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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBX1
Full Name:
T-box transcription factor TBX1
Alias:
CAFS; CTHM; DGCR; DGS; DORV; T-box 1; T-box 1 transcription factor C
Type:
Transcription factor
Mass (Da):
43133
Number AA:
398
UniProt ID:
O43435
International Prot ID:
IPI00395723
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0042803
GO:0043565
PhosphoSite+
KinaseNET
Biological Process:
GO:0048703
GO:0007507
GO:0060017
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
T
R
D
M
E
A
F
T
A
S
S
L
S
S
L
Site 2
S32
G
G
F
P
G
A
A
S
P
G
A
D
P
Y
G
Site 3
Y38
A
S
P
G
A
D
P
Y
G
P
R
E
P
P
P
Site 4
Y50
P
P
P
P
P
P
R
Y
D
P
C
A
A
A
A
Site 5
Y70
P
P
P
P
P
H
A
Y
P
F
A
P
A
A
G
Site 6
S81
P
A
A
G
A
A
T
S
A
A
A
E
P
E
G
Site 7
Y170
V
P
V
D
D
K
R
Y
R
Y
A
F
H
S
S
Site 8
Y172
V
D
D
K
R
Y
R
Y
A
F
H
S
S
S
W
Site 9
S176
R
Y
R
Y
A
F
H
S
S
S
W
L
V
A
G
Site 10
S178
R
Y
A
F
H
S
S
S
W
L
V
A
G
K
A
Site 11
T189
A
G
K
A
D
P
A
T
P
G
R
V
H
Y
H
Site 12
Y195
A
T
P
G
R
V
H
Y
H
P
D
S
P
A
K
Site 13
S199
R
V
H
Y
H
P
D
S
P
A
K
G
A
Q
W
Site 14
Y237
I
L
N
S
M
H
R
Y
Q
P
R
F
H
V
V
Site 15
Y245
Q
P
R
F
H
V
V
Y
V
D
P
R
K
D
S
Site 16
S252
Y
V
D
P
R
K
D
S
E
K
Y
A
E
E
N
Site 17
Y255
P
R
K
D
S
E
K
Y
A
E
E
N
F
K
T
Site 18
T262
Y
A
E
E
N
F
K
T
F
V
F
E
E
T
R
Site 19
T271
V
F
E
E
T
R
F
T
A
V
T
A
Y
Q
N
Site 20
T274
E
T
R
F
T
A
V
T
A
Y
Q
N
H
R
I
Site 21
Y276
R
F
T
A
V
T
A
Y
Q
N
H
R
I
T
Q
Site 22
T282
A
Y
Q
N
H
R
I
T
Q
L
K
I
A
S
N
Site 23
S316
P
G
A
L
P
L
M
S
A
F
A
R
S
R
N
Site 24
S321
L
M
S
A
F
A
R
S
R
N
P
V
A
S
P
Site 25
S327
R
S
R
N
P
V
A
S
P
T
Q
P
S
G
T
Site 26
T329
R
N
P
V
A
S
P
T
Q
P
S
G
T
E
K
Site 27
S332
V
A
S
P
T
Q
P
S
G
T
E
K
G
G
H
Site 28
T354
K
A
E
T
S
R
N
T
P
E
R
E
V
E
L
Site 29
T392
Q
G
L
V
A
G
R
T
A
G
D
R
L
C
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation