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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CEP110
Full Name:
Centrosomal protein CP110
Alias:
CE110
Type:
Cell cycle regulation
Mass (Da):
113424
Number AA:
1012
UniProt ID:
O43303
International Prot ID:
IPI00011933
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005814
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007099
GO:0032465
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
Y
E
K
F
C
E
K
S
L
A
R
I
Q
E
A
Site 2
S21
R
I
Q
E
A
S
L
S
T
E
S
F
L
P
A
Site 3
S24
E
A
S
L
S
T
E
S
F
L
P
A
Q
S
E
Site 4
S30
E
S
F
L
P
A
Q
S
E
S
I
S
L
I
R
Site 5
S34
P
A
Q
S
E
S
I
S
L
I
R
F
H
G
V
Site 6
S98
V
R
K
A
P
N
A
S
D
F
D
Q
W
E
M
Site 7
T107
F
D
Q
W
E
M
E
T
V
Y
S
N
S
E
V
Site 8
Y109
Q
W
E
M
E
T
V
Y
S
N
S
E
V
R
N
Site 9
S110
W
E
M
E
T
V
Y
S
N
S
E
V
R
N
L
Site 10
S112
M
E
T
V
Y
S
N
S
E
V
R
N
L
N
V
Site 11
T122
R
N
L
N
V
P
A
T
F
P
N
S
F
P
S
Site 12
S126
V
P
A
T
F
P
N
S
F
P
S
H
T
E
H
Site 13
S129
T
F
P
N
S
F
P
S
H
T
E
H
S
T
A
Site 14
S165
G
I
D
L
A
R
D
S
E
G
F
N
S
P
K
Site 15
S170
R
D
S
E
G
F
N
S
P
K
Q
C
D
S
S
Site 16
S176
N
S
P
K
Q
C
D
S
S
N
I
S
H
V
E
Site 17
S177
S
P
K
Q
C
D
S
S
N
I
S
H
V
E
N
Site 18
S180
Q
C
D
S
S
N
I
S
H
V
E
N
E
A
F
Site 19
T190
E
N
E
A
F
P
K
T
S
S
A
T
P
Q
E
Site 20
S191
N
E
A
F
P
K
T
S
S
A
T
P
Q
E
T
Site 21
S192
E
A
F
P
K
T
S
S
A
T
P
Q
E
T
L
Site 22
T194
F
P
K
T
S
S
A
T
P
Q
E
T
L
I
S
Site 23
T198
S
S
A
T
P
Q
E
T
L
I
S
D
G
P
F
Site 24
S201
T
P
Q
E
T
L
I
S
D
G
P
F
S
V
N
Site 25
S206
L
I
S
D
G
P
F
S
V
N
E
Q
Q
D
L
Site 26
S227
I
P
D
P
Y
V
M
S
L
Q
N
L
M
K
K
Site 27
Y238
L
M
K
K
S
K
E
Y
I
E
R
E
Q
S
R
Site 28
S244
E
Y
I
E
R
E
Q
S
R
R
S
L
R
G
S
Site 29
S247
E
R
E
Q
S
R
R
S
L
R
G
S
I
N
R
Site 30
S251
S
R
R
S
L
R
G
S
I
N
R
I
V
N
E
Site 31
S259
I
N
R
I
V
N
E
S
H
L
D
K
E
H
D
Site 32
S287
L
T
G
K
H
C
V
S
V
I
P
D
K
P
S
Site 33
S294
S
V
I
P
D
K
P
S
L
N
K
S
N
V
L
Site 34
S298
D
K
P
S
L
N
K
S
N
V
L
L
Q
G
A
Site 35
S306
N
V
L
L
Q
G
A
S
T
Q
A
S
S
M
S
Site 36
S310
Q
G
A
S
T
Q
A
S
S
M
S
M
P
V
L
Site 37
T333
P
I
R
T
G
H
P
T
V
L
E
S
N
S
D
Site 38
S337
G
H
P
T
V
L
E
S
N
S
D
F
K
V
I
Site 39
S339
P
T
V
L
E
S
N
S
D
F
K
V
I
P
T
Site 40
T346
S
D
F
K
V
I
P
T
F
V
T
E
N
N
V
Site 41
S356
T
E
N
N
V
I
K
S
L
T
G
S
Y
A
K
Site 42
S360
V
I
K
S
L
T
G
S
Y
A
K
L
P
S
P
Site 43
S366
G
S
Y
A
K
L
P
S
P
E
P
S
M
S
P
Site 44
S370
K
L
P
S
P
E
P
S
M
S
P
K
M
H
R
Site 45
S372
P
S
P
E
P
S
M
S
P
K
M
H
R
R
R
Site 46
S380
P
K
M
H
R
R
R
S
R
T
S
S
A
C
H
Site 47
T382
M
H
R
R
R
S
R
T
S
S
A
C
H
I
L
Site 48
S383
H
R
R
R
S
R
T
S
S
A
C
H
I
L
I
Site 49
S384
R
R
R
S
R
T
S
S
A
C
H
I
L
I
N
Site 50
S400
P
I
N
A
C
E
L
S
P
K
G
K
E
Q
A
Site 51
T415
M
D
L
I
I
Q
D
T
D
E
N
T
N
V
P
Site 52
T419
I
Q
D
T
D
E
N
T
N
V
P
E
I
M
P
Site 53
Y441
G
V
C
S
S
K
V
Y
V
G
K
N
T
S
E
Site 54
S447
V
Y
V
G
K
N
T
S
E
V
K
E
D
V
V
Site 55
S458
E
D
V
V
L
G
K
S
N
Q
V
C
Q
S
S
Site 56
T474
N
H
L
E
N
K
V
T
H
G
L
V
T
V
E
Site 57
T485
V
T
V
E
G
Q
L
T
S
D
E
R
G
A
H
Site 58
S486
T
V
E
G
Q
L
T
S
D
E
R
G
A
H
I
Site 59
S510
K
L
H
E
P
Y
A
S
S
Q
C
I
A
S
P
Site 60
S511
L
H
E
P
Y
A
S
S
Q
C
I
A
S
P
N
Site 61
S523
S
P
N
F
G
T
V
S
G
L
K
P
A
S
M
Site 62
S529
V
S
G
L
K
P
A
S
M
L
E
K
N
C
S
Site 63
S536
S
M
L
E
K
N
C
S
L
Q
T
E
L
N
K
Site 64
S544
L
Q
T
E
L
N
K
S
Y
D
V
K
N
P
S
Site 65
Y545
Q
T
E
L
N
K
S
Y
D
V
K
N
P
S
P
Site 66
S551
S
Y
D
V
K
N
P
S
P
L
L
M
Q
N
Q
Site 67
T566
N
T
R
Q
Q
M
D
T
P
M
V
S
C
G
N
Site 68
S580
N
E
Q
F
L
D
N
S
F
E
K
V
K
R
R
Site 69
Y602
L
Q
K
E
N
C
P
Y
V
I
T
S
G
I
T
Site 70
Y621
Q
H
L
P
E
K
R
Y
P
K
G
S
G
F
V
Site 71
S625
E
K
R
Y
P
K
G
S
G
F
V
N
K
N
K
Site 72
S637
K
N
K
M
L
G
T
S
S
K
E
S
E
E
L
Site 73
S638
N
K
M
L
G
T
S
S
K
E
S
E
E
L
L
Site 74
S641
L
G
T
S
S
K
E
S
E
E
L
L
K
S
K
Site 75
S647
E
S
E
E
L
L
K
S
K
M
L
A
F
E
E
Site 76
S668
E
Q
H
A
Q
Q
L
S
L
L
I
A
E
Q
E
Site 77
S719
E
L
E
W
R
K
I
S
D
S
S
L
L
E
T
Site 78
S721
E
W
R
K
I
S
D
S
S
L
L
E
T
M
L
Site 79
T726
S
D
S
S
L
L
E
T
M
L
S
Q
A
D
S
Site 80
S729
S
L
L
E
T
M
L
S
Q
A
D
S
L
H
T
Site 81
S733
T
M
L
S
Q
A
D
S
L
H
T
S
N
S
N
Site 82
S737
Q
A
D
S
L
H
T
S
N
S
N
S
S
G
F
Site 83
S739
D
S
L
H
T
S
N
S
N
S
S
G
F
T
N
Site 84
S741
L
H
T
S
N
S
N
S
S
G
F
T
N
S
A
Site 85
T745
N
S
N
S
S
G
F
T
N
S
A
M
Q
Y
S
Site 86
S747
N
S
S
G
F
T
N
S
A
M
Q
Y
S
F
V
Site 87
Y751
F
T
N
S
A
M
Q
Y
S
F
V
S
A
N
E
Site 88
S752
T
N
S
A
M
Q
Y
S
F
V
S
A
N
E
A
Site 89
Y762
S
A
N
E
A
P
F
Y
L
W
G
S
S
T
S
Site 90
S767
P
F
Y
L
W
G
S
S
T
S
G
L
T
K
L
Site 91
S775
T
S
G
L
T
K
L
S
V
T
R
P
F
G
R
Site 92
T785
R
P
F
G
R
A
K
T
R
W
S
Q
V
F
S
Site 93
S788
G
R
A
K
T
R
W
S
Q
V
F
S
L
E
I
Site 94
S792
T
R
W
S
Q
V
F
S
L
E
I
Q
A
K
F
Site 95
T811
A
V
A
K
G
F
L
T
R
R
L
M
Q
T
D
Site 96
T817
L
T
R
R
L
M
Q
T
D
K
L
K
Q
L
R
Site 97
T826
K
L
K
Q
L
R
Q
T
V
K
D
T
M
E
F
Site 98
T830
L
R
Q
T
V
K
D
T
M
E
F
I
R
S
F
Site 99
S836
D
T
M
E
F
I
R
S
F
Q
S
E
A
P
L
Site 100
S839
E
F
I
R
S
F
Q
S
E
A
P
L
K
R
G
Site 101
S884
M
D
A
A
E
R
M
S
I
L
H
H
D
R
E
Site 102
S906
R
Q
M
D
K
M
K
S
P
R
V
A
L
S
A
Site 103
S912
K
S
P
R
V
A
L
S
A
A
T
Q
K
S
L
Site 104
S918
L
S
A
A
T
Q
K
S
L
D
R
K
K
Y
M
Site 105
Y924
K
S
L
D
R
K
K
Y
M
K
A
A
E
M
G
Site 106
S944
F
L
V
K
Q
N
P
S
E
T
R
V
L
Q
P
Site 107
S964
A
P
V
H
R
L
L
S
R
Q
G
T
P
K
T
Site 108
T968
R
L
L
S
R
Q
G
T
P
K
T
S
V
K
G
Site 109
T971
S
R
Q
G
T
P
K
T
S
V
K
G
V
V
Q
Site 110
S984
V
Q
N
R
Q
K
P
S
Q
S
R
V
P
N
R
Site 111
S986
N
R
Q
K
P
S
Q
S
R
V
P
N
R
V
P
Site 112
S995
V
P
N
R
V
P
V
S
G
V
Y
A
G
K
I
Site 113
Y998
R
V
P
V
S
G
V
Y
A
G
K
I
Q
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation