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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0409
Full Name:
Ribosomal RNA-processing protein 8
Alias:
HUCE1
Type:
Uncharacterized protein
Mass (Da):
50715
Number AA:
456
UniProt ID:
O43159
International Prot ID:
IPI00304932
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0008168
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006364
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
S
R
P
P
P
A
A
S
S
Q
N
K
G
S
K
Site 2
S30
R
P
P
P
A
A
S
S
Q
N
K
G
S
K
R
Site 3
S35
A
S
S
Q
N
K
G
S
K
R
R
Q
L
L
A
Site 4
T43
K
R
R
Q
L
L
A
T
L
R
A
L
E
A
A
Site 5
S51
L
R
A
L
E
A
A
S
L
S
Q
H
P
P
S
Site 6
S53
A
L
E
A
A
S
L
S
Q
H
P
P
S
L
C
Site 7
S58
S
L
S
Q
H
P
P
S
L
C
I
S
D
S
E
Site 8
S62
H
P
P
S
L
C
I
S
D
S
E
E
E
E
E
Site 9
S64
P
S
L
C
I
S
D
S
E
E
E
E
E
E
R
Site 10
S80
K
K
C
P
K
K
A
S
F
A
S
A
S
A
E
Site 11
S83
P
K
K
A
S
F
A
S
A
S
A
E
V
G
K
Site 12
S85
K
A
S
F
A
S
A
S
A
E
V
G
K
K
G
Site 13
S104
Q
K
Q
G
P
P
C
S
D
S
E
E
E
V
E
Site 14
S106
Q
G
P
P
C
S
D
S
E
E
E
V
E
R
K
Site 15
S124
H
K
Q
A
L
V
G
S
D
S
A
E
D
E
K
Site 16
S126
Q
A
L
V
G
S
D
S
A
E
D
E
K
R
K
Site 17
T154
H
L
D
N
V
D
Q
T
G
P
K
A
W
K
G
Site 18
S171
T
N
D
P
P
K
Q
S
P
G
S
T
S
P
K
Site 19
S174
P
P
K
Q
S
P
G
S
T
S
P
K
P
P
H
Site 20
T175
P
K
Q
S
P
G
S
T
S
P
K
P
P
H
T
Site 21
S176
K
Q
S
P
G
S
T
S
P
K
P
P
H
T
L
Site 22
T182
T
S
P
K
P
P
H
T
L
S
R
K
Q
W
R
Site 23
S184
P
K
P
P
H
T
L
S
R
K
Q
W
R
N
R
Site 24
S223
P
T
E
K
T
E
V
S
P
V
P
R
T
D
S
Site 25
T228
E
V
S
P
V
P
R
T
D
S
H
E
A
R
A
Site 26
S230
S
P
V
P
R
T
D
S
H
E
A
R
A
G
A
Site 27
Y253
L
D
G
A
R
F
R
Y
L
N
E
Q
L
Y
S
Site 28
Y259
R
Y
L
N
E
Q
L
Y
S
G
P
S
S
A
A
Site 29
S260
Y
L
N
E
Q
L
Y
S
G
P
S
S
A
A
Q
Site 30
S264
Q
L
Y
S
G
P
S
S
A
A
Q
R
L
F
Q
Site 31
Y280
D
P
E
A
F
L
L
Y
H
R
G
F
Q
S
Q
Site 32
S286
L
Y
H
R
G
F
Q
S
Q
V
K
K
W
P
L
Site 33
S309
D
L
R
Q
R
P
A
S
L
V
V
A
D
F
G
Site 34
S324
C
G
D
C
R
L
A
S
S
I
R
N
P
V
H
Site 35
S325
G
D
C
R
L
A
S
S
I
R
N
P
V
H
C
Site 36
T369
F
C
L
S
L
M
G
T
N
I
R
D
F
L
E
Site 37
T402
S
R
F
E
D
V
R
T
F
L
R
A
V
T
K
Site 38
S416
K
L
G
F
K
I
V
S
K
D
L
T
N
S
H
Site 39
S444
V
G
P
K
A
Q
L
S
G
L
Q
L
Q
P
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation