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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TREH
Full Name:
Trehalase
Alias:
Alpha,alpha-trehalase;Alpha,alpha-trehalose glucohydrolase
Type:
Mass (Da):
66568
Number AA:
583
UniProt ID:
O43280
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
P
P
C
E
S
E
I
Y
C
H
G
E
L
L
N
Site 2
Y48
Q
V
Q
M
A
K
L
Y
Q
D
D
K
Q
F
V
Site 3
T69
A
P
E
Q
V
L
Q
T
F
T
E
L
S
R
D
Site 4
S80
L
S
R
D
H
N
H
S
I
P
R
E
Q
L
Q
Site 5
T105
G
Q
E
L
Q
P
W
T
P
A
D
W
K
D
S
Site 6
S112
T
P
A
D
W
K
D
S
P
Q
F
L
Q
K
I
Site 7
S148
K
M
K
P
E
V
L
S
H
P
E
R
F
S
L
Site 8
S154
L
S
H
P
E
R
F
S
L
I
Y
S
E
H
P
Site 9
Y157
P
E
R
F
S
L
I
Y
S
E
H
P
F
I
V
Site 10
S158
E
R
F
S
L
I
Y
S
E
H
P
F
I
V
P
Site 11
Y178
E
F
Y
Y
W
D
S
Y
W
V
M
E
G
L
L
Site 12
T206
N
F
L
D
L
V
K
T
Y
G
H
V
P
N
G
Site 13
Y217
V
P
N
G
G
R
V
Y
Y
L
Q
R
S
Q
P
Site 14
Y218
P
N
G
G
R
V
Y
Y
L
Q
R
S
Q
P
P
Site 15
S222
R
V
Y
Y
L
Q
R
S
Q
P
P
L
L
T
L
Site 16
Y234
L
T
L
M
M
D
C
Y
L
T
H
T
N
D
T
Site 17
T259
A
L
E
L
D
F
W
T
K
N
R
T
V
S
V
Site 18
T263
D
F
W
T
K
N
R
T
V
S
V
S
L
E
G
Site 19
S265
W
T
K
N
R
T
V
S
V
S
L
E
G
K
N
Site 20
S267
K
N
R
T
V
S
V
S
L
E
G
K
N
Y
L
Site 21
Y273
V
S
L
E
G
K
N
Y
L
L
N
R
Y
Y
V
Site 22
Y278
K
N
Y
L
L
N
R
Y
Y
V
P
Y
G
G
P
Site 23
Y279
N
Y
L
L
N
R
Y
Y
V
P
Y
G
G
P
R
Site 24
Y282
L
N
R
Y
Y
V
P
Y
G
G
P
R
P
E
S
Site 25
S289
Y
G
G
P
R
P
E
S
Y
S
K
D
V
E
L
Site 26
S291
G
P
R
P
E
S
Y
S
K
D
V
E
L
A
D
Site 27
T299
K
D
V
E
L
A
D
T
L
P
E
G
D
R
E
Site 28
S318
E
L
K
A
G
A
E
S
G
W
D
F
S
S
R
Site 29
S323
A
E
S
G
W
D
F
S
S
R
W
L
I
G
G
Site 30
S324
E
S
G
W
D
F
S
S
R
W
L
I
G
G
P
Site 31
S335
I
G
G
P
N
P
N
S
L
S
G
I
R
T
S
Site 32
S337
G
P
N
P
N
S
L
S
G
I
R
T
S
K
L
Site 33
T341
N
S
L
S
G
I
R
T
S
K
L
V
P
V
D
Site 34
S361
C
Q
A
E
E
L
M
S
N
F
Y
S
R
L
G
Site 35
Y364
E
E
L
M
S
N
F
Y
S
R
L
G
N
D
S
Site 36
S365
E
L
M
S
N
F
Y
S
R
L
G
N
D
S
Q
Site 37
S371
Y
S
R
L
G
N
D
S
Q
A
T
K
Y
R
I
Site 38
Y376
N
D
S
Q
A
T
K
Y
R
I
L
R
S
Q
R
Site 39
S381
T
K
Y
R
I
L
R
S
Q
R
L
A
A
L
N
Site 40
Y402
Q
T
G
A
W
F
D
Y
D
L
E
K
K
K
K
Site 41
Y414
K
K
K
N
R
E
F
Y
P
S
N
L
T
P
L
Site 42
S416
K
N
R
E
F
Y
P
S
N
L
T
P
L
W
A
Site 43
Y438
V
A
D
K
A
L
K
Y
L
E
D
N
R
I
L
Site 44
T446
L
E
D
N
R
I
L
T
Y
Q
Y
G
I
P
T
Site 45
Y447
E
D
N
R
I
L
T
Y
Q
Y
G
I
P
T
S
Site 46
Y449
N
R
I
L
T
Y
Q
Y
G
I
P
T
S
L
Q
Site 47
S454
Y
Q
Y
G
I
P
T
S
L
Q
K
T
G
Q
Q
Site 48
T458
I
P
T
S
L
Q
K
T
G
Q
Q
W
D
F
P
Site 49
Y506
I
R
T
N
F
D
V
Y
S
Q
K
S
A
M
Y
Site 50
S507
R
T
N
F
D
V
Y
S
Q
K
S
A
M
Y
E
Site 51
Y516
K
S
A
M
Y
E
K
Y
D
V
S
N
G
G
Q
Site 52
S519
M
Y
E
K
Y
D
V
S
N
G
G
Q
P
G
G
Site 53
Y530
Q
P
G
G
G
G
E
Y
E
V
Q
E
G
F
G
Site 54
T555
D
R
Y
G
D
R
L
T
S
G
A
K
L
A
F
Site 55
S556
R
Y
G
D
R
L
T
S
G
A
K
L
A
F
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation