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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
XRCC3
Full Name:
DNA repair protein XRCC3
Alias:
DNA repair protein XRCC3; RAD51-like; X-ray repair complementing defective repair in Chinese hamster cells 3
Type:
Mass (Da):
37850
Number AA:
346
UniProt ID:
O43542
International Prot ID:
IPI00023073
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003677
GO:0008094
PhosphoSite+
KinaseNET
Biological Process:
GO:0006310
GO:0006281
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
I
K
K
A
K
L
K
S
V
K
E
V
L
H
F
Site 2
S31
V
K
E
V
L
H
F
S
G
P
D
L
K
R
L
Site 3
T39
G
P
D
L
K
R
L
T
N
L
S
S
P
E
V
Site 4
S42
L
K
R
L
T
N
L
S
S
P
E
V
W
H
L
Site 5
S43
K
R
L
T
N
L
S
S
P
E
V
W
H
L
L
Site 6
S54
W
H
L
L
R
T
A
S
L
H
L
R
G
S
S
Site 7
T64
L
R
G
S
S
I
L
T
A
L
Q
L
H
Q
Q
Site 8
T77
Q
Q
K
E
R
F
P
T
Q
H
Q
R
L
S
L
Site 9
S83
P
T
Q
H
Q
R
L
S
L
G
C
P
V
L
D
Site 10
T103
G
L
P
L
D
G
I
T
E
L
A
G
R
S
S
Site 11
S110
T
E
L
A
G
R
S
S
A
G
K
T
Q
L
A
Site 12
T114
G
R
S
S
A
G
K
T
Q
L
A
L
Q
L
C
Site 13
T163
A
Q
Q
P
R
L
R
T
D
V
P
G
E
L
L
Site 14
S177
L
Q
K
L
R
F
G
S
Q
I
F
I
E
H
V
Site 15
T189
E
H
V
A
D
V
D
T
L
L
E
C
V
N
K
Site 16
S225
P
F
R
C
E
F
D
S
Q
A
S
A
P
R
A
Site 17
S237
P
R
A
R
H
L
Q
S
L
G
A
T
L
R
E
Site 18
T241
H
L
Q
S
L
G
A
T
L
R
E
L
S
S
A
Site 19
S246
G
A
T
L
R
E
L
S
S
A
F
Q
S
P
V
Site 20
S281
G
F
W
D
E
R
V
S
P
A
L
G
I
T
W
Site 21
S319
A
R
T
L
R
V
L
S
A
P
H
L
P
P
S
Site 22
S326
S
A
P
H
L
P
P
S
S
C
S
Y
T
I
S
Site 23
S327
A
P
H
L
P
P
S
S
C
S
Y
T
I
S
A
Site 24
S329
H
L
P
P
S
S
C
S
Y
T
I
S
A
E
G
Site 25
T331
P
P
S
S
C
S
Y
T
I
S
A
E
G
V
R
Site 26
S333
S
S
C
S
Y
T
I
S
A
E
G
V
R
G
T
Site 27
T340
S
A
E
G
V
R
G
T
P
G
T
Q
S
H
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation