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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOXA3
Full Name:
Homeobox protein Hox-A3
Alias:
HOX1; Hox-1.5-like; HOX1E; HXA3
Type:
Nucleus protein
Mass (Da):
46369
Number AA:
443
UniProt ID:
O43365
International Prot ID:
IPI00012050
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
Q
K
A
T
Y
Y
D
S
S
A
I
Y
G
Site 2
S9
Q
K
A
T
Y
Y
D
S
S
A
I
Y
G
G
Y
Site 3
S10
K
A
T
Y
Y
D
S
S
A
I
Y
G
G
Y
P
Site 4
Y13
Y
Y
D
S
S
A
I
Y
G
G
Y
P
Y
Q
A
Site 5
Y16
S
S
A
I
Y
G
G
Y
P
Y
Q
A
A
N
G
Site 6
Y33
Y
N
A
N
Q
Q
P
Y
P
A
S
A
A
L
G
Site 7
S36
N
Q
Q
P
Y
P
A
S
A
A
L
G
A
D
G
Site 8
Y45
A
L
G
A
D
G
E
Y
H
R
P
A
C
S
L
Site 9
S51
E
Y
H
R
P
A
C
S
L
Q
S
P
S
S
A
Site 10
S54
R
P
A
C
S
L
Q
S
P
S
S
A
G
G
H
Site 11
S56
A
C
S
L
Q
S
P
S
S
A
G
G
H
P
K
Site 12
S57
C
S
L
Q
S
P
S
S
A
G
G
H
P
K
A
Site 13
T74
L
S
E
A
C
L
R
T
L
S
A
P
P
S
Q
Site 14
S76
E
A
C
L
R
T
L
S
A
P
P
S
Q
P
P
Site 15
S80
R
T
L
S
A
P
P
S
Q
P
P
S
L
G
E
Site 16
S84
A
P
P
S
Q
P
P
S
L
G
E
P
P
L
H
Site 17
T115
A
P
Q
P
P
A
P
T
P
A
A
P
P
P
P
Site 18
S123
P
A
A
P
P
P
P
S
S
A
S
P
P
Q
N
Site 19
S124
A
A
P
P
P
P
S
S
A
S
P
P
Q
N
A
Site 20
S126
P
P
P
P
S
S
A
S
P
P
Q
N
A
S
N
Site 21
S132
A
S
P
P
Q
N
A
S
N
N
P
T
P
A
N
Site 22
T136
Q
N
A
S
N
N
P
T
P
A
N
A
A
K
S
Site 23
S143
T
P
A
N
A
A
K
S
P
L
L
N
S
P
T
Site 24
S148
A
K
S
P
L
L
N
S
P
T
V
A
K
Q
I
Site 25
T166
M
K
E
S
R
Q
N
T
K
Q
K
T
S
S
S
Site 26
T170
R
Q
N
T
K
Q
K
T
S
S
S
S
S
G
E
Site 27
S171
Q
N
T
K
Q
K
T
S
S
S
S
S
G
E
S
Site 28
S172
N
T
K
Q
K
T
S
S
S
S
S
G
E
S
C
Site 29
S173
T
K
Q
K
T
S
S
S
S
S
G
E
S
C
A
Site 30
S175
Q
K
T
S
S
S
S
S
G
E
S
C
A
G
D
Site 31
S178
S
S
S
S
S
G
E
S
C
A
G
D
K
S
P
Site 32
S184
E
S
C
A
G
D
K
S
P
P
G
Q
A
S
S
Site 33
S191
S
P
P
G
Q
A
S
S
K
R
A
R
T
A
Y
Site 34
T196
A
S
S
K
R
A
R
T
A
Y
T
S
A
Q
L
Site 35
Y198
S
K
R
A
R
T
A
Y
T
S
A
Q
L
V
E
Site 36
S200
R
A
R
T
A
Y
T
S
A
Q
L
V
E
L
E
Site 37
Y215
K
E
F
H
F
N
R
Y
L
C
R
P
R
R
V
Site 38
T231
M
A
N
L
L
N
L
T
E
R
Q
I
K
I
W
Site 39
Y246
F
Q
N
R
R
M
K
Y
K
K
D
Q
K
G
K
Site 40
T257
Q
K
G
K
G
M
L
T
S
S
G
G
Q
S
P
Site 41
S258
K
G
K
G
M
L
T
S
S
G
G
Q
S
P
S
Site 42
S259
G
K
G
M
L
T
S
S
G
G
Q
S
P
S
R
Site 43
S263
L
T
S
S
G
G
Q
S
P
S
R
S
P
V
P
Site 44
S265
S
S
G
G
Q
S
P
S
R
S
P
V
P
P
G
Site 45
S267
G
G
Q
S
P
S
R
S
P
V
P
P
G
A
G
Site 46
Y276
V
P
P
G
A
G
G
Y
L
N
S
M
H
S
L
Site 47
S279
G
A
G
G
Y
L
N
S
M
H
S
L
V
N
S
Site 48
S282
G
Y
L
N
S
M
H
S
L
V
N
S
V
P
Y
Site 49
S286
S
M
H
S
L
V
N
S
V
P
Y
E
P
Q
S
Site 50
Y289
S
L
V
N
S
V
P
Y
E
P
Q
S
P
P
P
Site 51
S293
S
V
P
Y
E
P
Q
S
P
P
P
F
S
K
P
Site 52
S298
P
Q
S
P
P
P
F
S
K
P
P
Q
G
T
Y
Site 53
Y305
S
K
P
P
Q
G
T
Y
G
L
P
P
A
S
Y
Site 54
S311
T
Y
G
L
P
P
A
S
Y
P
A
S
L
P
S
Site 55
Y312
Y
G
L
P
P
A
S
Y
P
A
S
L
P
S
C
Site 56
S315
P
P
A
S
Y
P
A
S
L
P
S
C
A
P
P
Site 57
S318
S
Y
P
A
S
L
P
S
C
A
P
P
P
P
P
Site 58
Y329
P
P
P
P
Q
K
R
Y
T
A
A
G
A
G
A
Site 59
T330
P
P
P
Q
K
R
Y
T
A
A
G
A
G
A
G
Site 60
T339
A
G
A
G
A
G
G
T
P
D
Y
D
P
H
A
Site 61
Y342
G
A
G
G
T
P
D
Y
D
P
H
A
H
G
L
Site 62
S354
H
G
L
Q
G
N
G
S
Y
G
T
P
H
I
Q
Site 63
Y355
G
L
Q
G
N
G
S
Y
G
T
P
H
I
Q
G
Site 64
T357
Q
G
N
G
S
Y
G
T
P
H
I
Q
G
S
P
Site 65
S363
G
T
P
H
I
Q
G
S
P
V
F
V
G
G
S
Site 66
S370
S
P
V
F
V
G
G
S
Y
V
E
P
M
S
N
Site 67
Y371
P
V
F
V
G
G
S
Y
V
E
P
M
S
N
S
Site 68
S376
G
S
Y
V
E
P
M
S
N
S
G
P
A
L
F
Site 69
S393
T
H
L
P
H
A
A
S
G
A
M
D
Y
G
G
Site 70
S406
G
G
A
G
P
L
G
S
G
H
H
H
G
P
G
Site 71
T420
G
P
G
E
P
H
P
T
Y
T
D
L
T
G
H
Site 72
Y421
P
G
E
P
H
P
T
Y
T
D
L
T
G
H
H
Site 73
T422
G
E
P
H
P
T
Y
T
D
L
T
G
H
H
P
Site 74
T425
H
P
T
Y
T
D
L
T
G
H
H
P
S
Q
G
Site 75
S430
D
L
T
G
H
H
P
S
Q
G
R
I
Q
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation