PhosphoNET

           
Protein Info 
   
Short Name:  KLF4
Full Name:  Krueppel-like factor 4
Alias:  Endothelial kruppel-like zinc finger; Epithelial zinc-finger, EZF; EZF; GKLF; Gut- enriched krueppel-like; Krueppel-like 4
Type:  Uncharacterized protein
Mass (Da):  50078
Number AA:  470
UniProt ID:  O43474
International Prot ID:  IPI00012531
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0016563  GO:0003700  GO:0016564 PhosphoSite+ KinaseNET
Biological Process:  GO:0007500  GO:0045892  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S25PSFSTFASGPAGREK
Site 2T33GPAGREKTLRQAGAP
Site 3T96APLPRRETEEFNDLL
Site 4S112LDFILSNSLTHPPES
Site 5S119SLTHPPESVAATVSS
Site 6T123PPESVAATVSSSASA
Site 7S125ESVAATVSSSASASS
Site 8S129ATVSSSASASSSSSP
Site 9S131VSSSASASSSSSPSS
Site 10S132SSSASASSSSSPSSS
Site 11S133SSASASSSSSPSSSG
Site 12S134SASASSSSSPSSSGP
Site 13S135ASASSSSSPSSSGPA
Site 14S137ASSSSSPSSSGPASA
Site 15S138SSSSSPSSSGPASAP
Site 16S139SSSSPSSSGPASAPS
Site 17S143PSSSGPASAPSTCSF
Site 18S146SGPASAPSTCSFTYP
Site 19S149ASAPSTCSFTYPIRA
Site 20Y152PSTCSFTYPIRAGND
Site 21Y173GTGGGLLYGRESAPP
Site 22S177GLLYGRESAPPPTAP
Site 23T182RESAPPPTAPFNLAD
Site 24Y212RPELDPVYIPPQQPQ
Site 25S234GKFVLKASLSAPGSE
Site 26S236FVLKASLSAPGSEYG
Site 27S240ASLSAPGSEYGSPSV
Site 28Y242LSAPGSEYGSPSVIS
Site 29S244APGSEYGSPSVISVS
Site 30S246GSEYGSPSVISVSKG
Site 31S249SKGSPDGSHPVVVAP
Site 32S251SPSVISVSKGSPDGS
Site 33S254VISVSKGSPDGSHPV
Site 34S258SKGSPDGSHPVVVAP
Site 35S284IKQEAVSSCTHLGAG
Site 36S295LGAGPPLSNGHRPAA
Site 37T316RQLPSRTTPTLGLEE
Site 38S326LGLEEVLSSRDCHPA
Site 39S327GLEEVLSSRDCHPAL
Site 40Y348HPHPGPNYPSFLPDQ
Site 41S350HPGPNYPSFLPDQMQ
Site 42Y365PQVPPLHYQGQSRGF
Site 43T394GTHGMMLTPPSSPLE
Site 44S407LELMPPGSCMPEEPK
Site 45S421KPKRGRRSWPRKRTA
Site 46T427RSWPRKRTATHTCDY
Site 47T429WPRKRTATHTCDYAG
Site 48T431RKRTATHTCDYAGCG
Site 49Y434TATHTCDYAGCGKTY
Site 50T440DYAGCGKTYTKSSHL
Site 51Y441YAGCGKTYTKSSHLK
Site 52T442AGCGKTYTKSSHLKA
Site 53S444CGKTYTKSSHLKAHL
Site 54S445GKTYTKSSHLKAHLR
Site 55T453HLKAHLRTHTGEKPY
Site 56T455KAHLRTHTGEKPYHC
Site 57T478FARSDELTRHYRKHT
Site 58Y481SDELTRHYRKHTGHR
Site 59T485TRHYRKHTGHRPFQC
Site 60S500QKCDRAFSRSDHLAL
Site 61S502CDRAFSRSDHLALHM
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation