KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GRM6
Full Name:
Metabotropic glutamate receptor 6
Alias:
Type:
Mass (Da):
95468
Number AA:
877
UniProt ID:
O15303
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
G
L
A
R
A
A
G
S
V
R
L
A
G
G
L
Site 2
T40
V
R
L
A
G
G
L
T
L
G
G
L
F
P
V
Site 3
Y74
H
R
L
E
A
M
L
Y
A
L
D
R
V
N
A
Site 4
T98
L
G
A
R
L
L
D
T
C
S
R
D
T
Y
A
Site 5
S100
A
R
L
L
D
T
C
S
R
D
T
Y
A
L
E
Site 6
T103
L
D
T
C
S
R
D
T
Y
A
L
E
Q
A
L
Site 7
Y104
D
T
C
S
R
D
T
Y
A
L
E
Q
A
L
S
Site 8
S176
I
P
Q
I
S
Y
A
S
T
A
P
E
L
S
D
Site 9
T177
P
Q
I
S
Y
A
S
T
A
P
E
L
S
D
S
Site 10
S182
A
S
T
A
P
E
L
S
D
S
T
R
Y
D
F
Site 11
S184
T
A
P
E
L
S
D
S
T
R
Y
D
F
F
S
Site 12
T185
A
P
E
L
S
D
S
T
R
Y
D
F
F
S
R
Site 13
Y187
E
L
S
D
S
T
R
Y
D
F
F
S
R
V
V
Site 14
S191
S
T
R
Y
D
F
F
S
R
V
V
P
P
D
S
Site 15
S198
S
R
V
V
P
P
D
S
Y
Q
A
Q
A
M
V
Site 16
Y199
R
V
V
P
P
D
S
Y
Q
A
Q
A
M
V
D
Site 17
S217
A
L
G
W
N
Y
V
S
T
L
A
S
E
G
N
Site 18
T218
L
G
W
N
Y
V
S
T
L
A
S
E
G
N
Y
Site 19
S221
N
Y
V
S
T
L
A
S
E
G
N
Y
G
E
S
Site 20
Y225
T
L
A
S
E
G
N
Y
G
E
S
G
V
E
A
Site 21
S308
F
L
W
V
G
S
D
S
W
G
A
K
T
S
P
Site 22
T313
S
D
S
W
G
A
K
T
S
P
I
L
S
L
E
Site 23
S314
D
S
W
G
A
K
T
S
P
I
L
S
L
E
D
Site 24
S335
T
I
L
P
K
R
A
S
I
D
G
F
D
Q
Y
Site 25
Y342
S
I
D
G
F
D
Q
Y
F
M
T
R
S
L
E
Site 26
S347
D
Q
Y
F
M
T
R
S
L
E
N
N
R
R
N
Site 27
T370
E
N
F
N
C
K
L
T
S
S
G
T
Q
S
D
Site 28
S371
N
F
N
C
K
L
T
S
S
G
T
Q
S
D
D
Site 29
S372
F
N
C
K
L
T
S
S
G
T
Q
S
D
D
S
Site 30
T374
C
K
L
T
S
S
G
T
Q
S
D
D
S
T
R
Site 31
S376
L
T
S
S
G
T
Q
S
D
D
S
T
R
K
C
Site 32
S379
S
G
T
Q
S
D
D
S
T
R
K
C
T
G
E
Site 33
T380
G
T
Q
S
D
D
S
T
R
K
C
T
G
E
E
Site 34
T384
D
D
S
T
R
K
C
T
G
E
E
R
I
G
R
Site 35
S393
E
E
R
I
G
R
D
S
T
Y
E
Q
E
G
K
Site 36
T394
E
R
I
G
R
D
S
T
Y
E
Q
E
G
K
V
Site 37
Y395
R
I
G
R
D
S
T
Y
E
Q
E
G
K
V
Q
Site 38
Y444
D
G
R
M
L
L
Q
Y
I
R
A
V
R
F
N
Site 39
T456
R
F
N
G
S
A
G
T
P
V
M
F
N
E
N
Site 40
Y470
N
G
D
A
P
G
R
Y
D
I
F
Q
Y
Q
A
Site 41
Y475
G
R
Y
D
I
F
Q
Y
Q
A
T
N
G
S
A
Site 42
S481
Q
Y
Q
A
T
N
G
S
A
S
S
G
G
Y
Q
Site 43
Y487
G
S
A
S
S
G
G
Y
Q
A
V
G
Q
W
A
Site 44
S515
G
D
P
H
E
V
P
S
S
L
C
S
L
P
C
Site 45
S516
D
P
H
E
V
P
S
S
L
C
S
L
P
C
G
Site 46
S519
E
V
P
S
S
L
C
S
L
P
C
G
P
G
E
Site 47
Y546
H
C
E
A
C
D
G
Y
R
F
Q
V
D
E
F
Site 48
T574
N
H
T
G
C
R
P
T
P
V
V
R
L
S
W
Site 49
S580
P
T
P
V
V
R
L
S
W
S
S
P
W
A
A
Site 50
S582
P
V
V
R
L
S
W
S
S
P
W
A
A
P
P
Site 51
T613
T
F
V
R
Y
N
N
T
P
I
V
R
A
S
G
Site 52
S619
N
T
P
I
V
R
A
S
G
R
E
L
S
Y
V
Site 53
T670
L
S
Y
S
A
L
L
T
K
T
N
R
I
Y
R
Site 54
T672
Y
S
A
L
L
T
K
T
N
R
I
Y
R
I
F
Site 55
Y676
L
T
K
T
N
R
I
Y
R
I
F
E
Q
G
K
Site 56
S685
I
F
E
Q
G
K
R
S
V
T
P
P
P
F
I
Site 57
T687
E
Q
G
K
R
S
V
T
P
P
P
F
I
S
P
Site 58
S723
L
G
A
R
P
P
H
S
V
I
D
Y
E
E
Q
Site 59
Y727
P
P
H
S
V
I
D
Y
E
E
Q
R
T
V
D
Site 60
T732
I
D
Y
E
E
Q
R
T
V
D
P
E
Q
A
R
Site 61
T778
K
A
R
G
V
P
E
T
F
N
E
A
K
P
I
Site 62
S857
N
V
Q
K
R
K
R
S
L
K
A
T
S
T
V
Site 63
T861
R
K
R
S
L
K
A
T
S
T
V
A
A
P
P
Site 64
T863
R
S
L
K
A
T
S
T
V
A
A
P
P
K
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation