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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SART1
Full Name:
U4/U6.U5 tri-snRNP-associated protein 1
Alias:
Ara1; HSnu66; Small nuclear ribonucleoprotein 110kDa; SNRNP110; Snu66; SNUT1; Squamous cell carcinoma antigen recognised by T cells; Squamous cell carcinoma antigen recognized by T cells; Squamous cell carcinoma antigen recognized by T cells 1; U4/U6.U5 tri- snRNP-associated 110 kDa protein
Type:
Apoptosis protein
Mass (Da):
90255
Number AA:
800
UniProt ID:
O43290
International Prot ID:
IPI00021417
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005681
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0007050
GO:0008629
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
G
E
K
E
A
A
G
T
T
A
A
A
G
T
G
Site 2
T26
A
A
G
T
G
G
A
T
E
Q
P
P
R
H
R
Site 3
S42
H
K
K
H
K
H
R
S
G
G
S
G
G
S
G
Site 4
S56
G
G
E
R
R
K
R
S
R
E
R
G
G
E
R
Site 5
S65
E
R
G
G
E
R
G
S
G
R
R
G
A
E
A
Site 6
S77
A
E
A
E
A
R
S
S
T
H
G
R
E
R
S
Site 7
T78
E
A
E
A
R
S
S
T
H
G
R
E
R
S
Q
Site 8
S84
S
T
H
G
R
E
R
S
Q
A
E
P
S
E
R
Site 9
S89
E
R
S
Q
A
E
P
S
E
R
R
V
K
R
E
Site 10
Y102
R
E
K
R
D
D
G
Y
E
A
A
A
S
S
K
Site 11
S107
D
G
Y
E
A
A
A
S
S
K
T
S
S
G
D
Site 12
S108
G
Y
E
A
A
A
S
S
K
T
S
S
G
D
A
Site 13
S111
A
A
A
S
S
K
T
S
S
G
D
A
S
S
L
Site 14
S112
A
A
S
S
K
T
S
S
G
D
A
S
S
L
S
Site 15
S116
K
T
S
S
G
D
A
S
S
L
S
I
E
E
T
Site 16
S117
T
S
S
G
D
A
S
S
L
S
I
E
E
T
N
Site 17
S119
S
G
D
A
S
S
L
S
I
E
E
T
N
K
L
Site 18
T123
S
S
L
S
I
E
E
T
N
K
L
R
A
K
L
Site 19
T152
G
T
K
E
E
P
V
T
A
D
V
I
N
P
M
Site 20
T189
Q
K
L
G
K
I
K
T
L
G
E
D
D
P
W
Site 21
T200
D
D
P
W
L
D
D
T
A
A
W
I
E
R
S
Site 22
S234
M
D
Q
E
F
G
V
S
T
L
V
E
E
E
F
Site 23
Y249
G
Q
R
R
Q
D
L
Y
S
A
R
D
L
Q
G
Site 24
S250
Q
R
R
Q
D
L
Y
S
A
R
D
L
Q
G
L
Site 25
T258
A
R
D
L
Q
G
L
T
V
E
H
A
I
D
S
Site 26
S265
T
V
E
H
A
I
D
S
F
R
E
G
E
T
M
Site 27
T271
D
S
F
R
E
G
E
T
M
I
L
T
L
K
D
Site 28
T275
E
G
E
T
M
I
L
T
L
K
D
K
G
V
L
Site 29
Y313
L
R
K
K
K
P
D
Y
L
P
Y
A
E
D
E
Site 30
Y316
K
K
P
D
Y
L
P
Y
A
E
D
E
S
V
D
Site 31
S321
L
P
Y
A
E
D
E
S
V
D
D
L
A
Q
Q
Site 32
S332
L
A
Q
Q
K
P
R
S
I
L
S
K
Y
D
E
Site 33
S335
Q
K
P
R
S
I
L
S
K
Y
D
E
E
L
E
Site 34
Y337
P
R
S
I
L
S
K
Y
D
E
E
L
E
G
E
Site 35
S348
L
E
G
E
R
P
H
S
F
R
L
E
Q
G
G
Site 36
T356
F
R
L
E
Q
G
G
T
A
D
G
L
R
E
R
Site 37
S378
K
L
R
L
Q
A
Q
S
L
S
T
V
G
P
R
Site 38
S380
R
L
Q
A
Q
S
L
S
T
V
G
P
R
L
A
Site 39
T381
L
Q
A
Q
S
L
S
T
V
G
P
R
L
A
S
Site 40
S388
T
V
G
P
R
L
A
S
E
Y
L
T
P
E
E
Site 41
Y390
G
P
R
L
A
S
E
Y
L
T
P
E
E
M
V
Site 42
T392
R
L
A
S
E
Y
L
T
P
E
E
M
V
T
F
Site 43
T398
L
T
P
E
E
M
V
T
F
K
K
T
K
R
R
Site 44
T402
E
M
V
T
F
K
K
T
K
R
R
V
K
K
I
Site 45
T430
L
L
P
L
G
D
Q
T
Q
D
G
D
F
G
S
Site 46
S437
T
Q
D
G
D
F
G
S
R
L
R
G
R
G
R
Site 47
S448
G
R
G
R
R
R
V
S
E
V
E
E
E
K
E
Site 48
S463
P
V
P
Q
P
L
P
S
D
D
T
R
V
E
N
Site 49
T466
Q
P
L
P
S
D
D
T
R
V
E
N
M
D
I
Site 50
S474
R
V
E
N
M
D
I
S
D
E
E
E
G
G
A
Site 51
S486
G
G
A
P
P
P
G
S
P
Q
V
L
E
E
D
Site 52
S521
Q
L
Q
Q
L
R
D
S
G
E
K
V
V
E
I
Site 53
T562
A
T
S
E
F
C
R
T
L
G
E
I
P
T
Y
Site 54
Y569
T
L
G
E
I
P
T
Y
G
L
A
G
N
R
E
Site 55
S591
F
E
R
D
E
E
R
S
A
N
G
G
S
E
S
Site 56
S596
E
R
S
A
N
G
G
S
E
S
D
G
E
E
N
Site 57
S598
S
A
N
G
G
S
E
S
D
G
E
E
N
I
G
Site 58
T608
E
E
N
I
G
W
S
T
V
N
L
D
E
E
K
Site 59
S621
E
K
Q
Q
Q
D
F
S
A
S
S
T
T
I
L
Site 60
T625
Q
D
F
S
A
S
S
T
T
I
L
D
E
E
P
Site 61
S667
R
V
K
A
P
N
K
S
L
P
S
A
V
Y
C
Site 62
Y673
K
S
L
P
S
A
V
Y
C
I
E
D
K
M
A
Site 63
Y685
K
M
A
I
D
D
K
Y
S
R
R
E
E
Y
R
Site 64
S686
M
A
I
D
D
K
Y
S
R
R
E
E
Y
R
G
Site 65
Y691
K
Y
S
R
R
E
E
Y
R
G
F
T
Q
D
F
Site 66
T695
R
E
E
Y
R
G
F
T
Q
D
F
K
E
K
D
Site 67
Y704
D
F
K
E
K
D
G
Y
K
P
D
V
K
I
E
Site 68
Y712
K
P
D
V
K
I
E
Y
V
D
E
T
G
R
K
Site 69
T716
K
I
E
Y
V
D
E
T
G
R
K
L
T
P
K
Site 70
T721
D
E
T
G
R
K
L
T
P
K
E
A
F
R
Q
Site 71
S730
K
E
A
F
R
Q
L
S
H
R
F
H
G
K
G
Site 72
T743
K
G
S
G
K
M
K
T
E
R
R
M
K
K
L
Site 73
S760
E
A
L
L
K
K
M
S
S
S
D
T
P
L
G
Site 74
S761
A
L
L
K
K
M
S
S
S
D
T
P
L
G
T
Site 75
S762
L
L
K
K
M
S
S
S
D
T
P
L
G
T
V
Site 76
T764
K
K
M
S
S
S
D
T
P
L
G
T
V
A
L
Site 77
T768
S
S
D
T
P
L
G
T
V
A
L
L
Q
E
K
Site 78
T781
E
K
Q
K
A
Q
K
T
P
Y
I
V
L
S
G
Site 79
Y783
Q
K
A
Q
K
T
P
Y
I
V
L
S
G
S
G
Site 80
S787
K
T
P
Y
I
V
L
S
G
S
G
K
S
M
N
Site 81
S789
P
Y
I
V
L
S
G
S
G
K
S
M
N
A
N
Site 82
S792
V
L
S
G
S
G
K
S
M
N
A
N
T
I
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation