KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
XPOT
Full Name:
Exportin-T
Alias:
tRNA exportin
Type:
Mass (Da):
109946
Number AA:
962
UniProt ID:
O43592
International Prot ID:
IPI00306290
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0000049
GO:0003676
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0051234
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
G
L
N
P
N
A
D
S
D
F
R
Q
R
A
L
Site 2
Y24
F
R
Q
R
A
L
A
Y
F
E
Q
L
K
I
S
Site 3
Y47
E
A
L
A
Q
R
T
Y
S
D
D
H
V
K
F
Site 4
S48
A
L
A
Q
R
T
Y
S
D
D
H
V
K
F
F
Site 5
Y66
V
L
E
H
Q
V
K
Y
K
Y
S
E
L
T
T
Site 6
Y68
E
H
Q
V
K
Y
K
Y
S
E
L
T
T
V
Q
Site 7
T73
Y
K
Y
S
E
L
T
T
V
Q
Q
Q
L
I
R
Site 8
T82
Q
Q
Q
L
I
R
E
T
L
I
S
W
L
Q
A
Site 9
T99
L
N
P
Q
P
E
K
T
F
I
R
N
K
A
A
Site 10
T169
S
E
E
A
R
R
N
T
L
I
K
D
T
M
R
Site 11
T174
R
N
T
L
I
K
D
T
M
R
E
Q
C
I
P
Site 12
Y188
P
N
L
V
E
S
W
Y
Q
I
L
Q
N
Y
Q
Site 13
S235
N
M
L
L
G
H
M
S
I
E
V
L
R
E
E
Site 14
S266
D
K
M
K
L
V
E
S
L
C
Q
V
L
Q
S
Site 15
S307
Q
S
L
I
V
S
W
S
K
L
I
K
N
G
D
Site 16
T327
E
A
L
Q
A
I
E
T
K
V
A
L
M
L
Q
Site 17
T362
L
H
I
L
K
Q
L
T
V
L
S
D
Q
Q
K
Site 18
S365
L
K
Q
L
T
V
L
S
D
Q
Q
K
A
N
V
Site 19
Y389
K
L
T
Y
D
E
E
Y
N
F
E
N
E
G
E
Site 20
S432
A
S
V
R
R
V
F
S
S
T
L
Q
N
W
Q
Site 21
S433
S
V
R
R
V
F
S
S
T
L
Q
N
W
Q
T
Site 22
T434
V
R
R
V
F
S
S
T
L
Q
N
W
Q
T
T
Site 23
S469
V
S
H
G
A
H
F
S
G
D
V
S
K
A
S
Site 24
S473
A
H
F
S
G
D
V
S
K
A
S
A
L
Q
D
Site 25
T487
D
M
M
R
T
L
V
T
S
G
V
S
S
Y
Q
Site 26
S488
M
M
R
T
L
V
T
S
G
V
S
S
Y
Q
H
Site 27
S492
L
V
T
S
G
V
S
S
Y
Q
H
T
S
V
T
Site 28
T496
G
V
S
S
Y
Q
H
T
S
V
T
L
E
F
F
Site 29
T499
S
Y
Q
H
T
S
V
T
L
E
F
F
E
T
V
Site 30
T514
V
R
Y
E
K
F
F
T
V
E
P
Q
H
I
P
Site 31
S536
D
H
R
G
L
R
H
S
S
A
K
V
R
S
R
Site 32
S537
H
R
G
L
R
H
S
S
A
K
V
R
S
R
T
Site 33
T544
S
A
K
V
R
S
R
T
A
Y
L
F
S
R
F
Site 34
Y546
K
V
R
S
R
T
A
Y
L
F
S
R
F
V
K
Site 35
S554
L
F
S
R
F
V
K
S
L
N
K
Q
M
N
P
Site 36
S577
I
Q
D
L
L
E
L
S
P
P
E
N
G
H
Q
Site 37
S585
P
P
E
N
G
H
Q
S
L
L
S
S
D
D
Q
Site 38
S588
N
G
H
Q
S
L
L
S
S
D
D
Q
L
F
I
Site 39
S589
G
H
Q
S
L
L
S
S
D
D
Q
L
F
I
Y
Site 40
S606
A
G
V
L
I
V
N
S
E
Y
P
A
E
R
K
Site 41
Y608
V
L
I
V
N
S
E
Y
P
A
E
R
K
Q
A
Site 42
S646
Q
D
E
E
R
Q
A
S
L
A
D
C
L
N
H
Site 43
S659
N
H
A
V
G
F
A
S
R
T
S
K
A
F
S
Site 44
S662
V
G
F
A
S
R
T
S
K
A
F
S
N
K
Q
Site 45
S666
S
R
T
S
K
A
F
S
N
K
Q
T
V
K
Q
Site 46
T670
K
A
F
S
N
K
Q
T
V
K
Q
C
G
C
S
Site 47
S702
L
Q
K
D
I
L
R
S
G
V
R
T
F
L
H
Site 48
S786
P
A
E
E
N
D
Q
S
A
A
L
E
K
Q
M
Site 49
S797
E
K
Q
M
L
R
R
S
Y
F
A
F
L
Q
T
Site 50
Y798
K
Q
M
L
R
R
S
Y
F
A
F
L
Q
T
V
Site 51
Y836
V
I
Q
G
A
V
E
Y
P
D
P
I
A
Q
K
Site 52
Y918
R
G
P
E
C
V
Q
Y
L
Q
Q
E
Y
L
P
Site 53
S926
L
Q
Q
E
Y
L
P
S
L
Q
V
A
P
E
I
Site 54
Y952
D
A
K
V
F
K
N
Y
L
K
V
F
F
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation