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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TGFB1I1
Full Name:
Transforming growth factor beta-1-induced transcript 1 protein
Alias:
ARA55; Hydrogen peroxide-inducible clone 5; TGFB1L1; TGFI1; TSC-5
Type:
Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Mass (Da):
49814
Number AA:
461
UniProt ID:
O43294
International Prot ID:
IPI00396399
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005925
Uniprot
OncoNet
Molecular Function:
GO:0070411
GO:0050681
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0030521
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
E
D
L
D
A
L
L
S
D
L
E
T
T
T
S
Site 2
T13
A
L
L
S
D
L
E
T
T
T
S
H
M
P
R
Site 3
S16
S
D
L
E
T
T
T
S
H
M
P
R
S
G
A
Site 4
S21
T
T
S
H
M
P
R
S
G
A
P
K
E
R
P
Site 5
T33
E
R
P
A
E
P
L
T
P
P
P
S
Y
G
H
Site 6
S37
E
P
L
T
P
P
P
S
Y
G
H
Q
P
Q
T
Site 7
Y38
P
L
T
P
P
P
S
Y
G
H
Q
P
Q
T
G
Site 8
T44
S
Y
G
H
Q
P
Q
T
G
S
G
E
S
S
G
Site 9
S46
G
H
Q
P
Q
T
G
S
G
E
S
S
G
A
S
Site 10
S49
P
Q
T
G
S
G
E
S
S
G
A
S
G
D
K
Site 11
S50
Q
T
G
S
G
E
S
S
G
A
S
G
D
K
D
Site 12
S53
S
G
E
S
S
G
A
S
G
D
K
D
H
L
Y
Site 13
Y60
S
G
D
K
D
H
L
Y
S
T
V
C
K
P
R
Site 14
S61
G
D
K
D
H
L
Y
S
T
V
C
K
P
R
S
Site 15
T62
D
K
D
H
L
Y
S
T
V
C
K
P
R
S
P
Site 16
S68
S
T
V
C
K
P
R
S
P
K
P
A
A
P
A
Site 17
S81
A
A
P
P
F
S
S
S
S
G
V
L
G
T
G
Site 18
S82
A
A
P
P
F
S
S
S
S
G
V
L
G
T
G
Site 19
T103
L
L
Q
E
L
N
A
T
Q
F
N
I
T
D
E
Site 20
S113
N
I
T
D
E
I
M
S
Q
F
P
S
S
K
V
Site 21
S117
E
I
M
S
Q
F
P
S
S
K
V
A
S
G
E
Site 22
S118
I
M
S
Q
F
P
S
S
K
V
A
S
G
E
Q
Site 23
S122
F
P
S
S
K
V
A
S
G
E
Q
K
E
D
Q
Site 24
S130
G
E
Q
K
E
D
Q
S
E
D
K
K
R
P
S
Site 25
S137
S
E
D
K
K
R
P
S
L
P
S
S
P
S
P
Site 26
S140
K
K
R
P
S
L
P
S
S
P
S
P
G
L
P
Site 27
S141
K
R
P
S
L
P
S
S
P
S
P
G
L
P
K
Site 28
S143
P
S
L
P
S
S
P
S
P
G
L
P
K
A
S
Site 29
S150
S
P
G
L
P
K
A
S
A
T
S
A
T
L
E
Site 30
S164
E
L
D
R
L
M
A
S
L
S
D
F
R
V
Q
Site 31
S166
D
R
L
M
A
S
L
S
D
F
R
V
Q
N
H
Site 32
S177
V
Q
N
H
L
P
A
S
G
P
T
Q
P
P
V
Site 33
S186
P
T
Q
P
P
V
V
S
S
T
N
E
G
S
P
Site 34
S187
T
Q
P
P
V
V
S
S
T
N
E
G
S
P
S
Site 35
T188
Q
P
P
V
V
S
S
T
N
E
G
S
P
S
P
Site 36
S192
V
S
S
T
N
E
G
S
P
S
P
P
E
P
T
Site 37
S194
S
T
N
E
G
S
P
S
P
P
E
P
T
G
K
Site 38
T199
S
P
S
P
P
E
P
T
G
K
G
S
L
D
T
Site 39
S203
P
E
P
T
G
K
G
S
L
D
T
M
L
G
L
Site 40
T206
T
G
K
G
S
L
D
T
M
L
G
L
L
Q
S
Site 41
S216
G
L
L
Q
S
D
L
S
R
R
G
V
P
T
Q
Site 42
T222
L
S
R
R
G
V
P
T
Q
A
K
G
L
C
G
Site 43
S230
Q
A
K
G
L
C
G
S
C
N
K
P
I
A
G
Site 44
S265
S
T
A
L
G
G
S
S
F
F
E
K
D
G
A
Site 45
Y279
A
P
F
C
P
E
C
Y
F
E
R
F
S
P
R
Site 46
Y333
H
E
R
E
G
R
P
Y
C
R
R
D
F
L
Q
Site 47
S359
P
I
L
D
N
Y
I
S
A
L
S
A
L
W
H
Site 48
S380
R
E
C
F
A
P
F
S
G
G
S
F
F
E
H
Site 49
S383
F
A
P
F
S
G
G
S
F
F
E
H
E
G
R
Site 50
S403
H
F
H
A
R
R
G
S
L
C
A
T
C
G
L
Site 51
S418
P
V
T
G
R
C
V
S
A
L
G
R
R
F
H
Site 52
T439
T
F
C
L
R
P
L
T
K
G
S
F
Q
E
R
Site 53
S442
L
R
P
L
T
K
G
S
F
Q
E
R
A
G
K
Site 54
Y451
Q
E
R
A
G
K
P
Y
C
Q
P
C
F
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation