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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC22A2
Full Name:
Solute carrier family 22 member 2
Alias:
Oct2; S22a2; Slc22a2; Solute carrier family 22 (organic cation transporter) member 2; Solute carrier family 22 (organic cation transporter), member 2
Type:
Membrane fraction, Membrane, Integral plasma membrane protein
Mass (Da):
62565
Number AA:
555
UniProt ID:
O15244
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0005326
GO:0015101
PhosphoSite+
KinaseNET
Biological Process:
GO:0007589
GO:0015695
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T46
G
I
V
F
L
G
F
T
P
D
H
R
C
R
S
Site 2
S53
T
P
D
H
R
C
R
S
P
G
V
A
E
L
S
Site 3
S60
S
P
G
V
A
E
L
S
L
R
C
G
W
S
P
Site 4
S66
L
S
L
R
C
G
W
S
P
A
E
E
L
N
Y
Site 5
Y73
S
P
A
E
E
L
N
Y
T
V
P
G
P
G
P
Site 6
T74
P
A
E
E
L
N
Y
T
V
P
G
P
G
P
A
Site 7
S85
P
G
P
A
G
E
A
S
P
R
Q
C
R
R
Y
Site 8
Y92
S
P
R
Q
C
R
R
Y
E
V
D
W
N
Q
S
Site 9
T112
D
P
L
A
S
L
D
T
N
R
S
R
L
P
L
Site 10
S115
A
S
L
D
T
N
R
S
R
L
P
L
G
P
C
Site 11
Y128
P
C
R
D
G
W
V
Y
E
T
P
G
S
S
I
Site 12
T130
R
D
G
W
V
Y
E
T
P
G
S
S
I
V
T
Site 13
S133
W
V
Y
E
T
P
G
S
S
I
V
T
E
F
N
Site 14
Y200
L
M
A
I
S
P
T
Y
T
W
M
L
I
F
R
Site 15
Y233
T
E
F
V
G
R
R
Y
R
R
T
V
G
I
F
Site 16
T236
V
G
R
R
Y
R
R
T
V
G
I
F
Y
Q
V
Site 17
Y241
R
R
T
V
G
I
F
Y
Q
V
A
Y
T
V
G
Site 18
S286
Y
Y
W
C
I
P
E
S
P
R
W
L
I
S
Q
Site 19
S292
E
S
P
R
W
L
I
S
Q
N
K
N
A
E
A
Site 20
S313
I
A
K
K
N
G
K
S
L
P
A
S
L
Q
R
Site 21
S317
N
G
K
S
L
P
A
S
L
Q
R
L
R
L
E
Site 22
S334
T
G
K
K
L
N
P
S
F
L
D
L
V
R
T
Site 23
T341
S
F
L
D
L
V
R
T
P
Q
I
R
K
H
T
Site 24
Y405
I
D
R
I
G
R
R
Y
P
W
A
A
S
N
M
Site 25
S471
N
L
G
V
H
I
C
S
S
M
C
D
I
G
G
Site 26
T489
P
F
L
V
Y
R
L
T
N
I
W
L
E
L
P
Site 27
T517
L
V
L
L
L
P
E
T
K
G
K
A
L
P
E
Site 28
T525
K
G
K
A
L
P
E
T
I
E
E
A
E
N
M
Site 29
Y544
K
N
K
E
K
M
I
Y
L
Q
V
Q
K
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation