KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WDR62
Full Name:
WD repeat-containing protein 62
Alias:
C19orf14; DKFZP434J046; FLJ33298; Putative DKFZp434J046; WD repeat 62; WD repeat domain 62
Type:
Adaptor/scaffold protein
Mass (Da):
165962
Number AA:
1518
UniProt ID:
O43379
International Prot ID:
IPI00798158
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
A
V
G
S
G
G
Y
A
R
N
D
Site 2
S32
V
P
A
R
R
G
Q
S
S
P
P
P
A
P
P
Site 3
S33
P
A
R
R
G
Q
S
S
P
P
P
A
P
P
I
Site 4
T46
P
I
C
L
R
R
R
T
R
L
S
T
A
S
E
Site 5
S49
L
R
R
R
T
R
L
S
T
A
S
E
E
T
V
Site 6
T50
R
R
R
T
R
L
S
T
A
S
E
E
T
V
Q
Site 7
S52
R
T
R
L
S
T
A
S
E
E
T
V
Q
N
R
Site 8
T55
L
S
T
A
S
E
E
T
V
Q
N
R
V
S
L
Site 9
S61
E
T
V
Q
N
R
V
S
L
E
K
V
L
G
I
Site 10
T77
A
Q
N
S
S
G
L
T
C
D
P
G
T
G
H
Site 11
T109
K
Q
Q
H
I
F
N
T
A
R
K
S
L
S
A
Site 12
S115
N
T
A
R
K
S
L
S
A
L
A
F
S
P
D
Site 13
Y125
A
F
S
P
D
G
K
Y
I
V
T
G
E
N
G
Site 14
Y156
A
E
M
L
G
H
K
Y
G
V
A
C
V
A
F
Site 15
S164
G
V
A
C
V
A
F
S
P
N
M
K
H
I
V
Site 16
S194
K
K
D
I
V
V
A
S
N
K
V
S
C
R
V
Site 17
S205
S
C
R
V
I
A
L
S
F
S
E
D
S
S
Y
Site 18
S211
L
S
F
S
E
D
S
S
Y
F
V
T
V
G
N
Site 19
Y212
S
F
S
E
D
S
S
Y
F
V
T
V
G
N
R
Site 20
T215
E
D
S
S
Y
F
V
T
V
G
N
R
H
V
R
Site 21
S236
S
T
E
T
K
V
T
S
T
V
P
L
V
G
R
Site 22
S268
G
R
G
R
M
A
G
S
T
F
C
V
S
Y
S
Site 23
T269
R
G
R
M
A
G
S
T
F
C
V
S
Y
S
G
Site 24
Y336
A
N
L
P
K
P
H
Y
L
G
V
D
V
A
Q
Site 25
S348
V
A
Q
G
L
E
P
S
F
L
F
H
R
K
A
Site 26
S399
N
R
V
G
K
V
W
S
E
L
F
H
S
S
Y
Site 27
Y406
S
E
L
F
H
S
S
Y
V
W
N
V
E
V
Y
Site 28
Y413
Y
V
W
N
V
E
V
Y
P
E
F
E
D
Q
R
Site 29
S425
D
Q
R
A
C
L
P
S
G
S
F
L
T
C
S
Site 30
S427
R
A
C
L
P
S
G
S
F
L
T
C
S
S
D
Site 31
S432
S
G
S
F
L
T
C
S
S
D
N
T
I
R
F
Site 32
S445
R
F
W
N
L
D
S
S
P
D
S
H
W
Q
K
Site 33
Y464
N
T
L
L
K
V
V
Y
V
E
N
D
I
Q
H
Site 34
S476
I
Q
H
L
Q
D
M
S
H
F
P
D
R
G
S
Site 35
S483
S
H
F
P
D
R
G
S
E
N
G
T
P
M
D
Site 36
T487
D
R
G
S
E
N
G
T
P
M
D
V
K
A
G
Site 37
S501
G
V
R
V
M
Q
V
S
P
D
G
Q
H
L
A
Site 38
S509
P
D
G
Q
H
L
A
S
G
D
R
S
G
N
L
Site 39
S513
H
L
A
S
G
D
R
S
G
N
L
R
I
H
E
Site 40
Y542
A
E
V
L
C
L
E
Y
S
K
P
E
T
G
L
Site 41
S543
E
V
L
C
L
E
Y
S
K
P
E
T
G
L
T
Site 42
T547
L
E
Y
S
K
P
E
T
G
L
T
L
L
A
S
Site 43
T550
S
K
P
E
T
G
L
T
L
L
A
S
A
S
R
Site 44
T575
K
N
Y
N
L
E
Q
T
L
D
D
H
S
S
S
Site 45
S580
E
Q
T
L
D
D
H
S
S
S
I
T
A
I
K
Site 46
S581
Q
T
L
D
D
H
S
S
S
I
T
A
I
K
F
Site 47
S582
T
L
D
D
H
S
S
S
I
T
A
I
K
F
A
Site 48
T584
D
D
H
S
S
S
I
T
A
I
K
F
A
G
N
Site 49
S598
N
R
D
I
Q
M
I
S
C
G
A
D
K
S
I
Site 50
S604
I
S
C
G
A
D
K
S
I
Y
F
R
S
A
Q
Site 51
Y606
C
G
A
D
K
S
I
Y
F
R
S
A
Q
Q
G
Site 52
S609
D
K
S
I
Y
F
R
S
A
Q
Q
G
S
D
G
Site 53
S614
F
R
S
A
Q
Q
G
S
D
G
L
H
F
V
R
Site 54
Y632
V
A
E
K
T
T
L
Y
D
M
D
I
D
I
T
Site 55
Y642
D
I
D
I
T
Q
K
Y
V
A
V
A
C
Q
D
Site 56
Y655
Q
D
R
N
V
R
V
Y
N
T
V
N
G
K
Q
Site 57
T657
R
N
V
R
V
Y
N
T
V
N
G
K
Q
K
K
Site 58
Y666
N
G
K
Q
K
K
C
Y
K
G
S
Q
G
D
E
Site 59
S669
Q
K
K
C
Y
K
G
S
Q
G
D
E
G
S
L
Site 60
S675
G
S
Q
G
D
E
G
S
L
L
K
V
H
V
D
Site 61
S691
S
G
T
F
L
A
T
S
C
S
D
K
S
I
S
Site 62
S698
S
C
S
D
K
S
I
S
V
I
D
F
Y
S
G
Site 63
T719
F
G
H
S
E
I
I
T
S
M
K
F
T
Y
D
Site 64
S737
L
I
T
V
S
G
D
S
C
V
F
I
W
H
L
Site 65
T781
S
G
H
P
R
Q
D
T
Y
V
S
T
P
S
E
Site 66
Y782
G
H
P
R
Q
D
T
Y
V
S
T
P
S
E
I
Site 67
S784
P
R
Q
D
T
Y
V
S
T
P
S
E
I
H
S
Site 68
T785
R
Q
D
T
Y
V
S
T
P
S
E
I
H
S
L
Site 69
S787
D
T
Y
V
S
T
P
S
E
I
H
S
L
S
P
Site 70
S791
S
T
P
S
E
I
H
S
L
S
P
G
E
Q
T
Site 71
S793
P
S
E
I
H
S
L
S
P
G
E
Q
T
E
D
Site 72
T814
E
P
E
E
M
L
K
T
P
S
K
D
S
L
D
Site 73
S819
L
K
T
P
S
K
D
S
L
D
P
D
P
R
C
Site 74
T829
P
D
P
R
C
L
L
T
N
G
K
L
P
L
W
Site 75
Y858
A
F
H
A
K
R
S
Y
Q
P
H
G
R
W
A
Site 76
T875
A
G
Q
E
P
L
K
T
I
L
D
A
Q
D
L
Site 77
Y885
D
A
Q
D
L
D
C
Y
F
T
P
M
K
P
E
Site 78
T887
Q
D
L
D
C
Y
F
T
P
M
K
P
E
S
L
Site 79
S893
F
T
P
M
K
P
E
S
L
E
N
S
I
L
D
Site 80
S897
K
P
E
S
L
E
N
S
I
L
D
S
L
E
P
Site 81
S901
L
E
N
S
I
L
D
S
L
E
P
Q
S
L
A
Site 82
S906
L
D
S
L
E
P
Q
S
L
A
S
L
L
S
E
Site 83
S909
L
E
P
Q
S
L
A
S
L
L
S
E
S
E
S
Site 84
S912
Q
S
L
A
S
L
L
S
E
S
E
S
P
Q
E
Site 85
S914
L
A
S
L
L
S
E
S
E
S
P
Q
E
A
G
Site 86
S916
S
L
L
S
E
S
E
S
P
Q
E
A
G
R
G
Site 87
S926
E
A
G
R
G
H
P
S
F
L
P
Q
Q
K
E
Site 88
S935
L
P
Q
Q
K
E
S
S
E
A
S
E
L
I
L
Site 89
S938
Q
K
E
S
S
E
A
S
E
L
I
L
Y
S
L
Site 90
S944
A
S
E
L
I
L
Y
S
L
E
A
E
V
T
V
Site 91
T950
Y
S
L
E
A
E
V
T
V
T
G
T
D
S
Q
Site 92
T952
L
E
A
E
V
T
V
T
G
T
D
S
Q
Y
C
Site 93
S956
V
T
V
T
G
T
D
S
Q
Y
C
R
K
E
V
Site 94
Y958
V
T
G
T
D
S
Q
Y
C
R
K
E
V
E
A
Site 95
S974
P
G
D
Q
Q
G
D
S
Y
L
R
V
S
S
D
Site 96
Y975
G
D
Q
Q
G
D
S
Y
L
R
V
S
S
D
S
Site 97
S979
G
D
S
Y
L
R
V
S
S
D
S
P
K
D
Q
Site 98
S980
D
S
Y
L
R
V
S
S
D
S
P
K
D
Q
S
Site 99
S982
Y
L
R
V
S
S
D
S
P
K
D
Q
S
P
P
Site 100
S987
S
D
S
P
K
D
Q
S
P
P
E
D
S
G
E
Site 101
S992
D
Q
S
P
P
E
D
S
G
E
S
E
A
D
L
Site 102
S995
P
P
E
D
S
G
E
S
E
A
D
L
E
C
S
Site 103
S1002
S
E
A
D
L
E
C
S
F
A
A
I
H
S
P
Site 104
S1008
C
S
F
A
A
I
H
S
P
A
P
P
P
D
P
Site 105
T1021
D
P
A
P
R
F
A
T
S
L
P
H
F
P
G
Site 106
S1022
P
A
P
R
F
A
T
S
L
P
H
F
P
G
C
Site 107
S1038
G
P
T
E
D
E
L
S
L
P
E
G
P
S
V
Site 108
S1044
L
S
L
P
E
G
P
S
V
P
S
S
S
L
P
Site 109
S1047
P
E
G
P
S
V
P
S
S
S
L
P
Q
T
P
Site 110
S1048
E
G
P
S
V
P
S
S
S
L
P
Q
T
P
E
Site 111
S1049
G
P
S
V
P
S
S
S
L
P
Q
T
P
E
Q
Site 112
T1053
P
S
S
S
L
P
Q
T
P
E
Q
E
K
F
L
Site 113
T1066
F
L
R
H
H
F
E
T
L
T
E
S
P
C
R
Site 114
T1068
R
H
H
F
E
T
L
T
E
S
P
C
R
A
L
Site 115
S1070
H
F
E
T
L
T
E
S
P
C
R
A
L
G
D
Site 116
S1093
H
F
F
N
P
R
L
S
I
S
T
Q
F
L
S
Site 117
T1096
N
P
R
L
S
I
S
T
Q
F
L
S
S
L
Q
Site 118
S1100
S
I
S
T
Q
F
L
S
S
L
Q
K
A
S
R
Site 119
S1101
I
S
T
Q
F
L
S
S
L
Q
K
A
S
R
F
Site 120
T1109
L
Q
K
A
S
R
F
T
H
T
F
P
P
R
A
Site 121
T1111
K
A
S
R
F
T
H
T
F
P
P
R
A
T
Q
Site 122
T1117
H
T
F
P
P
R
A
T
Q
C
L
V
K
S
P
Site 123
S1123
A
T
Q
C
L
V
K
S
P
E
V
K
L
M
D
Site 124
S1134
K
L
M
D
R
G
G
S
Q
P
R
A
G
T
G
Site 125
T1140
G
S
Q
P
R
A
G
T
G
Y
A
S
P
D
R
Site 126
Y1142
Q
P
R
A
G
T
G
Y
A
S
P
D
R
T
H
Site 127
S1144
R
A
G
T
G
Y
A
S
P
D
R
T
H
V
L
Site 128
T1148
G
Y
A
S
P
D
R
T
H
V
L
A
A
G
K
Site 129
S1181
A
S
C
V
P
A
S
S
V
L
P
T
D
R
N
Site 130
T1185
P
A
S
S
V
L
P
T
D
R
N
L
P
T
P
Site 131
T1191
P
T
D
R
N
L
P
T
P
T
S
A
P
T
P
Site 132
T1193
D
R
N
L
P
T
P
T
S
A
P
T
P
G
L
Site 133
S1194
R
N
L
P
T
P
T
S
A
P
T
P
G
L
A
Site 134
T1197
P
T
P
T
S
A
P
T
P
G
L
A
Q
G
V
Site 135
S1208
A
Q
G
V
H
A
P
S
T
C
S
Y
M
E
A
Site 136
T1209
Q
G
V
H
A
P
S
T
C
S
Y
M
E
A
T
Site 137
S1211
V
H
A
P
S
T
C
S
Y
M
E
A
T
A
S
Site 138
Y1212
H
A
P
S
T
C
S
Y
M
E
A
T
A
S
S
Site 139
S1218
S
Y
M
E
A
T
A
S
S
R
A
R
I
S
R
Site 140
S1219
Y
M
E
A
T
A
S
S
R
A
R
I
S
R
S
Site 141
S1224
A
S
S
R
A
R
I
S
R
S
I
S
L
G
D
Site 142
S1226
S
R
A
R
I
S
R
S
I
S
L
G
D
S
E
Site 143
S1228
A
R
I
S
R
S
I
S
L
G
D
S
E
G
P
Site 144
S1232
R
S
I
S
L
G
D
S
E
G
P
I
V
A
T
Site 145
T1239
S
E
G
P
I
V
A
T
L
A
Q
P
L
R
R
Site 146
S1248
A
Q
P
L
R
R
P
S
S
V
G
E
L
A
S
Site 147
S1249
Q
P
L
R
R
P
S
S
V
G
E
L
A
S
L
Site 148
S1255
S
S
V
G
E
L
A
S
L
G
Q
E
L
Q
A
Site 149
T1264
G
Q
E
L
Q
A
I
T
T
A
T
T
P
S
L
Site 150
T1268
Q
A
I
T
T
A
T
T
P
S
L
D
S
E
G
Site 151
S1270
I
T
T
A
T
T
P
S
L
D
S
E
G
Q
E
Site 152
S1282
G
Q
E
P
A
L
R
S
W
G
N
H
E
A
R
Site 153
T1295
A
R
A
N
L
R
L
T
L
S
S
A
C
D
G
Site 154
S1337
S
A
L
R
L
H
G
S
A
F
R
P
S
L
P
Site 155
S1342
H
G
S
A
F
R
P
S
L
P
A
P
E
S
P
Site 156
S1348
P
S
L
P
A
P
E
S
P
G
L
P
A
H
P
Site 157
S1356
P
G
L
P
A
H
P
S
N
P
Q
L
P
E
A
Site 158
S1388
A
L
G
L
F
Q
G
S
P
A
R
W
S
E
P
Site 159
S1393
Q
G
S
P
A
R
W
S
E
P
W
V
P
V
E
Site 160
S1405
P
V
E
A
L
P
P
S
P
L
E
L
S
R
V
Site 161
S1410
P
P
S
P
L
E
L
S
R
V
G
N
I
L
H
Site 162
T1421
N
I
L
H
R
L
Q
T
T
F
Q
E
A
L
D
Site 163
S1436
L
Y
R
V
L
V
S
S
G
Q
V
D
T
G
Q
Site 164
T1441
V
S
S
G
Q
V
D
T
G
Q
Q
Q
A
R
T
Site 165
T1448
T
G
Q
Q
Q
A
R
T
E
L
V
S
T
F
L
Site 166
S1479
A
P
A
Q
A
L
P
S
P
G
P
P
S
P
P
Site 167
S1484
L
P
S
P
G
P
P
S
P
P
T
L
Y
P
L
Site 168
T1487
P
G
P
P
S
P
P
T
L
Y
P
L
A
S
P
Site 169
Y1489
P
P
S
P
P
T
L
Y
P
L
A
S
P
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation