PhosphoNET

           
Protein Info 
   
Short Name:  Spry3
Full Name:  Protein sprouty homolog 3
Alias:  antagonist of FGF signaling; HSPRY3; sprouty 3; Sprouty homolog 3; Spry-3; SPRY3X; SPRY3Y; SPY3
Type:  Adapter/scaffold protein
Mass (Da):  31222
Number AA:  288
UniProt ID:  O43610
International Prot ID:  IPI00013371
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0019898   Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0007275  GO:0009966   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S20LPIEQLRSTHASNDY
Site 2T21PIEQLRSTHASNDYV
Site 3S24QLRSTHASNDYVERP
Site 4Y27STHASNDYVERPPAP
Site 5S43KQALSSPSLIVQTHK
Site 6S51LIVQTHKSDWSLATM
Site 7S54QTHKSDWSLATMPTS
Site 8T57KSDWSLATMPTSLPR
Site 9T60WSLATMPTSLPRSLS
Site 10S61SLATMPTSLPRSLSQ
Site 11S65MPTSLPRSLSQCHQL
Site 12S67TSLPRSLSQCHQLQP
Site 13S80QPLPQHLSQSSIASS
Site 14S82LPQHLSQSSIASSMS
Site 15S83PQHLSQSSIASSMSH
Site 16S86LSQSSIASSMSHSTT
Site 17S87SQSSIASSMSHSTTA
Site 18S89SSIASSMSHSTTASD
Site 19S91IASSMSHSTTASDQR
Site 20T92ASSMSHSTTASDQRL
Site 21T93SSMSHSTTASDQRLL
Site 22S95MSHSTTASDQRLLAS
Site 23S102SDQRLLASITPSPSG
Site 24T104QRLLASITPSPSGQS
Site 25S108ASITPSPSGQSIIRT
Site 26S111TPSPSGQSIIRTQPG
Site 27T115SGQSIIRTQPGAGVH
Site 28S136LKGEAEQSAGHPSEH
Site 29T159RCKCVPCTAARPLPS
Site 30Y196CCVKGLFYHCSTDDE
Site 31Y252LHLCQQGYDSLRRPG
Site 32S254LCQQGYDSLRRPGCR
Site 33T268RCKRHTNTVCRKISS
Site 34S274NTVCRKISSGSAPFP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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