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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSTPIP1
Full Name:
Proline-serine-threonine phosphatase-interacting protein 1
Alias:
CD2 antigen-binding protein 1; CD2 cytoplasmic tail-binding protein; CD2-binding protein 1; CD2BP1; CD2BP1L; CD2BP1S; H-PIP; PAPAS; PEST phosphatase interacting protein; PEST phosphatase-interacting protein 1; PPIP1; Proline-serine-threonine phosphatase interacting protein 1; PSTPIP
Type:
Adapter/scaffold protein
Mass (Da):
47591
Number AA:
416
UniProt ID:
O43586
International Prot ID:
IPI00022606
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030027
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S72
G
G
Q
T
E
I
N
S
L
R
A
S
F
D
S
Site 2
S76
E
I
N
S
L
R
A
S
F
D
S
L
K
Q
Q
Site 3
S79
S
L
R
A
S
F
D
S
L
K
Q
Q
M
E
N
Site 4
S89
Q
Q
M
E
N
V
G
S
S
H
I
Q
L
A
L
Site 5
T97
S
H
I
Q
L
A
L
T
L
R
E
E
L
R
S
Site 6
S104
T
L
R
E
E
L
R
S
L
E
E
F
R
E
R
Site 7
Y119
Q
K
E
Q
R
K
K
Y
E
A
V
M
D
R
V
Site 8
S129
V
M
D
R
V
Q
K
S
K
L
S
L
Y
K
K
Site 9
S132
R
V
Q
K
S
K
L
S
L
Y
K
K
A
M
E
Site 10
Y134
Q
K
S
K
L
S
L
Y
K
K
A
M
E
S
K
Site 11
S140
L
Y
K
K
A
M
E
S
K
K
T
Y
E
Q
K
Site 12
T143
K
A
M
E
S
K
K
T
Y
E
Q
K
C
R
D
Site 13
Y144
A
M
E
S
K
K
T
Y
E
Q
K
C
R
D
A
Site 14
S162
E
Q
A
F
E
R
I
S
A
N
G
H
Q
K
Q
Site 15
S173
H
Q
K
Q
V
E
K
S
Q
N
K
A
R
Q
C
Site 16
S183
K
A
R
Q
C
K
D
S
A
T
E
A
E
R
V
Site 17
T185
R
Q
C
K
D
S
A
T
E
A
E
R
V
Y
R
Site 18
Y191
A
T
E
A
E
R
V
Y
R
Q
S
I
A
Q
L
Site 19
S194
A
E
R
V
Y
R
Q
S
I
A
Q
L
E
K
V
Site 20
T225
L
Q
E
F
D
R
L
T
I
L
R
N
A
L
W
Site 21
Y249
C
V
K
D
D
E
L
Y
E
E
V
R
L
T
L
Site 22
T255
L
Y
E
E
V
R
L
T
L
E
G
C
S
I
D
Site 23
S267
S
I
D
A
D
I
D
S
F
I
Q
A
K
S
T
Site 24
S273
D
S
F
I
Q
A
K
S
T
G
T
E
P
P
A
Site 25
Y287
A
P
V
P
Y
Q
N
Y
Y
D
R
E
V
T
P
Site 26
Y288
P
V
P
Y
Q
N
Y
Y
D
R
E
V
T
P
L
Site 27
T293
N
Y
Y
D
R
E
V
T
P
L
T
S
S
P
G
Site 28
T296
D
R
E
V
T
P
L
T
S
S
P
G
I
Q
P
Site 29
S298
E
V
T
P
L
T
S
S
P
G
I
Q
P
S
C
Site 30
S304
S
S
P
G
I
Q
P
S
C
G
M
I
K
R
F
Site 31
S318
F
S
G
L
L
H
G
S
P
K
T
T
S
L
A
Site 32
T322
L
H
G
S
P
K
T
T
S
L
A
A
S
A
A
Site 33
S323
H
G
S
P
K
T
T
S
L
A
A
S
A
A
S
Site 34
S327
K
T
T
S
L
A
A
S
A
A
S
T
E
T
L
Site 35
T333
A
S
A
A
S
T
E
T
L
T
P
T
P
E
R
Site 36
T335
A
A
S
T
E
T
L
T
P
T
P
E
R
N
E
Site 37
T337
S
T
E
T
L
T
P
T
P
E
R
N
E
G
V
Site 38
Y345
P
E
R
N
E
G
V
Y
T
A
I
A
V
Q
E
Site 39
T346
E
R
N
E
G
V
Y
T
A
I
A
V
Q
E
I
Site 40
S359
E
I
Q
G
N
P
A
S
P
A
Q
E
Y
R
A
Site 41
Y368
A
Q
E
Y
R
A
L
Y
D
Y
T
A
Q
N
P
Site 42
Y370
E
Y
R
A
L
Y
D
Y
T
A
Q
N
P
D
E
Site 43
S381
N
P
D
E
L
D
L
S
A
G
D
I
L
E
V
Site 44
S411
Q
R
G
F
V
P
G
S
Y
L
E
K
L
_
_
Site 45
Y412
R
G
F
V
P
G
S
Y
L
E
K
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation