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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLXNB1
Full Name:
Plexin-B1
Alias:
KIAA0407; Plexin 5; Plexin B1; PLEXIN-B1; PLXB1; PLXN5; Semaphorin receptor; Semaphorin receptor SEP; SEP
Type:
Receptor, misc.
Mass (Da):
232298
Number AA:
2135
UniProt ID:
O43157
International Prot ID:
IPI00006644
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005887
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0017154
GO:0030215
PhosphoSite+
KinaseNET
Biological Process:
GO:0016477
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S1220
E
Q
L
R
C
E
T
S
P
R
P
T
P
A
T
Site 2
Y1374
L
N
P
T
P
F
S
Y
E
A
D
P
T
L
Q
Site 3
S1481
H
V
Q
Y
D
G
E
S
P
G
A
F
P
V
A
Site 4
S1515
V
L
M
Y
R
R
K
S
K
Q
A
L
R
D
Y
Site 5
Y1522
S
K
Q
A
L
R
D
Y
K
K
V
Q
I
Q
L
Site 6
S1534
I
Q
L
E
N
L
E
S
S
V
R
D
R
C
K
Site 7
S1535
Q
L
E
N
L
E
S
S
V
R
D
R
C
K
K
Site 8
T1549
K
E
F
T
D
L
M
T
E
M
T
D
L
T
S
Site 9
T1555
M
T
E
M
T
D
L
T
S
D
L
L
G
S
G
Site 10
Y1568
S
G
I
P
F
L
D
Y
K
V
Y
A
E
R
I
Site 11
S1583
F
F
P
G
H
R
E
S
P
L
H
R
D
L
G
Site 12
S1594
R
D
L
G
V
P
E
S
R
R
P
T
V
E
Q
Site 13
T1598
V
P
E
S
R
R
P
T
V
E
Q
G
L
G
Q
Site 14
S1607
E
Q
G
L
G
Q
L
S
N
L
L
N
S
K
L
Site 15
S1625
K
F
I
H
T
L
E
S
Q
R
T
F
S
A
R
Site 16
T1628
H
T
L
E
S
Q
R
T
F
S
A
R
D
R
A
Site 17
S1630
L
E
S
Q
R
T
F
S
A
R
D
R
A
Y
V
Site 18
Y1651
A
L
H
G
K
L
E
Y
F
T
D
I
L
R
T
Site 19
Y1667
L
S
D
L
V
A
Q
Y
V
A
K
N
P
K
L
Site 20
T1679
P
K
L
M
L
R
R
T
E
T
V
V
E
K
L
Site 21
T1681
L
M
L
R
R
T
E
T
V
V
E
K
L
L
T
Site 22
Y1708
D
S
V
G
E
P
L
Y
M
L
F
R
G
I
K
Site 23
S1725
V
D
K
G
P
V
D
S
V
T
G
K
A
K
Y
Site 24
T1727
K
G
P
V
D
S
V
T
G
K
A
K
Y
T
L
Site 25
Y1732
S
V
T
G
K
A
K
Y
T
L
N
D
N
R
L
Site 26
Y1746
L
L
R
E
D
V
E
Y
R
P
L
T
L
N
A
Site 27
T1776
V
K
V
L
D
C
D
T
I
S
Q
A
K
E
K
Site 28
S1778
V
L
D
C
D
T
I
S
Q
A
K
E
K
M
L
Site 29
Y1789
E
K
M
L
D
Q
L
Y
K
G
V
P
L
T
Q
Site 30
T1795
L
Y
K
G
V
P
L
T
Q
R
P
D
P
R
T
Site 31
T1802
T
Q
R
P
D
P
R
T
L
D
V
E
W
R
S
Site 32
T1823
I
L
S
D
E
D
V
T
S
E
V
Q
G
L
W
Site 33
S1824
L
S
D
E
D
V
T
S
E
V
Q
G
L
W
R
Site 34
T1835
G
L
W
R
R
L
N
T
L
Q
H
Y
K
V
P
Site 35
Y1839
R
L
N
T
L
Q
H
Y
K
V
P
D
G
A
T
Site 36
Y1864
V
L
R
E
N
Q
D
Y
V
P
G
E
R
T
P
Site 37
T1870
D
Y
V
P
G
E
R
T
P
M
L
E
D
V
D
Site 38
S1890
P
W
H
L
V
K
P
S
D
E
P
E
P
P
R
Site 39
S1902
P
P
R
P
R
R
G
S
L
R
G
G
E
R
E
Site 40
T1928
R
L
L
S
M
K
G
T
L
Q
K
F
V
D
D
Site 41
T1978
D
T
I
H
I
W
K
T
N
S
L
P
L
R
F
Site 42
T2021
Q
T
F
M
D
A
C
T
L
A
D
H
K
L
G
Site 43
S2031
D
H
K
L
G
R
D
S
P
I
N
K
L
L
Y
Site 44
Y2038
S
P
I
N
K
L
L
Y
A
R
D
I
P
R
Y
Site 45
Y2045
Y
A
R
D
I
P
R
Y
K
R
M
V
E
R
Y
Site 46
Y2052
Y
K
R
M
V
E
R
Y
Y
A
D
I
R
Q
T
Site 47
Y2053
K
R
M
V
E
R
Y
Y
A
D
I
R
Q
T
V
Site 48
T2059
Y
Y
A
D
I
R
Q
T
V
P
A
S
D
Q
E
Site 49
S2063
I
R
Q
T
V
P
A
S
D
Q
E
M
N
S
V
Site 50
S2069
A
S
D
Q
E
M
N
S
V
L
A
E
L
S
W
Site 51
S2075
N
S
V
L
A
E
L
S
W
N
Y
S
G
D
L
Site 52
S2079
A
E
L
S
W
N
Y
S
G
D
L
G
A
R
V
Site 53
Y2092
R
V
A
L
H
E
L
Y
K
Y
I
N
K
Y
Y
Site 54
Y2094
A
L
H
E
L
Y
K
Y
I
N
K
Y
Y
D
Q
Site 55
Y2098
L
Y
K
Y
I
N
K
Y
Y
D
Q
I
I
T
A
Site 56
Y2099
Y
K
Y
I
N
K
Y
Y
D
Q
I
I
T
A
L
Site 57
T2111
T
A
L
E
E
D
G
T
A
Q
K
M
Q
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation