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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALOX15B
Full Name:
Arachidonate 15-lipoxygenase B
Alias:
15-lipoxygenase 2; 15-LOX-2; EC 1.13.11.33; LX15B
Type:
Enzyme - Lipoxygenase; Cytoplasm
Mass (Da):
75885
Number AA:
676
UniProt ID:
O15296
International Prot ID:
IPI00005781
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0050473
GO:0005506
GO:0016165
PhosphoSite+
KinaseNET
Biological Process:
GO:0006917
GO:0019370
GO:0045786
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
E
F
R
V
R
V
S
T
G
E
A
F
G
A
Site 2
T10
E
F
R
V
R
V
S
T
G
E
A
F
G
A
G
Site 3
S33
I
V
G
T
R
G
E
S
P
P
L
P
L
D
N
Site 4
T95
F
C
R
W
F
Q
L
T
P
P
R
G
G
H
L
Site 5
T115
Q
W
L
E
G
A
G
T
L
V
L
Q
E
G
T
Site 6
T166
P
H
C
L
D
E
K
T
V
E
D
L
E
L
N
Site 7
S177
L
E
L
N
I
K
Y
S
T
A
K
N
A
N
F
Site 8
Y185
T
A
K
N
A
N
F
Y
L
Q
A
G
S
A
F
Site 9
S209
D
R
K
G
L
W
R
S
L
N
E
M
K
R
I
Site 10
T222
R
I
F
N
F
R
R
T
P
A
A
E
H
A
F
Site 11
S240
Q
E
D
A
F
F
A
S
Q
F
L
N
G
L
N
Site 12
S277
S
V
L
G
P
G
T
S
L
Q
A
E
L
E
K
Site 13
S286
Q
A
E
L
E
K
G
S
L
F
L
V
D
H
G
Site 14
T315
Q
F
S
A
A
P
M
T
L
L
Y
Q
S
P
G
Site 15
S334
L
P
L
A
I
Q
L
S
Q
T
P
G
P
N
S
Site 16
T336
L
A
I
Q
L
S
Q
T
P
G
P
N
S
P
I
Site 17
S341
S
Q
T
P
G
P
N
S
P
I
F
L
P
T
D
Site 18
S430
P
G
Q
V
V
D
R
S
T
G
I
G
I
E
G
Site 19
T462
C
L
P
E
D
I
R
T
R
G
V
E
D
I
P
Site 20
Y471
G
V
E
D
I
P
G
Y
Y
Y
R
D
D
G
M
Site 21
Y472
V
E
D
I
P
G
Y
Y
Y
R
D
D
G
M
Q
Site 22
Y473
E
D
I
P
G
Y
Y
Y
R
D
D
G
M
Q
I
Site 23
Y496
S
E
I
I
G
I
Y
Y
P
S
D
E
S
V
Q
Site 24
S498
I
I
G
I
Y
Y
P
S
D
E
S
V
Q
D
D
Site 25
S501
I
Y
Y
P
S
D
E
S
V
Q
D
D
R
E
L
Site 26
S525
K
G
F
L
N
Q
E
S
S
G
I
P
S
S
L
Site 27
S526
G
F
L
N
Q
E
S
S
G
I
P
S
S
L
E
Site 28
S530
Q
E
S
S
G
I
P
S
S
L
E
T
R
E
A
Site 29
S531
E
S
S
G
I
P
S
S
L
E
T
R
E
A
L
Site 30
T534
G
I
P
S
S
L
E
T
R
E
A
L
V
Q
Y
Site 31
S573
W
M
P
N
L
P
P
S
M
Q
L
P
P
P
T
Site 32
S581
M
Q
L
P
P
P
T
S
K
G
L
A
T
C
E
Site 33
S611
I
L
A
L
W
L
L
S
K
E
P
G
D
Q
R
Site 34
Y623
D
Q
R
P
L
G
T
Y
P
D
E
H
F
T
E
Site 35
S636
T
E
E
A
P
R
R
S
I
A
T
F
Q
S
R
Site 36
T639
A
P
R
R
S
I
A
T
F
Q
S
R
L
A
Q
Site 37
S648
Q
S
R
L
A
Q
I
S
R
G
I
Q
E
R
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation