KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF749
Full Name:
Zinc finger protein 749
Alias:
FLJ16360; ZN749
Type:
Mass (Da):
80610
Number AA:
UniProt ID:
O43361
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
H
L
A
E
H
D
G
T
H
P
E
Q
G
L
Y
Site 2
Y25
T
H
P
E
Q
G
L
Y
T
C
A
A
E
H
D
Site 3
S46
I
R
E
K
L
T
R
S
D
E
W
R
P
S
F
Site 4
S52
R
S
D
E
W
R
P
S
F
V
N
H
S
A
H
Site 5
T66
H
V
G
E
R
N
F
T
C
T
Q
G
G
K
D
Site 6
T68
G
E
R
N
F
T
C
T
Q
G
G
K
D
F
T
Site 7
S77
G
G
K
D
F
T
A
S
S
D
L
L
Q
Q
Q
Site 8
S78
G
K
D
F
T
A
S
S
D
L
L
Q
Q
Q
V
Site 9
T96
G
W
K
L
Y
R
D
T
Q
D
G
E
A
F
Q
Site 10
S111
G
E
Q
N
D
F
N
S
S
Q
G
G
K
D
F
Site 11
S112
E
Q
N
D
F
N
S
S
Q
G
G
K
D
F
C
Site 12
T130
G
L
F
E
H
Q
K
T
H
N
G
E
R
P
Y
Site 13
Y137
T
H
N
G
E
R
P
Y
E
F
S
E
C
G
E
Site 14
S140
G
E
R
P
Y
E
F
S
E
C
G
E
L
F
R
Site 15
Y148
E
C
G
E
L
F
R
Y
N
S
N
L
I
K
Y
Site 16
S150
G
E
L
F
R
Y
N
S
N
L
I
K
Y
Q
Q
Site 17
Y155
Y
N
S
N
L
I
K
Y
Q
Q
N
H
A
G
E
Site 18
Y165
N
H
A
G
E
R
P
Y
E
G
T
E
Y
G
K
Site 19
T168
G
E
R
P
Y
E
G
T
E
Y
G
K
T
F
I
Site 20
Y170
R
P
Y
E
G
T
E
Y
G
K
T
F
I
R
K
Site 21
T173
E
G
T
E
Y
G
K
T
F
I
R
K
S
N
L
Site 22
S178
G
K
T
F
I
R
K
S
N
L
V
Q
H
Q
K
Site 23
S193
I
H
S
E
G
F
L
S
K
R
S
D
P
I
E
Site 24
S196
E
G
F
L
S
K
R
S
D
P
I
E
H
Q
E
Site 25
S206
I
E
H
Q
E
I
L
S
R
P
T
P
Y
E
C
Site 26
T209
Q
E
I
L
S
R
P
T
P
Y
E
C
T
Q
C
Site 27
Y211
I
L
S
R
P
T
P
Y
E
C
T
Q
C
G
K
Site 28
Y239
T
H
T
G
E
Q
P
Y
E
C
N
K
C
G
K
Site 29
Y250
K
C
G
K
F
F
M
Y
N
S
K
L
I
R
H
Site 30
Y267
V
H
T
G
E
R
R
Y
E
C
S
E
C
G
K
Site 31
S279
C
G
K
L
F
M
D
S
F
T
L
G
R
H
Q
Site 32
T281
K
L
F
M
D
S
F
T
L
G
R
H
Q
R
V
Site 33
T290
G
R
H
Q
R
V
H
T
G
E
R
P
F
E
C
Site 34
S308
G
K
F
F
S
H
R
S
T
L
N
M
H
Q
R
Site 35
T309
K
F
F
S
H
R
S
T
L
N
M
H
Q
R
V
Site 36
Y323
V
H
A
G
K
R
L
Y
K
C
S
E
C
G
K
Site 37
S326
G
K
R
L
Y
K
C
S
E
C
G
K
A
F
S
Site 38
S333
S
E
C
G
K
A
F
S
L
K
H
N
V
V
Q
Site 39
Y351
I
H
T
G
E
R
P
Y
E
C
T
E
C
E
K
Site 40
T354
G
E
R
P
Y
E
C
T
E
C
E
K
A
F
V
Site 41
S364
E
K
A
F
V
R
K
S
H
L
V
Q
H
Q
K
Site 42
T374
V
Q
H
Q
K
I
H
T
D
A
F
S
K
R
S
Site 43
S378
K
I
H
T
D
A
F
S
K
R
S
D
L
I
Q
Site 44
Y396
I
D
I
R
P
R
P
Y
T
C
S
E
C
G
K
Site 45
T397
D
I
R
P
R
P
Y
T
C
S
E
C
G
K
A
Site 46
S399
R
P
R
P
Y
T
C
S
E
C
G
K
A
F
L
Site 47
Y424
I
H
T
G
E
R
P
Y
E
C
T
Q
C
A
K
Site 48
S437
A
K
A
F
V
R
K
S
H
L
V
Q
H
E
K
Site 49
T447
V
Q
H
E
K
I
H
T
D
A
F
S
K
R
S
Site 50
Y469
I
D
L
R
P
R
P
Y
V
C
S
E
C
G
K
Site 51
S472
R
P
R
P
Y
V
C
S
E
C
G
K
A
F
L
Site 52
T480
E
C
G
K
A
F
L
T
Q
A
H
L
D
G
H
Site 53
T492
D
G
H
Q
K
I
Q
T
G
E
R
R
Y
E
C
Site 54
Y497
I
Q
T
G
E
R
R
Y
E
C
N
E
C
G
K
Site 55
Y510
G
K
F
F
L
D
S
Y
K
L
V
I
H
Q
R
Site 56
T520
V
I
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 57
Y536
K
C
G
K
F
F
R
Y
R
C
T
L
S
R
H
Site 58
T539
K
F
F
R
Y
R
C
T
L
S
R
H
Q
K
V
Site 59
Y553
V
H
T
G
E
R
P
Y
E
C
S
E
C
G
K
Site 60
Y566
G
K
F
F
R
D
S
Y
K
L
I
I
H
Q
R
Site 61
T576
I
I
H
Q
R
V
H
T
G
E
K
P
Y
E
C
Site 62
Y581
V
H
T
G
E
K
P
Y
E
C
S
N
C
G
K
Site 63
Y592
N
C
G
K
F
L
R
Y
R
S
T
F
I
K
H
Site 64
S594
G
K
F
L
R
Y
R
S
T
F
I
K
H
H
K
Site 65
T595
K
F
L
R
Y
R
S
T
F
I
K
H
H
K
V
Site 66
S612
G
E
K
P
H
E
C
S
K
C
R
E
L
F
R
Site 67
T620
K
C
R
E
L
F
R
T
K
S
S
L
I
I
H
Site 68
S622
R
E
L
F
R
T
K
S
S
L
I
I
H
Q
Q
Site 69
S623
E
L
F
R
T
K
S
S
L
I
I
H
Q
Q
S
Site 70
S630
S
L
I
I
H
Q
Q
S
H
T
G
E
S
P
F
Site 71
S635
Q
Q
S
H
T
G
E
S
P
F
K
L
R
E
C
Site 72
T657
N
T
G
Q
R
Q
K
T
H
T
G
E
R
S
Y
Site 73
T659
G
Q
R
Q
K
T
H
T
G
E
R
S
Y
E
C
Site 74
S663
K
T
H
T
G
E
R
S
Y
E
C
G
E
S
S
Site 75
Y664
T
H
T
G
E
R
S
Y
E
C
G
E
S
S
K
Site 76
S669
R
S
Y
E
C
G
E
S
S
K
V
F
K
Y
N
Site 77
Y675
E
S
S
K
V
F
K
Y
N
S
S
L
I
K
H
Site 78
S677
S
K
V
F
K
Y
N
S
S
L
I
K
H
Q
I
Site 79
S678
K
V
F
K
Y
N
S
S
L
I
K
H
Q
I
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation