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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TPD52L2
Full Name:
Tumor protein D54
Alias:
D54; HD54; TPD54; Tumor protein D54
Type:
Unknown function
Mass (Da):
22238
Number AA:
206
UniProt ID:
O43399
International Prot ID:
IPI00306825
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0042127
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
D
S
A
G
Q
D
I
N
L
Site 2
S12
G
Q
D
I
N
L
N
S
P
N
K
G
L
L
S
Site 3
S19
S
P
N
K
G
L
L
S
D
S
M
T
D
V
P
Site 4
S21
N
K
G
L
L
S
D
S
M
T
D
V
P
V
D
Site 5
T23
G
L
L
S
D
S
M
T
D
V
P
V
D
T
G
Site 6
T29
M
T
D
V
P
V
D
T
G
V
A
A
R
T
P
Site 7
T35
D
T
G
V
A
A
R
T
P
A
V
E
G
L
T
Site 8
T42
T
P
A
V
E
G
L
T
E
A
E
E
E
E
L
Site 9
S84
L
K
R
R
L
G
L
S
T
L
G
E
L
K
Q
Site 10
T85
K
R
R
L
G
L
S
T
L
G
E
L
K
Q
N
Site 11
S94
G
E
L
K
Q
N
L
S
R
S
W
H
D
V
Q
Site 12
S96
L
K
Q
N
L
S
R
S
W
H
D
V
Q
V
S
Site 13
Y106
D
V
Q
V
S
S
A
Y
V
K
T
S
E
K
L
Site 14
Y126
K
V
T
Q
S
D
L
Y
K
K
T
Q
E
T
L
Site 15
T129
Q
S
D
L
Y
K
K
T
Q
E
T
L
S
Q
A
Site 16
S134
K
K
T
Q
E
T
L
S
Q
A
G
Q
K
T
S
Site 17
T140
L
S
Q
A
G
Q
K
T
S
A
A
L
S
T
V
Site 18
S141
S
Q
A
G
Q
K
T
S
A
A
L
S
T
V
G
Site 19
S145
Q
K
T
S
A
A
L
S
T
V
G
S
A
I
S
Site 20
S149
A
A
L
S
T
V
G
S
A
I
S
R
K
L
G
Site 21
S161
K
L
G
D
M
R
N
S
A
T
F
K
S
F
E
Site 22
T163
G
D
M
R
N
S
A
T
F
K
S
F
E
D
R
Site 23
S166
R
N
S
A
T
F
K
S
F
E
D
R
V
G
T
Site 24
T173
S
F
E
D
R
V
G
T
I
K
S
K
V
V
G
Site 25
S176
D
R
V
G
T
I
K
S
K
V
V
G
D
R
E
Site 26
S186
V
G
D
R
E
N
G
S
D
N
L
P
S
S
A
Site 27
S191
N
G
S
D
N
L
P
S
S
A
G
S
G
D
K
Site 28
S192
G
S
D
N
L
P
S
S
A
G
S
G
D
K
P
Site 29
S195
N
L
P
S
S
A
G
S
G
D
K
P
L
S
D
Site 30
S201
G
S
G
D
K
P
L
S
D
P
A
P
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation