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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC26A4
Full Name:
Pendrin
Alias:
Sodium-independent chloride/iodide transporter;Solute carrier family 26 member 4
Type:
Mass (Da):
85723
Number AA:
780
UniProt ID:
O43511
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
E
P
P
Q
L
P
E
Y
S
C
S
Y
M
V
S
Site 2
S17
P
P
Q
L
P
E
Y
S
C
S
Y
M
V
S
R
Site 3
S19
Q
L
P
E
Y
S
C
S
Y
M
V
S
R
P
V
Site 4
Y20
L
P
E
Y
S
C
S
Y
M
V
S
R
P
V
Y
Site 5
S23
Y
S
C
S
Y
M
V
S
R
P
V
Y
S
E
L
Site 6
Y27
Y
M
V
S
R
P
V
Y
S
E
L
A
F
Q
Q
Site 7
T45
R
R
L
Q
E
R
K
T
L
R
E
S
L
A
K
Site 8
S49
E
R
K
T
L
R
E
S
L
A
K
C
C
S
C
Site 9
S55
E
S
L
A
K
C
C
S
C
S
R
K
R
A
F
Site 10
Y78
I
L
E
W
L
P
K
Y
R
V
K
E
W
L
L
Site 11
S137
F
G
T
S
R
H
I
S
V
G
P
F
P
V
V
Site 12
S145
V
G
P
F
P
V
V
S
L
M
V
G
S
V
V
Site 13
S164
P
D
E
H
F
L
V
S
S
S
N
G
T
V
L
Site 14
S166
E
H
F
L
V
S
S
S
N
G
T
V
L
N
T
Site 15
T178
L
N
T
T
M
I
D
T
A
A
R
D
T
A
R
Site 16
Y375
G
K
V
Y
A
T
K
Y
D
Y
T
I
D
G
N
Site 17
Y377
V
Y
A
T
K
Y
D
Y
T
I
D
G
N
Q
E
Site 18
S448
L
L
E
P
L
Q
K
S
V
L
A
A
V
V
I
Site 19
S523
P
S
W
N
G
L
G
S
I
P
S
T
D
I
Y
Site 20
S526
N
G
L
G
S
I
P
S
T
D
I
Y
K
S
T
Site 21
T527
G
L
G
S
I
P
S
T
D
I
Y
K
S
T
K
Site 22
Y530
S
I
P
S
T
D
I
Y
K
S
T
K
N
Y
K
Site 23
S532
P
S
T
D
I
Y
K
S
T
K
N
Y
K
N
I
Site 24
Y536
I
Y
K
S
T
K
N
Y
K
N
I
E
E
P
Q
Site 25
Y556
R
F
S
S
P
I
F
Y
G
N
V
D
G
F
K
Site 26
Y578
G
F
D
A
I
R
V
Y
N
K
R
L
K
A
L
Site 27
S594
K
I
Q
K
L
I
K
S
G
Q
L
R
A
T
K
Site 28
T600
K
S
G
Q
L
R
A
T
K
N
G
I
I
S
D
Site 29
S606
A
T
K
N
G
I
I
S
D
A
V
S
T
N
N
Site 30
S610
G
I
I
S
D
A
V
S
T
N
N
A
F
E
P
Site 31
S642
E
I
Q
V
D
W
N
S
E
L
P
V
K
V
N
Site 32
Y691
Q
R
I
D
V
N
V
Y
F
A
S
L
Q
D
Y
Site 33
Y698
Y
F
A
S
L
Q
D
Y
V
I
E
K
L
E
Q
Site 34
T717
D
D
N
I
R
K
D
T
F
F
L
T
V
H
D
Site 35
Y728
T
V
H
D
A
I
L
Y
L
Q
N
Q
V
K
S
Site 36
S735
Y
L
Q
N
Q
V
K
S
Q
E
G
Q
G
S
I
Site 37
S741
K
S
Q
E
G
Q
G
S
I
L
E
T
I
T
L
Site 38
T755
L
I
Q
D
C
K
D
T
L
E
L
I
E
T
E
Site 39
T761
D
T
L
E
L
I
E
T
E
L
T
E
E
E
L
Site 40
T764
E
L
I
E
T
E
L
T
E
E
E
L
D
V
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation