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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TOX3
Full Name:
TOX high mobility group box family member 3
Alias:
Cagf9; Tnrc9
Type:
Nucleus protein
Mass (Da):
63342
Number AA:
576
UniProt ID:
O15405
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y24
D
F
A
Q
C
L
G
Y
Y
G
Y
S
K
F
G
Site 2
Y25
F
A
Q
C
L
G
Y
Y
G
Y
S
K
F
G
N
Site 3
Y27
Q
C
L
G
Y
Y
G
Y
S
K
F
G
N
N
N
Site 4
Y36
K
F
G
N
N
N
N
Y
M
N
M
A
E
A
N
Site 5
T53
F
F
A
A
S
E
Q
T
F
H
T
P
S
L
G
Site 6
T56
A
S
E
Q
T
F
H
T
P
S
L
G
D
E
E
Site 7
S58
E
Q
T
F
H
T
P
S
L
G
D
E
E
F
E
Site 8
T70
E
F
E
I
P
P
I
T
P
P
P
E
S
D
P
Site 9
S75
P
I
T
P
P
P
E
S
D
P
A
L
G
M
P
Site 10
S97
A
L
S
D
P
L
P
S
Q
G
S
E
F
T
P
Site 11
T103
P
S
Q
G
S
E
F
T
P
Q
F
P
P
Q
S
Site 12
S110
T
P
Q
F
P
P
Q
S
L
D
L
P
S
I
T
Site 13
S115
P
Q
S
L
D
L
P
S
I
T
I
S
R
N
L
Site 14
S119
D
L
P
S
I
T
I
S
R
N
L
V
E
Q
D
Site 15
S139
S
G
L
H
M
D
Q
S
H
T
Q
V
S
Q
Y
Site 16
S144
D
Q
S
H
T
Q
V
S
Q
Y
R
Q
D
P
S
Site 17
S151
S
Q
Y
R
Q
D
P
S
L
I
M
R
S
I
V
Site 18
T175
V
M
P
P
A
Q
L
T
T
I
N
Q
S
Q
L
Site 19
T198
G
G
A
S
M
P
H
T
S
P
S
P
P
A
S
Site 20
S199
G
A
S
M
P
H
T
S
P
S
P
P
A
S
K
Site 21
S201
S
M
P
H
T
S
P
S
P
P
A
S
K
S
A
Site 22
S205
T
S
P
S
P
P
A
S
K
S
A
T
P
S
P
Site 23
S207
P
S
P
P
A
S
K
S
A
T
P
S
P
S
S
Site 24
T209
P
P
A
S
K
S
A
T
P
S
P
S
S
S
I
Site 25
S211
A
S
K
S
A
T
P
S
P
S
S
S
I
N
E
Site 26
S213
K
S
A
T
P
S
P
S
S
S
I
N
E
E
D
Site 27
S214
S
A
T
P
S
P
S
S
S
I
N
E
E
D
A
Site 28
S215
A
T
P
S
P
S
S
S
I
N
E
E
D
A
D
Site 29
S237
E
K
R
A
A
P
D
S
G
K
K
P
K
T
P
Site 30
T243
D
S
G
K
K
P
K
T
P
K
K
K
K
K
K
Site 31
S260
N
E
P
Q
K
P
V
S
A
Y
A
L
F
F
R
Site 32
T269
Y
A
L
F
F
R
D
T
Q
A
A
I
K
G
Q
Site 33
T281
K
G
Q
N
P
N
A
T
F
G
E
V
S
K
I
Site 34
S291
E
V
S
K
I
V
A
S
M
W
D
S
L
G
E
Site 35
S295
I
V
A
S
M
W
D
S
L
G
E
E
Q
K
Q
Site 36
Y304
G
E
E
Q
K
Q
V
Y
K
R
K
T
E
A
A
Site 37
T308
K
Q
V
Y
K
R
K
T
E
A
A
K
K
E
Y
Site 38
Y315
T
E
A
A
K
K
E
Y
L
K
A
L
A
A
Y
Site 39
S342
A
E
A
Q
T
I
R
S
V
Q
Q
T
L
A
S
Site 40
T346
T
I
R
S
V
Q
Q
T
L
A
S
T
N
L
T
Site 41
S349
S
V
Q
Q
T
L
A
S
T
N
L
T
S
S
L
Site 42
T360
T
S
S
L
L
L
N
T
P
L
S
Q
H
G
T
Site 43
T367
T
P
L
S
Q
H
G
T
V
S
A
S
P
Q
T
Site 44
S369
L
S
Q
H
G
T
V
S
A
S
P
Q
T
L
Q
Site 45
S371
Q
H
G
T
V
S
A
S
P
Q
T
L
Q
Q
S
Site 46
T374
T
V
S
A
S
P
Q
T
L
Q
Q
S
L
P
R
Site 47
S378
S
P
Q
T
L
Q
Q
S
L
P
R
S
I
A
P
Site 48
S382
L
Q
Q
S
L
P
R
S
I
A
P
K
P
L
T
Site 49
T389
S
I
A
P
K
P
L
T
M
R
L
P
M
N
Q
Site 50
T430
M
V
G
S
A
P
S
T
Q
V
S
P
S
V
Q
Site 51
S433
S
A
P
S
T
Q
V
S
P
S
V
Q
T
Q
Q
Site 52
S435
P
S
T
Q
V
S
P
S
V
Q
T
Q
Q
H
Q
Site 53
S526
L
Q
H
M
Q
H
Q
S
Q
P
S
P
R
Q
H
Site 54
S529
M
Q
H
Q
S
Q
P
S
P
R
Q
H
S
P
V
Site 55
S534
Q
P
S
P
R
Q
H
S
P
V
A
S
Q
I
T
Site 56
S538
R
Q
H
S
P
V
A
S
Q
I
T
S
P
I
P
Site 57
S549
S
P
I
P
A
I
G
S
P
Q
P
A
S
Q
Q
Site 58
S554
I
G
S
P
Q
P
A
S
Q
Q
H
Q
S
Q
I
Site 59
S559
P
A
S
Q
Q
H
Q
S
Q
I
Q
S
Q
T
Q
Site 60
S563
Q
H
Q
S
Q
I
Q
S
Q
T
Q
T
Q
V
L
Site 61
T567
Q
I
Q
S
Q
T
Q
T
Q
V
L
S
Q
V
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation