PhosphoNET

           
Protein Info 
   
Short Name:  SOX12
Full Name:  Transcription factor SOX-12
Alias:  Protein SOX-22
Type: 
Mass (Da):  34122
Number AA:  315
UniProt ID:  O15370
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T35REPGWCKTPSGHIKR
Site 2Y104RLKHMADYPDYKYRP
Site 3Y107HMADYPDYKYRPRKK
Site 4Y109ADYPDYKYRPRKKSK
Site 5S115KYRPRKKSKGAPAKA
Site 6S130RPRPPGGSGGGSRLK
Site 7S134PGGSGGGSRLKPGPQ
Site 8T181LEVRLVETPGRELWR
Site 9S207AERAQGPSGEGAAAA
Site 10S218AAAAAAASPTPSEDE
Site 11T220AAAAASPTPSEDEEP
Site 12S222AAASPTPSEDEEPEE
Site 13T244AEEGEEETVASGEES
Site 14S247GEEETVASGEESLGF
Site 15S256EESLGFLSRLPPGPA
Site 16S268GPAGLDCSALDRDPD
Site 17S280DPDLQPPSGTSHFEF
Site 18Y290SHFEFPDYCTPEVTE
Site 19T292FEFPDYCTPEVTEMI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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