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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DYNC1LI2
Full Name:
Cytoplasmic dynein 1 light intermediate chain 2
Alias:
DC1L2; DYJ2; Dynein light intermediate chain 2, cytosolic; Dynein, cytoplasmic 1, light intermediate chain 2; LIC2; LIC-2; LIC53/55
Type:
Mass (Da):
54099
Number AA:
492
UniProt ID:
O43237
International Prot ID:
IPI00011592
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005868
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003774
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T26
V
A
A
A
G
D
L
T
S
E
E
E
E
G
Q
Site 2
S27
A
A
A
G
D
L
T
S
E
E
E
E
G
Q
S
Site 3
S34
S
E
E
E
E
G
Q
S
L
W
S
S
I
L
S
Site 4
S37
E
E
G
Q
S
L
W
S
S
I
L
S
E
V
S
Site 5
S38
E
G
Q
S
L
W
S
S
I
L
S
E
V
S
T
Site 6
S41
S
L
W
S
S
I
L
S
E
V
S
T
R
A
R
Site 7
S44
S
S
I
L
S
E
V
S
T
R
A
R
S
K
L
Site 8
T45
S
I
L
S
E
V
S
T
R
A
R
S
K
L
P
Site 9
S49
E
V
S
T
R
A
R
S
K
L
P
S
G
K
N
Site 10
S53
R
A
R
S
K
L
P
S
G
K
N
I
L
V
F
Site 11
T69
E
D
G
S
G
K
T
T
L
M
T
K
L
Q
G
Site 12
Y88
K
K
G
R
G
L
E
Y
L
Y
L
S
V
H
D
Site 13
Y90
G
R
G
L
E
Y
L
Y
L
S
V
H
D
E
D
Site 14
S92
G
L
E
Y
L
Y
L
S
V
H
D
E
D
R
D
Site 15
T144
A
D
M
S
R
P
W
T
V
M
E
S
L
Q
K
Site 16
S154
E
S
L
Q
K
W
A
S
V
L
R
E
H
I
D
Site 17
Y184
F
V
K
D
F
Q
D
Y
M
E
P
E
E
G
C
Site 18
S194
P
E
E
G
C
Q
G
S
P
Q
R
R
G
P
L
Site 19
T202
P
Q
R
R
G
P
L
T
S
G
S
D
E
E
N
Site 20
S203
Q
R
R
G
P
L
T
S
G
S
D
E
E
N
V
Site 21
S205
R
G
P
L
T
S
G
S
D
E
E
N
V
A
L
Site 22
S238
C
T
K
C
D
A
V
S
V
L
E
K
E
H
D
Site 23
Y246
V
L
E
K
E
H
D
Y
R
D
E
H
L
D
F
Site 24
Y271
Q
Y
G
A
A
L
I
Y
T
S
V
K
E
E
K
Site 25
S273
G
A
A
L
I
Y
T
S
V
K
E
E
K
N
L
Site 26
Y284
E
K
N
L
D
L
L
Y
K
Y
I
V
H
K
T
Site 27
Y286
N
L
D
L
L
Y
K
Y
I
V
H
K
T
Y
G
Site 28
T329
I
L
H
E
N
F
T
T
V
K
P
E
D
A
Y
Site 29
Y336
T
V
K
P
E
D
A
Y
E
D
F
I
V
K
P
Site 30
T376
L
L
A
K
Q
P
A
T
P
T
R
A
S
E
S
Site 31
S381
P
A
T
P
T
R
A
S
E
S
P
A
R
G
P
Site 32
S383
T
P
T
R
A
S
E
S
P
A
R
G
P
S
G
Site 33
S389
E
S
P
A
R
G
P
S
G
S
P
R
T
Q
G
Site 34
S391
P
A
R
G
P
S
G
S
P
R
T
Q
G
R
G
Site 35
T394
G
P
S
G
S
P
R
T
Q
G
R
G
G
P
A
Site 36
S402
Q
G
R
G
G
P
A
S
V
P
S
S
S
P
G
Site 37
S405
G
G
P
A
S
V
P
S
S
S
P
G
T
S
V
Site 38
S406
G
P
A
S
V
P
S
S
S
P
G
T
S
V
K
Site 39
S407
P
A
S
V
P
S
S
S
P
G
T
S
V
K
K
Site 40
T410
V
P
S
S
S
P
G
T
S
V
K
K
P
D
P
Site 41
S411
P
S
S
S
P
G
T
S
V
K
K
P
D
P
N
Site 42
S425
N
I
K
N
N
A
A
S
E
G
V
L
A
S
F
Site 43
S438
S
F
F
N
S
L
L
S
K
K
T
G
S
P
G
Site 44
T441
N
S
L
L
S
K
K
T
G
S
P
G
S
P
G
Site 45
S443
L
L
S
K
K
T
G
S
P
G
S
P
G
A
G
Site 46
S446
K
K
T
G
S
P
G
S
P
G
A
G
G
V
Q
Site 47
S454
P
G
A
G
G
V
Q
S
T
A
K
K
S
G
Q
Site 48
T455
G
A
G
G
V
Q
S
T
A
K
K
S
G
Q
K
Site 49
S459
V
Q
S
T
A
K
K
S
G
Q
K
T
V
L
S
Site 50
T463
A
K
K
S
G
Q
K
T
V
L
S
N
V
Q
E
Site 51
S466
S
G
Q
K
T
V
L
S
N
V
Q
E
E
L
D
Site 52
T476
Q
E
E
L
D
R
M
T
R
K
P
D
S
M
V
Site 53
S481
R
M
T
R
K
P
D
S
M
V
T
N
S
S
T
Site 54
S486
P
D
S
M
V
T
N
S
S
T
E
N
E
A
_
Site 55
S487
D
S
M
V
T
N
S
S
T
E
N
E
A
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation