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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAPSS1
Full Name:
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1
Alias:
Atp sulfurylase/aps kinase; Atpsk1; Bifunctional atp sulfurylase/adenosine 5''-phosphosulfate kinase; EC 2.7.1.25; EC 2.7.7.4; Paps sunthetase; Paps synthase; Paps1; Papss; Sk1; Sulfurylase kinase 1
Type:
Uncharacterized protein
Mass (Da):
70833
Number AA:
624
UniProt ID:
O43252
International Prot ID:
IPI00011619
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004020
GO:0004781
PhosphoSite+
KinaseNET
Biological Process:
GO:0001501
GO:0000103
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
L
C
K
K
V
K
L
S
N
N
A
Q
N
W
G
Site 2
Y30
Q
R
A
T
N
V
T
Y
Q
A
H
H
V
S
R
Site 3
S36
T
Y
Q
A
H
H
V
S
R
N
K
R
G
Q
V
Site 4
S102
L
N
K
N
L
G
F
S
P
E
D
R
E
E
N
Site 5
S133
V
C
I
T
S
F
I
S
P
Y
T
Q
D
R
N
Site 6
T136
T
S
F
I
S
P
Y
T
Q
D
R
N
N
A
R
Site 7
T186
A
G
E
I
K
G
F
T
G
I
D
S
E
Y
E
Site 8
S190
K
G
F
T
G
I
D
S
E
Y
E
K
P
E
A
Site 9
Y192
F
T
G
I
D
S
E
Y
E
K
P
E
A
P
E
Site 10
T204
A
P
E
L
V
L
K
T
D
S
C
D
V
N
D
Site 11
S231
D
I
V
P
V
D
A
S
Y
E
V
K
E
L
Y
Site 12
Y238
S
Y
E
V
K
E
L
Y
V
P
E
N
K
L
H
Site 13
T249
N
K
L
H
L
A
K
T
D
A
E
T
L
P
A
Site 14
Y287
G
F
M
R
E
R
E
Y
L
Q
C
L
H
F
D
Site 15
T324
K
E
R
L
D
G
C
T
A
F
A
L
M
Y
E
Site 16
Y388
L
Q
V
L
D
R
V
Y
W
N
D
G
L
D
Q
Site 17
Y396
W
N
D
G
L
D
Q
Y
R
L
T
P
T
E
L
Site 18
T399
G
L
D
Q
Y
R
L
T
P
T
E
L
K
Q
K
Site 19
T435
H
A
L
L
M
Q
D
T
H
K
Q
L
L
E
R
Site 20
Y444
K
Q
L
L
E
R
G
Y
R
R
P
V
L
L
L
Site 21
Y518
M
V
A
G
A
N
F
Y
I
V
G
R
D
P
A
Site 22
T532
A
G
M
P
H
P
E
T
G
K
D
L
Y
E
P
Site 23
Y537
P
E
T
G
K
D
L
Y
E
P
S
H
G
A
K
Site 24
S540
G
K
D
L
Y
E
P
S
H
G
A
K
V
L
T
Site 25
Y574
K
K
K
K
R
M
D
Y
Y
D
S
E
H
H
E
Site 26
Y575
K
K
K
R
M
D
Y
Y
D
S
E
H
H
E
D
Site 27
T589
D
F
E
F
I
S
G
T
R
M
R
K
L
A
R
Site 28
T612
F
M
A
P
K
A
W
T
V
L
T
E
Y
Y
K
Site 29
T615
P
K
A
W
T
V
L
T
E
Y
Y
K
S
L
E
Site 30
Y617
A
W
T
V
L
T
E
Y
Y
K
S
L
E
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation