L
A
V
N
R
S
P
V
A
M
T
R
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation