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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPAA1
Full Name:
Glycosylphosphatidylinositol anchor attachment 1 protein
Alias:
GAA1; glycosylphosphatidylinositol anchor attachment 1; glycosylphosphatidylinositol anchor attachment protein 1; GPAA1P anchor attachment protein 1 homolog (yeast); GPI anchor attachment protein 1; GPI transamidase subunit
Type:
Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Endoplasmic reticulum
Mass (Da):
67623
Number AA:
621
UniProt ID:
O43292
International Prot ID:
IPI00021594
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042765
Uniprot
OncoNet
Molecular Function:
GO:0015631
PhosphoSite+
KinaseNET
Biological Process:
GO:0016255
GO:0006461
GO:0006621
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T45
A
L
V
F
P
P
L
T
Q
R
T
Y
M
S
E
Site 2
Y49
P
P
L
T
Q
R
T
Y
M
S
E
N
A
M
G
Site 3
S51
L
T
Q
R
T
Y
M
S
E
N
A
M
G
S
T
Site 4
S84
F
A
A
H
R
K
K
S
G
A
L
P
V
A
W
Site 5
T95
P
V
A
W
L
E
R
T
M
R
S
V
G
L
E
Site 6
Y104
R
S
V
G
L
E
V
Y
T
Q
S
F
S
R
K
Site 7
T105
S
V
G
L
E
V
Y
T
Q
S
F
S
R
K
L
Site 8
S107
G
L
E
V
Y
T
Q
S
F
S
R
K
L
P
F
Site 9
S109
E
V
Y
T
Q
S
F
S
R
K
L
P
F
P
D
Site 10
T118
K
L
P
F
P
D
E
T
H
E
R
Y
M
V
S
Site 11
Y122
P
D
E
T
H
E
R
Y
M
V
S
G
T
N
V
Site 12
S154
T
V
P
C
G
S
D
S
T
N
S
Q
A
V
G
Site 13
T155
V
P
C
G
S
D
S
T
N
S
Q
A
V
G
L
Site 14
T205
A
Y
H
D
V
N
V
T
G
M
Q
S
S
P
L
Site 15
S210
N
V
T
G
M
Q
S
S
P
L
Q
G
R
A
G
Site 16
T267
Q
K
G
G
L
L
C
T
L
Q
G
K
L
Q
P
Site 17
T278
K
L
Q
P
E
D
W
T
S
L
D
G
P
L
Q
Site 18
S279
L
Q
P
E
D
W
T
S
L
D
G
P
L
Q
G
Site 19
S299
L
M
V
L
R
Q
A
S
G
R
P
H
G
S
H
Site 20
S305
A
S
G
R
P
H
G
S
H
G
L
F
L
R
Y
Site 21
T318
R
Y
R
V
E
A
L
T
L
R
G
I
N
S
F
Site 22
S324
L
T
L
R
G
I
N
S
F
R
Q
Y
K
Y
D
Site 23
Y328
G
I
N
S
F
R
Q
Y
K
Y
D
L
V
A
V
Site 24
Y330
N
S
F
R
Q
Y
K
Y
D
L
V
A
V
G
K
Site 25
S413
P
G
G
A
P
G
P
S
V
P
L
P
P
S
Q
Site 26
T482
G
L
A
L
P
H
N
T
H
R
V
V
S
T
Q
Site 27
S487
H
N
T
H
R
V
V
S
T
Q
A
P
D
R
G
Site 28
T488
N
T
H
R
V
V
S
T
Q
A
P
D
R
G
W
Site 29
S573
E
L
Q
E
A
P
L
S
L
A
E
G
W
Q
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation