KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZBTB24
Full Name:
Zinc finger and BTB domain-containing protein 24
Alias:
BIF1; KIAA0441; PATZ2; POZ (BTB) and AT hook containing zinc finger 2; ZBT24; zinc finger 450; zinc finger and BTB domain containing 24; ZNF450
Type:
Mass (Da):
78280
Number AA:
UniProt ID:
O43167
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
E
T
S
P
E
P
S
G
Q
L
Site 2
S9
A
E
T
S
P
E
P
S
G
Q
L
V
V
H
S
Site 3
S16
S
G
Q
L
V
V
H
S
D
A
H
S
D
T
V
Site 4
T22
H
S
D
A
H
S
D
T
V
L
A
S
F
E
D
Site 5
S26
H
S
D
T
V
L
A
S
F
E
D
Q
R
K
K
Site 6
S63
A
A
S
S
E
Y
F
S
M
M
F
A
E
E
G
Site 7
S75
E
E
G
E
I
G
Q
S
I
Y
M
L
E
G
M
Site 8
Y98
L
E
F
I
Y
T
G
Y
L
H
A
S
E
K
S
Site 9
S102
Y
T
G
Y
L
H
A
S
E
K
S
T
E
Q
I
Site 10
S134
D
F
Q
N
N
H
S
S
P
K
P
T
T
L
N
Site 11
T139
H
S
S
P
K
P
T
T
L
N
T
A
G
A
P
Site 12
S176
N
T
L
Q
E
E
K
S
E
L
A
A
E
E
E
Site 13
S219
A
A
K
E
K
E
E
S
E
P
T
C
E
P
S
Site 14
T222
E
K
E
E
S
E
P
T
C
E
P
S
R
E
E
Site 15
S226
S
E
P
T
C
E
P
S
R
E
E
E
M
P
V
Site 16
Y239
P
V
E
K
D
E
N
Y
D
P
K
T
E
D
G
Site 17
T243
D
E
N
Y
D
P
K
T
E
D
G
Q
A
S
Q
Site 18
S249
K
T
E
D
G
Q
A
S
Q
S
R
Y
S
K
R
Site 19
S251
E
D
G
Q
A
S
Q
S
R
Y
S
K
R
R
I
Site 20
Y253
G
Q
A
S
Q
S
R
Y
S
K
R
R
I
W
R
Site 21
S254
Q
A
S
Q
S
R
Y
S
K
R
R
I
W
R
S
Site 22
S261
S
K
R
R
I
W
R
S
V
K
L
K
D
Y
K
Site 23
Y267
R
S
V
K
L
K
D
Y
K
L
V
G
D
Q
E
Site 24
S278
G
D
Q
E
D
H
G
S
A
K
R
I
C
G
R
Site 25
S315
F
L
A
I
H
Q
R
S
H
T
G
E
R
P
F
Site 26
T317
A
I
H
Q
R
S
H
T
G
E
R
P
F
K
C
Site 27
S336
K
G
F
A
Q
K
H
S
L
Q
V
H
T
R
M
Site 28
T345
Q
V
H
T
R
M
H
T
G
E
R
P
Y
T
C
Site 29
Y350
M
H
T
G
E
R
P
Y
T
C
T
V
C
S
K
Site 30
T351
H
T
G
E
R
P
Y
T
C
T
V
C
S
K
A
Site 31
T353
G
E
R
P
Y
T
C
T
V
C
S
K
A
L
T
Site 32
T360
T
V
C
S
K
A
L
T
T
K
H
S
L
L
E
Site 33
S364
K
A
L
T
T
K
H
S
L
L
E
H
M
S
L
Site 34
S370
H
S
L
L
E
H
M
S
L
H
S
G
Q
K
S
Site 35
S373
L
E
H
M
S
L
H
S
G
Q
K
S
F
T
C
Site 36
S377
S
L
H
S
G
Q
K
S
F
T
C
D
Q
C
G
Site 37
Y386
T
C
D
Q
C
G
K
Y
F
S
Q
N
R
Q
L
Site 38
S388
D
Q
C
G
K
Y
F
S
Q
N
R
Q
L
K
S
Site 39
S395
S
Q
N
R
Q
L
K
S
H
Y
R
V
H
T
G
Site 40
Y397
N
R
Q
L
K
S
H
Y
R
V
H
T
G
H
S
Site 41
T401
K
S
H
Y
R
V
H
T
G
H
S
L
P
E
C
Site 42
S419
H
R
K
F
M
D
V
S
Q
L
K
K
H
L
R
Site 43
T427
Q
L
K
K
H
L
R
T
H
T
G
E
K
P
F
Site 44
T429
K
K
H
L
R
T
H
T
G
E
K
P
F
T
C
Site 45
T435
H
T
G
E
K
P
F
T
C
E
I
C
G
K
S
Site 46
S442
T
C
E
I
C
G
K
S
F
T
A
K
S
S
L
Site 47
T444
E
I
C
G
K
S
F
T
A
K
S
S
L
Q
T
Site 48
S447
G
K
S
F
T
A
K
S
S
L
Q
T
H
I
R
Site 49
T451
T
A
K
S
S
L
Q
T
H
I
R
I
H
R
G
Site 50
Y462
I
H
R
G
E
K
P
Y
S
C
G
I
C
G
K
Site 51
S463
H
R
G
E
K
P
Y
S
C
G
I
C
G
K
S
Site 52
S470
S
C
G
I
C
G
K
S
F
S
D
S
S
A
K
Site 53
S472
G
I
C
G
K
S
F
S
D
S
S
A
K
R
R
Site 54
S474
C
G
K
S
F
S
D
S
S
A
K
R
R
H
C
Site 55
S475
G
K
S
F
S
D
S
S
A
K
R
R
H
C
I
Site 56
S491
H
T
G
K
K
P
F
S
C
P
E
C
N
L
Q
Site 57
S519
H
S
K
E
K
H
A
S
D
A
S
S
I
S
G
Site 58
S522
E
K
H
A
S
D
A
S
S
I
S
G
S
S
N
Site 59
S523
K
H
A
S
D
A
S
S
I
S
G
S
S
N
T
Site 60
S525
A
S
D
A
S
S
I
S
G
S
S
N
T
E
E
Site 61
S527
D
A
S
S
I
S
G
S
S
N
T
E
E
V
R
Site 62
Y542
N
I
L
Q
L
Q
P
Y
Q
L
S
T
S
G
E
Site 63
S545
Q
L
Q
P
Y
Q
L
S
T
S
G
E
Q
E
I
Site 64
S574
P
G
P
S
Q
G
I
S
I
V
T
A
E
S
S
Site 65
T577
S
Q
G
I
S
I
V
T
A
E
S
S
Q
N
M
Site 66
S581
S
I
V
T
A
E
S
S
Q
N
M
T
A
D
Q
Site 67
T596
A
A
N
L
T
L
L
T
Q
Q
P
E
Q
L
Q
Site 68
S619
E
Q
T
E
H
I
Q
S
L
N
M
I
E
S
Q
Site 69
S625
Q
S
L
N
M
I
E
S
Q
M
G
P
S
Q
T
Site 70
S630
I
E
S
Q
M
G
P
S
Q
T
E
P
V
H
V
Site 71
S663
E
E
L
H
L
A
T
S
T
S
D
P
A
Q
H
Site 72
S665
L
H
L
A
T
S
T
S
D
P
A
Q
H
L
Q
Site 73
T674
P
A
Q
H
L
Q
L
T
Q
E
P
G
P
P
P
Site 74
T683
E
P
G
P
P
P
P
T
H
H
V
P
Q
P
T
Site 75
T690
T
H
H
V
P
Q
P
T
P
L
G
Q
E
Q
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation