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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SIGLEC5
Full Name:
Sialic acid-binding Ig-like lectin 5
Alias:
CD170; CD33 antigen-like 2; CD33L2; OB-binding protein 2; OB-BP2; obesity-binding protein 2; sialic acid binding Ig-like lectin 5; sialic acid-binding Ig-like lectin 5; SIGL5; SIGLEC-5
Type:
Adhesion
Mass (Da):
60715
Number AA:
551
UniProt ID:
O15389
International Prot ID:
IPI00021935
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005529
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T485
D
E
D
P
I
M
G
T
I
T
S
G
S
R
K
Site 2
T487
D
P
I
M
G
T
I
T
S
G
S
R
K
K
P
Site 3
S488
P
I
M
G
T
I
T
S
G
S
R
K
K
P
W
Site 4
S490
M
G
T
I
T
S
G
S
R
K
K
P
W
P
D
Site 5
S498
R
K
K
P
W
P
D
S
P
G
D
Q
A
S
P
Site 6
S504
D
S
P
G
D
Q
A
S
P
P
G
D
A
P
P
Site 7
Y520
E
E
Q
K
E
L
H
Y
A
S
L
S
F
S
E
Site 8
S522
Q
K
E
L
H
Y
A
S
L
S
F
S
E
M
K
Site 9
S524
E
L
H
Y
A
S
L
S
F
S
E
M
K
S
R
Site 10
S526
H
Y
A
S
L
S
F
S
E
M
K
S
R
E
P
Site 11
S530
L
S
F
S
E
M
K
S
R
E
P
K
D
Q
E
Site 12
S540
P
K
D
Q
E
A
P
S
T
T
E
Y
S
E
I
Site 13
T541
K
D
Q
E
A
P
S
T
T
E
Y
S
E
I
K
Site 14
Y544
E
A
P
S
T
T
E
Y
S
E
I
K
T
S
K
Site 15
S545
A
P
S
T
T
E
Y
S
E
I
K
T
S
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation