PhosphoNET

           
Protein Info 
   
Short Name:  Bim
Full Name:  Bcl-2-like protein 11
Alias:  Bcl2 interacting mediator of cell death; BCL2 interacting mediator of cell death; Bcl-2 related ovarian death protein; BCL2L11; BCL2-like 11 (apoptosis facilitator); BCL2-like protein 11; Bcl2-like protein 11; BIM; BimEL; BimL; BOD
Type:  Apoptosis protein
Mass (Da):  22171
Number AA:  198
UniProt ID:  O43521
International Prot ID:  IPI00012853
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0019898  GO:0005741 Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:  GO:0008633  GO:0008624   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MAKQPSDVSSECD
Site 2S10KQPSDVSSECDREGR
Site 3S35LRPGAPTSLQTEPQG
Site 4S54NHGGEGDSCPHGSPQ
Site 5S59GDSCPHGSPQGPLAP
Site 6S69GPLAPPASPGPFATR
Site 7S77PGPFATRSPLFIFMR
Site 8S86LFIFMRRSSLLSRSS
Site 9S87FIFMRRSSLLSRSSS
Site 10S90MRRSSLLSRSSSGYF
Site 11S92RSSLLSRSSSGYFSF
Site 12S93SSLLSRSSSGYFSFD
Site 13S94SLLSRSSSGYFSFDT
Site 14Y96LSRSSSGYFSFDTDR
Site 15S98RSSSGYFSFDTDRSP
Site 16T101SGYFSFDTDRSPAPM
Site 17S104FSFDTDRSPAPMSCD
Site 18S109DRSPAPMSCDKSTQT
Site 19S113APMSCDKSTQTPSPP
Site 20T114PMSCDKSTQTPSPPC
Site 21T116SCDKSTQTPSPPCQA
Site 22S118DKSTQTPSPPCQAFN
Site 23S133HYLSAMASMRQAEPA
Site 24Y162IGDEFNAYYARRVFL
Site 25Y163GDEFNAYYARRVFLN
Site 26Y172RRVFLNNYQAAEDHP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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