PhosphoNET

           
Protein Info 
   
Short Name:  INSIG1
Full Name:  Insulin-induced gene 1 protein
Alias: 
Type: 
Mass (Da):  29987
Number AA:  277
UniProt ID:  O15503
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S16WSCSCAHSARRRGPP
Site 2S26RRGPPRASAAGLAAK
Site 3S64DPAPRGRSAAMSGPE
Site 4S68RGRSAAMSGPEPGSP
Site 5S74MSGPEPGSPYPNTWH
Site 6Y76GPEPGSPYPNTWHHR
Site 7S149LLYPCIDSHLGEPHK
Site 8T203LSLGLWWTFDRSRSG
Site 9S207LWWTFDRSRSGLGLG
Site 10S209WTFDRSRSGLGLGIT
Site 11Y234FLVYNGVYQYTSPDF
Site 12Y236VYNGVYQYTSPDFLY
Site 13S238NGVYQYTSPDFLYIR
Site 14Y243YTSPDFLYIRSWLPC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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