KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
OGG1
Full Name:
N-glycosylase/DNA lyase
Alias:
8-hydroxyguanine DNA glycosylase; 8-oxoguanine DNA glycosylase; AP lyase; DNA-apurinic or apyrimidinic site lyase; HMMH; HOGG1; MUTM; OGG1 type 1d; OGG1 type 1e; OGG1 type 1g; OGG1 type 1h; OGH1
Type:
DNA repair; Lyase; Deoxyribonuclease
Mass (Da):
38780
Number AA:
UniProt ID:
O15527
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003684
GO:0004519
GO:0008534
PhosphoSite+
KinaseNET
Biological Process:
GO:0045007
GO:0006289
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
P
R
R
M
G
H
R
T
L
A
S
T
P
A
L
Site 2
S18
M
G
H
R
T
L
A
S
T
P
A
L
W
A
S
Site 3
S25
S
T
P
A
L
W
A
S
I
P
C
P
R
S
E
Site 4
S41
R
L
D
L
V
L
P
S
G
Q
S
F
R
W
R
Site 5
S44
L
V
L
P
S
G
Q
S
F
R
W
R
E
Q
S
Site 6
S51
S
F
R
W
R
E
Q
S
P
A
H
W
S
G
V
Site 7
T76
T
E
E
Q
L
H
C
T
V
Y
R
G
D
K
S
Site 8
Y78
E
Q
L
H
C
T
V
Y
R
G
D
K
S
Q
A
Site 9
S83
T
V
Y
R
G
D
K
S
Q
A
S
R
P
T
P
Site 10
T89
K
S
Q
A
S
R
P
T
P
D
E
L
E
A
V
Site 11
Y99
E
L
E
A
V
R
K
Y
F
Q
L
D
V
T
L
Site 12
T105
K
Y
F
Q
L
D
V
T
L
A
Q
L
Y
H
H
Site 13
Y110
D
V
T
L
A
Q
L
Y
H
H
W
G
S
V
D
Site 14
T156
N
N
N
I
A
R
I
T
G
M
V
E
R
L
C
Site 15
Y178
I
Q
L
D
D
V
T
Y
H
G
F
P
S
L
Q
Site 16
S183
V
T
Y
H
G
F
P
S
L
Q
A
L
A
G
P
Site 17
Y207
G
L
G
Y
R
A
R
Y
V
S
A
S
A
R
A
Site 18
S209
G
Y
R
A
R
Y
V
S
A
S
A
R
A
I
L
Site 19
S211
R
A
R
Y
V
S
A
S
A
R
A
I
L
E
E
Site 20
S231
W
L
Q
Q
L
R
E
S
S
Y
E
E
A
H
K
Site 21
S232
L
Q
Q
L
R
E
S
S
Y
E
E
A
H
K
A
Site 22
S280
H
I
A
Q
R
D
Y
S
W
H
P
T
T
S
Q
Site 23
T284
R
D
Y
S
W
H
P
T
T
S
Q
A
K
G
P
Site 24
S286
Y
S
W
H
P
T
T
S
Q
A
K
G
P
S
P
Site 25
S292
T
S
Q
A
K
G
P
S
P
Q
T
N
K
E
L
Site 26
S305
E
L
G
N
F
F
R
S
L
W
G
P
Y
A
G
Site 27
S326
F
S
A
D
L
R
Q
S
R
H
A
Q
E
P
P
Site 28
S340
P
A
K
R
R
K
G
S
K
G
P
E
G
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation