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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAX4
Full Name:
Paired box protein Pax-4
Alias:
Type:
Mass (Da):
37833
Number AA:
350
UniProt ID:
O43316
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
H
Q
D
G
I
S
S
M
N
Q
L
G
G
L
Site 2
S44
G
M
R
P
C
D
I
S
R
I
L
K
V
S
N
Site 3
Y61
V
S
K
I
L
G
R
Y
Y
R
T
G
V
L
E
Site 4
Y62
S
K
I
L
G
R
Y
Y
R
T
G
V
L
E
P
Site 5
T64
I
L
G
R
Y
Y
R
T
G
V
L
E
P
K
G
Site 6
S75
E
P
K
G
I
G
G
S
K
P
R
L
A
T
P
Site 7
T81
G
S
K
P
R
L
A
T
P
P
V
V
A
R
I
Site 8
T114
L
C
A
E
G
L
C
T
Q
D
K
T
P
S
V
Site 9
T118
G
L
C
T
Q
D
K
T
P
S
V
S
S
I
N
Site 10
S120
C
T
Q
D
K
T
P
S
V
S
S
I
N
R
V
Site 11
S123
D
K
T
P
S
V
S
S
I
N
R
V
L
R
A
Site 12
T140
E
D
Q
G
L
P
C
T
R
L
R
S
P
A
V
Site 13
S157
P
A
V
L
T
P
H
S
G
S
E
T
P
R
G
Site 14
S159
V
L
T
P
H
S
G
S
E
T
P
R
G
T
H
Site 15
T161
T
P
H
S
G
S
E
T
P
R
G
T
H
P
G
Site 16
T165
G
S
E
T
P
R
G
T
H
P
G
T
G
H
R
Site 17
T169
P
R
G
T
H
P
G
T
G
H
R
N
R
T
I
Site 18
T175
G
T
G
H
R
N
R
T
I
F
S
P
S
Q
A
Site 19
S178
H
R
N
R
T
I
F
S
P
S
Q
A
E
A
L
Site 20
S180
N
R
T
I
F
S
P
S
Q
A
E
A
L
E
K
Site 21
Y194
K
E
F
Q
R
G
Q
Y
P
D
S
V
A
R
G
Site 22
S197
Q
R
G
Q
Y
P
D
S
V
A
R
G
K
L
A
Site 23
T205
V
A
R
G
K
L
A
T
A
T
S
L
P
E
D
Site 24
S208
G
K
L
A
T
A
T
S
L
P
E
D
T
V
R
Site 25
T213
A
T
S
L
P
E
D
T
V
R
V
W
F
S
N
Site 26
T245
P
G
A
S
Q
G
L
T
V
P
R
V
A
P
G
Site 27
S255
R
V
A
P
G
I
I
S
A
Q
Q
S
P
G
S
Site 28
S259
G
I
I
S
A
Q
Q
S
P
G
S
V
P
T
A
Site 29
S262
S
A
Q
Q
S
P
G
S
V
P
T
A
A
L
P
Site 30
S292
T
A
P
E
R
C
L
S
D
T
P
P
K
A
C
Site 31
T294
P
E
R
C
L
S
D
T
P
P
K
A
C
L
K
Site 32
T342
I
G
G
A
G
K
A
T
P
T
H
F
S
H
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation