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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACOX3
Full Name:
Peroxisomal acyl-coenzyme A oxidase 3
Alias:
Acyl-coenzyme A oxidase 3, peroxisomal; Acyl-Coenzyme A oxidase 3, pristanoyl; Branched-chain acyl-CoA oxidase; BRCACox; BRCOX; EC 1.3.3.6; Peroxisomal, branched-chain acyl-CoA oxidase; PRCOX; Pristanoyl-CoA oxidase
Type:
EC 1.3.3.6; Lipid Metabolism - unsaturated fatty acid biosynthesis; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - fatty acid; Oxidoreductase
Mass (Da):
77629
Number AA:
700
UniProt ID:
O15254
International Prot ID:
IPI00020226
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005777
Uniprot
OncoNet
Molecular Function:
GO:0050660
GO:0003995
GO:0003997
PhosphoSite+
KinaseNET
Biological Process:
GO:0008206
GO:0006635
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
S
T
V
E
G
G
D
T
A
L
L
P
E
F
P
Site 2
Y24
P
R
G
P
L
D
A
Y
R
A
R
A
S
F
S
Site 3
S29
D
A
Y
R
A
R
A
S
F
S
W
K
E
L
A
Site 4
T50
G
M
L
R
F
K
K
T
I
F
S
A
L
E
N
Site 5
S53
R
F
K
K
T
I
F
S
A
L
E
N
D
P
L
Site 6
S64
N
D
P
L
F
A
R
S
P
G
A
D
L
S
L
Site 7
S70
R
S
P
G
A
D
L
S
L
E
K
Y
R
E
L
Site 8
Y74
A
D
L
S
L
E
K
Y
R
E
L
N
F
L
R
Site 9
Y88
R
C
K
R
I
F
E
Y
D
F
L
S
V
E
D
Site 10
S92
I
F
E
Y
D
F
L
S
V
E
D
M
F
K
S
Site 11
S134
V
F
G
S
A
V
Y
S
S
G
S
E
R
H
L
Site 12
S135
F
G
S
A
V
Y
S
S
G
S
E
R
H
L
T
Site 13
S137
S
A
V
Y
S
S
G
S
E
R
H
L
T
Y
I
Site 14
T142
S
G
S
E
R
H
L
T
Y
I
Q
K
I
F
R
Site 15
S162
C
F
A
L
T
E
L
S
H
G
S
N
T
K
A
Site 16
T173
N
T
K
A
I
R
T
T
A
H
Y
D
P
A
T
Site 17
Y176
A
I
R
T
T
A
H
Y
D
P
A
T
E
E
F
Site 18
T180
T
A
H
Y
D
P
A
T
E
E
F
I
I
H
S
Site 19
S187
T
E
E
F
I
I
H
S
P
D
F
E
A
A
K
Site 20
T203
W
V
G
N
M
G
K
T
A
T
H
A
V
V
F
Site 21
T205
G
N
M
G
K
T
A
T
H
A
V
V
F
A
K
Site 22
S272
K
V
R
V
P
R
Q
S
L
L
N
R
M
G
D
Site 23
T281
L
N
R
M
G
D
V
T
P
E
G
T
Y
V
S
Site 24
Y286
D
V
T
P
E
G
T
Y
V
S
P
F
K
D
V
Site 25
S288
T
P
E
G
T
Y
V
S
P
F
K
D
V
R
Q
Site 26
S300
V
R
Q
R
F
G
A
S
L
G
S
L
S
S
G
Site 27
S303
R
F
G
A
S
L
G
S
L
S
S
G
R
V
S
Site 28
T332
I
A
L
R
F
S
A
T
R
R
Q
F
G
P
T
Site 29
T339
T
R
R
Q
F
G
P
T
E
E
E
E
I
P
V
Site 30
Y349
E
E
I
P
V
L
E
Y
P
M
Q
Q
W
R
L
Site 31
S386
E
L
Q
R
G
L
A
S
G
D
R
S
A
R
Q
Site 32
S390
G
L
A
S
G
D
R
S
A
R
Q
A
E
L
G
Site 33
S405
R
E
I
H
A
L
A
S
A
S
K
P
L
A
S
Site 34
Y431
E
A
C
G
G
H
G
Y
L
A
M
N
R
L
G
Site 35
Y450
D
N
D
P
N
C
T
Y
E
G
D
N
N
I
L
Site 36
S481
H
D
G
A
C
F
R
S
P
L
K
S
V
D
F
Site 37
S485
C
F
R
S
P
L
K
S
V
D
F
L
D
A
Y
Site 38
Y492
S
V
D
F
L
D
A
Y
P
G
I
L
D
Q
K
Site 39
S504
D
Q
K
F
E
V
S
S
V
A
D
C
L
D
S
Site 40
Y524
A
Y
K
W
L
V
C
Y
L
L
R
E
T
Y
Q
Site 41
T529
V
C
Y
L
L
R
E
T
Y
Q
K
L
N
Q
E
Site 42
Y530
C
Y
L
L
R
E
T
Y
Q
K
L
N
Q
E
K
Site 43
S541
N
Q
E
K
R
S
G
S
S
D
F
E
A
R
N
Site 44
S553
A
R
N
K
C
Q
V
S
H
G
R
P
L
A
L
Site 45
S579
H
E
H
V
H
Q
P
S
V
P
P
S
L
R
A
Site 46
S583
H
Q
P
S
V
P
P
S
L
R
A
V
L
G
R
Site 47
Y608
S
R
H
A
A
L
L
Y
R
G
G
Y
F
S
G
Site 48
Y612
A
L
L
Y
R
G
G
Y
F
S
G
E
Q
A
G
Site 49
S614
L
Y
R
G
G
Y
F
S
G
E
Q
A
G
E
V
Site 50
S653
P
P
D
F
V
L
D
S
P
I
G
R
A
D
G
Site 51
Y663
G
R
A
D
G
E
L
Y
K
N
L
W
G
A
V
Site 52
S681
S
K
V
L
E
R
A
S
W
W
P
E
F
S
V
Site 53
S695
V
N
K
P
V
I
G
S
L
K
S
K
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation