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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZSCAN12
Full Name:
Zinc finger and SCAN domain-containing protein 12
Alias:
Zinc finger protein 305;Zinc finger protein 96
Type:
Mass (Da):
70222
Number AA:
604
UniProt ID:
O43309
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y26
V
K
I
E
E
E
K
Y
T
T
R
Q
D
W
D
Site 2
T27
K
I
E
E
E
K
Y
T
T
R
Q
D
W
D
L
Site 3
T39
W
D
L
R
K
N
N
T
H
S
R
E
V
F
R
Site 4
S41
L
R
K
N
N
T
H
S
R
E
V
F
R
Q
Y
Site 5
Y48
S
R
E
V
F
R
Q
Y
F
R
Q
F
C
Y
Q
Site 6
Y54
Q
Y
F
R
Q
F
C
Y
Q
E
T
S
G
P
R
Site 7
S58
Q
F
C
Y
Q
E
T
S
G
P
R
E
A
L
S
Site 8
S65
S
G
P
R
E
A
L
S
R
L
R
E
L
C
H
Site 9
T79
H
Q
W
L
R
P
E
T
H
T
K
E
Q
I
L
Site 10
T81
W
L
R
P
E
T
H
T
K
E
Q
I
L
E
L
Site 11
S113
V
Q
E
Q
H
P
E
S
G
E
E
V
V
T
V
Site 12
T119
E
S
G
E
E
V
V
T
V
L
E
D
L
E
R
Site 13
S136
D
E
P
G
E
Q
V
S
V
H
T
G
E
Q
E
Site 14
T149
Q
E
M
F
L
Q
E
T
V
R
L
R
K
E
G
Site 15
S159
L
R
K
E
G
E
P
S
M
S
L
Q
S
M
K
Site 16
S161
K
E
G
E
P
S
M
S
L
Q
S
M
K
A
Q
Site 17
S164
E
P
S
M
S
L
Q
S
M
K
A
Q
P
K
Y
Site 18
Y171
S
M
K
A
Q
P
K
Y
E
S
P
E
L
E
S
Site 19
S173
K
A
Q
P
K
Y
E
S
P
E
L
E
S
Q
Q
Site 20
S200
G
N
L
K
Q
E
V
S
E
E
M
E
P
H
G
Site 21
S211
E
P
H
G
K
T
S
S
K
F
E
N
D
M
S
Site 22
S218
S
K
F
E
N
D
M
S
K
S
A
R
C
G
E
Site 23
S220
F
E
N
D
M
S
K
S
A
R
C
G
E
T
R
Site 24
T233
T
R
E
P
E
E
I
T
E
E
P
S
A
C
S
Site 25
S254
T
C
D
E
N
G
V
S
L
T
E
N
S
D
H
Site 26
S259
G
V
S
L
T
E
N
S
D
H
T
E
H
Q
R
Site 27
T262
L
T
E
N
S
D
H
T
E
H
Q
R
I
C
P
Site 28
Y274
I
C
P
G
E
E
S
Y
G
C
D
D
C
G
K
Site 29
S284
D
D
C
G
K
A
F
S
Q
H
S
H
L
I
E
Site 30
S287
G
K
A
F
S
Q
H
S
H
L
I
E
H
Q
R
Site 31
T297
I
E
H
Q
R
I
H
T
G
D
R
P
Y
K
C
Site 32
Y302
I
H
T
G
D
R
P
Y
K
C
E
E
C
G
K
Site 33
T315
G
K
A
F
R
G
R
T
V
L
I
R
H
K
I
Site 34
T325
I
R
H
K
I
I
H
T
G
E
K
P
Y
K
C
Site 35
Y330
I
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 36
S343
G
K
A
F
G
R
W
S
A
L
N
Q
H
Q
R
Site 37
T353
N
Q
H
Q
R
L
H
T
G
E
K
H
Y
H
C
Site 38
Y358
L
H
T
G
E
K
H
Y
H
C
N
D
C
G
K
Site 39
S368
N
D
C
G
K
A
F
S
Q
K
A
G
L
F
H
Site 40
Y386
I
H
T
R
D
K
P
Y
Q
C
T
Q
C
N
K
Site 41
S394
Q
C
T
Q
C
N
K
S
F
S
R
R
S
I
L
Site 42
S396
T
Q
C
N
K
S
F
S
R
R
S
I
L
T
Q
Site 43
S399
N
K
S
F
S
R
R
S
I
L
T
Q
H
Q
G
Site 44
T402
F
S
R
R
S
I
L
T
Q
H
Q
G
V
H
T
Site 45
Y414
V
H
T
G
A
K
P
Y
E
C
N
E
C
G
K
Site 46
Y425
E
C
G
K
A
F
V
Y
N
S
S
L
V
S
H
Site 47
S427
G
K
A
F
V
Y
N
S
S
L
V
S
H
Q
E
Site 48
S428
K
A
F
V
Y
N
S
S
L
V
S
H
Q
E
I
Site 49
S431
V
Y
N
S
S
L
V
S
H
Q
E
I
H
H
K
Site 50
Y442
I
H
H
K
E
K
C
Y
Q
C
K
E
C
G
K
Site 51
S450
Q
C
K
E
C
G
K
S
F
S
Q
S
G
L
I
Site 52
S452
K
E
C
G
K
S
F
S
Q
S
G
L
I
Q
H
Site 53
S454
C
G
K
S
F
S
Q
S
G
L
I
Q
H
Q
R
Site 54
T464
I
Q
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 55
S483
K
A
F
I
Q
R
T
S
L
T
E
H
Q
R
I
Site 56
T485
F
I
Q
R
T
S
L
T
E
H
Q
R
I
H
T
Site 57
T492
T
E
H
Q
R
I
H
T
G
E
R
P
Y
K
C
Site 58
Y497
I
H
T
G
E
R
P
Y
K
C
D
K
C
G
K
Site 59
T507
D
K
C
G
K
A
F
T
Q
R
S
V
L
T
E
Site 60
S510
G
K
A
F
T
Q
R
S
V
L
T
E
H
Q
R
Site 61
Y525
I
H
T
G
E
R
P
Y
K
C
D
E
C
G
N
Site 62
T538
G
N
A
F
R
G
I
T
S
L
I
Q
H
Q
R
Site 63
T548
I
Q
H
Q
R
I
H
T
G
E
K
P
Y
Q
C
Site 64
Y553
I
H
T
G
E
K
P
Y
Q
C
D
E
C
G
K
Site 65
T568
A
F
R
Q
R
K
K
T
S
Y
K
E
I
L
L
Site 66
Y570
R
Q
R
K
K
T
S
Y
K
E
I
L
L
K
N
Site 67
S579
E
I
L
L
K
N
H
S
E
P
Q
A
G
V
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation