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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PHF1
Full Name:
PHD finger protein 1
Alias:
Polycomb-like protein 1
Type:
Mass (Da):
62078
Number AA:
567
UniProt ID:
O43189
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
Q
P
P
R
L
S
R
S
G
A
S
S
L
Site 2
S10
Q
P
P
R
L
S
R
S
G
A
S
S
L
W
D
Site 3
S14
L
S
R
S
G
A
S
S
L
W
D
P
A
S
P
Site 4
S20
S
S
L
W
D
P
A
S
P
A
P
T
S
G
P
Site 5
T24
D
P
A
S
P
A
P
T
S
G
P
R
P
R
L
Site 6
S25
P
A
S
P
A
P
T
S
G
P
R
P
R
L
W
Site 7
Y47
R
W
T
D
G
L
L
Y
L
G
T
I
K
K
V
Site 8
S106
V
P
G
N
R
L
V
S
C
E
K
C
R
H
A
Site 9
T132
A
P
G
E
G
E
G
T
S
W
V
C
R
Q
C
Site 10
T145
Q
C
V
F
A
I
A
T
K
R
G
G
A
L
K
Site 11
Y156
G
A
L
K
K
G
P
Y
A
R
A
M
L
G
M
Site 12
Y169
G
M
K
L
S
L
P
Y
G
L
K
G
L
D
W
Site 13
Y188
L
S
N
R
Q
Q
S
Y
C
Y
C
G
G
P
G
Site 14
Y225
C
L
S
K
P
L
L
Y
G
D
R
F
Y
E
F
Site 15
Y260
D
V
A
H
L
V
L
Y
H
L
S
V
C
C
K
Site 16
Y270
S
V
C
C
K
K
K
Y
F
D
F
D
R
E
I
Site 17
S287
F
T
S
E
N
W
D
S
L
L
L
G
E
L
S
Site 18
S294
S
L
L
L
G
E
L
S
D
T
P
K
G
E
R
Site 19
T296
L
L
G
E
L
S
D
T
P
K
G
E
R
S
S
Site 20
S302
D
T
P
K
G
E
R
S
S
K
L
L
S
A
L
Site 21
S303
T
P
K
G
E
R
S
S
K
L
L
S
A
L
N
Site 22
S307
E
R
S
S
K
L
L
S
A
L
N
S
H
K
D
Site 23
S311
K
L
L
S
A
L
N
S
H
K
D
R
F
I
S
Site 24
S318
S
H
K
D
R
F
I
S
G
R
E
I
K
K
R
Site 25
T343
P
P
P
V
E
P
P
T
G
D
G
A
L
T
S
Site 26
T349
P
T
G
D
G
A
L
T
S
F
P
S
G
Q
G
Site 27
S350
T
G
D
G
A
L
T
S
F
P
S
G
Q
G
P
Site 28
S353
G
A
L
T
S
F
P
S
G
Q
G
P
G
G
G
Site 29
S362
Q
G
P
G
G
G
V
S
R
P
L
G
K
R
R
Site 30
S391
V
E
E
L
G
P
P
S
A
V
R
N
Q
P
E
Site 31
S415
L
Q
R
A
L
Q
A
S
V
S
P
P
S
P
S
Site 32
S417
R
A
L
Q
A
S
V
S
P
P
S
P
S
P
N
Site 33
S420
Q
A
S
V
S
P
P
S
P
S
P
N
Q
S
Y
Site 34
S422
S
V
S
P
P
S
P
S
P
N
Q
S
Y
Q
G
Site 35
S426
P
S
P
S
P
N
Q
S
Y
Q
G
S
S
G
Y
Site 36
Y427
S
P
S
P
N
Q
S
Y
Q
G
S
S
G
Y
N
Site 37
S430
P
N
Q
S
Y
Q
G
S
S
G
Y
N
F
R
P
Site 38
T438
S
G
Y
N
F
R
P
T
D
A
R
C
L
P
S
Site 39
S446
D
A
R
C
L
P
S
S
P
I
R
M
F
A
S
Site 40
S453
S
P
I
R
M
F
A
S
F
H
P
S
A
S
T
Site 41
S457
M
F
A
S
F
H
P
S
A
S
T
A
G
T
S
Site 42
S459
A
S
F
H
P
S
A
S
T
A
G
T
S
G
D
Site 43
T463
P
S
A
S
T
A
G
T
S
G
D
S
G
P
P
Site 44
S467
T
A
G
T
S
G
D
S
G
P
P
D
R
S
P
Site 45
S473
D
S
G
P
P
D
R
S
P
L
E
L
H
I
G
Site 46
T483
E
L
H
I
G
F
P
T
D
I
P
K
S
A
P
Site 47
S488
F
P
T
D
I
P
K
S
A
P
H
S
M
T
A
Site 48
S492
I
P
K
S
A
P
H
S
M
T
A
S
S
S
S
Site 49
T494
K
S
A
P
H
S
M
T
A
S
S
S
S
V
S
Site 50
S496
A
P
H
S
M
T
A
S
S
S
S
V
S
S
P
Site 51
S497
P
H
S
M
T
A
S
S
S
S
V
S
S
P
S
Site 52
S498
H
S
M
T
A
S
S
S
S
V
S
S
P
S
P
Site 53
S499
S
M
T
A
S
S
S
S
V
S
S
P
S
P
G
Site 54
S501
T
A
S
S
S
S
V
S
S
P
S
P
G
L
P
Site 55
S502
A
S
S
S
S
V
S
S
P
S
P
G
L
P
R
Site 56
S504
S
S
S
V
S
S
P
S
P
G
L
P
R
R
S
Site 57
S511
S
P
G
L
P
R
R
S
A
P
P
S
P
L
C
Site 58
S515
P
R
R
S
A
P
P
S
P
L
C
R
S
L
S
Site 59
S520
P
P
S
P
L
C
R
S
L
S
P
G
T
G
G
Site 60
S522
S
P
L
C
R
S
L
S
P
G
T
G
G
G
V
Site 61
Y535
G
V
R
G
G
V
G
Y
L
S
R
G
D
P
V
Site 62
S537
R
G
G
V
G
Y
L
S
R
G
D
P
V
R
V
Site 63
S554
R
R
V
R
P
D
G
S
V
Q
Y
L
V
E
W
Site 64
Y557
R
P
D
G
S
V
Q
Y
L
V
E
W
G
G
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation