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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HERV-K_1q23.3 provirus ancestral Env polyprotein
Full Name:
HERV-K_1q23.3 provirus ancestral Env polyprotein
Alias:
Envelope polyprotein;HERV-K(C1a) envelope protein;HERV-K110 envelope protein;HERV-K18 envelope protein;HERV-K18 superantigen;IDDMK1,2 22 envelope protein;IDDMK1,2 22 superantigen
Type:
Mass (Da):
63671
Number AA:
560
UniProt ID:
O42043
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
M
D
N
P
I
E
V
Y
V
N
D
S
V
W
V
Site 2
T26
S
V
W
V
P
G
P
T
D
D
R
C
P
A
K
Site 3
Y49
N
I
S
I
G
Y
H
Y
P
P
I
C
L
G
R
Site 4
T74
N
W
L
V
E
V
P
T
V
S
P
N
S
R
F
Site 5
S76
L
V
E
V
P
T
V
S
P
N
S
R
F
T
Y
Site 6
S79
V
P
T
V
S
P
N
S
R
F
T
Y
H
M
V
Site 7
Y83
S
P
N
S
R
F
T
Y
H
M
V
S
G
M
S
Site 8
S87
R
F
T
Y
H
M
V
S
G
M
S
L
R
P
R
Site 9
Y103
N
C
L
Q
D
F
S
Y
Q
R
S
L
K
F
R
Site 10
S106
Q
D
F
S
Y
Q
R
S
L
K
F
R
P
K
G
Site 11
T115
K
F
R
P
K
G
K
T
C
P
K
E
I
P
K
Site 12
S170
N
C
S
G
Q
T
Q
S
C
P
S
A
Q
V
S
Site 13
S173
G
Q
T
Q
S
C
P
S
A
Q
V
S
P
A
V
Site 14
S177
S
C
P
S
A
Q
V
S
P
A
V
D
S
D
L
Site 15
S182
Q
V
S
P
A
V
D
S
D
L
T
E
S
L
D
Site 16
T185
P
A
V
D
S
D
L
T
E
S
L
D
K
H
K
Site 17
S187
V
D
S
D
L
T
E
S
L
D
K
H
K
H
K
Site 18
Y200
H
K
K
L
Q
S
F
Y
L
W
E
W
E
E
K
Site 19
S210
E
W
E
E
K
G
I
S
T
P
R
P
K
I
I
Site 20
T211
W
E
E
K
G
I
S
T
P
R
P
K
I
I
S
Site 21
S218
T
P
R
P
K
I
I
S
P
V
S
G
P
E
H
Site 22
S221
P
K
I
I
S
P
V
S
G
P
E
H
P
E
L
Site 23
T232
H
P
E
L
W
R
L
T
V
A
S
H
H
I
R
Site 24
T246
R
I
W
S
G
N
Q
T
L
E
T
R
Y
R
K
Site 25
T249
S
G
N
Q
T
L
E
T
R
Y
R
K
P
F
Y
Site 26
Y251
N
Q
T
L
E
T
R
Y
R
K
P
F
Y
T
I
Site 27
Y256
T
R
Y
R
K
P
F
Y
T
I
D
L
N
S
I
Site 28
T257
R
Y
R
K
P
F
Y
T
I
D
L
N
S
I
L
Site 29
S289
N
I
V
I
K
P
A
S
Q
T
I
T
C
E
N
Site 30
T293
K
P
A
S
Q
T
I
T
C
E
N
C
R
L
F
Site 31
T328
G
M
W
I
P
V
S
T
D
R
P
W
E
A
S
Site 32
S335
T
D
R
P
W
E
A
S
P
S
I
H
I
L
T
Site 33
S337
R
P
W
E
A
S
P
S
I
H
I
L
T
E
I
Site 34
Y392
Q
S
V
N
F
V
N
Y
W
Q
K
N
S
T
R
Site 35
S403
N
S
T
R
L
W
N
S
Q
S
S
I
D
Q
K
Site 36
S405
T
R
L
W
N
S
Q
S
S
I
D
Q
K
L
A
Site 37
S406
R
L
W
N
S
Q
S
S
I
D
Q
K
L
A
S
Site 38
S413
S
I
D
Q
K
L
A
S
Q
I
N
D
L
R
Q
Site 39
T450
N
T
S
D
F
C
I
T
P
Q
I
Y
N
E
S
Site 40
T476
Q
G
R
E
D
N
L
T
L
D
I
S
K
L
K
Site 41
S480
D
N
L
T
L
D
I
S
K
L
K
E
Q
I
F
Site 42
T547
L
L
L
V
C
R
C
T
Q
Q
L
R
R
D
S
Site 43
S554
T
Q
Q
L
R
R
D
S
D
I
E
N
G
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation