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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC22A1
Full Name:
Solute carrier family 22 member 1
Alias:
Organic cation transporter 1
Type:
Mass (Da):
61188
Number AA:
554
UniProt ID:
O15245
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0015101
GO:0005515
GO:0031402
PhosphoSite+
KinaseNET
Biological Process:
GO:0015695
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
T
P
D
H
H
C
Q
S
P
G
V
A
E
L
S
Site 2
S59
S
P
G
V
A
E
L
S
Q
R
C
G
W
S
P
Site 3
S65
L
S
Q
R
C
G
W
S
P
A
E
E
L
N
Y
Site 4
Y72
S
P
A
E
E
L
N
Y
T
V
P
G
L
G
P
Site 5
T73
P
A
E
E
L
N
Y
T
V
P
G
L
G
P
A
Site 6
Y91
F
L
G
Q
C
R
R
Y
E
V
D
W
N
Q
S
Site 7
S108
S
C
V
D
P
L
A
S
L
A
T
N
R
S
H
Site 8
T111
D
P
L
A
S
L
A
T
N
R
S
H
L
P
L
Site 9
S114
A
S
L
A
T
N
R
S
H
L
P
L
G
P
C
Site 10
Y127
P
C
Q
D
G
W
V
Y
D
T
P
G
S
S
I
Site 11
T129
Q
D
G
W
V
Y
D
T
P
G
S
S
I
V
T
Site 12
S213
R
L
L
Q
G
L
V
S
K
G
N
W
M
A
G
Site 13
T235
V
G
S
G
S
R
R
T
V
A
I
M
Y
Q
M
Site 14
S285
Y
Y
W
C
V
P
E
S
P
R
W
L
L
S
Q
Site 15
S291
E
S
P
R
W
L
L
S
Q
K
R
N
T
E
A
Site 16
T296
L
L
S
Q
K
R
N
T
E
A
I
K
I
M
D
Site 17
S321
P
A
D
L
K
M
L
S
L
E
E
D
V
T
E
Site 18
T327
L
S
L
E
E
D
V
T
E
K
L
S
P
S
F
Site 19
S331
E
D
V
T
E
K
L
S
P
S
F
A
D
L
F
Site 20
S333
V
T
E
K
L
S
P
S
F
A
D
L
F
R
T
Site 21
T340
S
F
A
D
L
F
R
T
P
R
L
R
K
R
T
Site 22
T347
T
P
R
L
R
K
R
T
F
I
L
M
Y
L
W
Site 23
Y361
W
F
T
D
S
V
L
Y
Q
G
L
I
L
H
M
Site 24
T524
K
G
V
A
L
P
E
T
M
K
D
A
E
N
L
Site 25
Y543
K
P
K
E
N
T
I
Y
L
K
V
Q
T
S
E
Site 26
T548
T
I
Y
L
K
V
Q
T
S
E
P
S
G
T
_
Site 27
S549
I
Y
L
K
V
Q
T
S
E
P
S
G
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation