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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LDB2
Full Name:
LIM domain-binding protein 2
Alias:
Carboxyl-terminal LIM domain-binding 1; CLIM1; CLIM-1; LDB1
Type:
Transcription, coactivator/corepressor
Mass (Da):
42793
Number AA:
373
UniProt ID:
O43679
International Prot ID:
IPI00014634
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0030274
GO:0003712
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
S
T
P
H
D
P
F
Y
S
S
P
F
G
P
F
Site 2
S11
T
P
H
D
P
F
Y
S
S
P
F
G
P
F
Y
Site 3
S12
P
H
D
P
F
Y
S
S
P
F
G
P
F
Y
R
Site 4
Y18
S
S
P
F
G
P
F
Y
R
R
H
T
P
Y
M
Site 5
T22
G
P
F
Y
R
R
H
T
P
Y
M
V
Q
P
E
Site 6
Y24
F
Y
R
R
H
T
P
Y
M
V
Q
P
E
Y
R
Site 7
Y30
P
Y
M
V
Q
P
E
Y
R
I
Y
E
M
N
K
Site 8
Y33
V
Q
P
E
Y
R
I
Y
E
M
N
K
R
L
Q
Site 9
S41
E
M
N
K
R
L
Q
S
R
T
E
D
S
D
N
Site 10
T43
N
K
R
L
Q
S
R
T
E
D
S
D
N
L
W
Site 11
S46
L
Q
S
R
T
E
D
S
D
N
L
W
W
D
A
Site 12
S68
D
D
A
T
L
T
L
S
F
C
L
E
D
G
P
Site 13
T79
E
D
G
P
K
R
Y
T
I
G
R
T
L
I
P
Site 14
T83
K
R
Y
T
I
G
R
T
L
I
P
R
Y
F
S
Site 15
Y88
G
R
T
L
I
P
R
Y
F
S
T
V
F
E
G
Site 16
Y101
E
G
G
V
T
D
L
Y
Y
I
L
K
H
S
K
Site 17
Y102
G
G
V
T
D
L
Y
Y
I
L
K
H
S
K
E
Site 18
S110
I
L
K
H
S
K
E
S
Y
H
N
S
S
I
T
Site 19
Y111
L
K
H
S
K
E
S
Y
H
N
S
S
I
T
V
Site 20
S114
S
K
E
S
Y
H
N
S
S
I
T
V
D
C
D
Site 21
Y165
W
H
F
T
I
R
Q
Y
R
E
L
V
P
R
S
Site 22
S172
Y
R
E
L
V
P
R
S
I
L
A
M
H
A
Q
Site 23
S188
P
Q
V
L
D
Q
L
S
K
N
I
T
R
M
G
Site 24
T192
D
Q
L
S
K
N
I
T
R
M
G
L
T
N
F
Site 25
Y203
L
T
N
F
T
L
N
Y
L
R
L
C
V
I
L
Site 26
S218
E
P
M
Q
E
L
M
S
R
H
K
T
Y
N
L
Site 27
T222
E
L
M
S
R
H
K
T
Y
N
L
S
P
R
D
Site 28
S226
R
H
K
T
Y
N
L
S
P
R
D
C
L
K
T
Site 29
T254
A
E
P
T
R
Q
P
T
T
K
R
R
K
R
K
Site 30
T255
E
P
T
R
Q
P
T
T
K
R
R
K
R
K
N
Site 31
S263
K
R
R
K
R
K
N
S
T
S
S
T
S
N
S
Site 32
T264
R
R
K
R
K
N
S
T
S
S
T
S
N
S
S
Site 33
S265
R
K
R
K
N
S
T
S
S
T
S
N
S
S
A
Site 34
S266
K
R
K
N
S
T
S
S
T
S
N
S
S
A
G
Site 35
T267
R
K
N
S
T
S
S
T
S
N
S
S
A
G
N
Site 36
S268
K
N
S
T
S
S
T
S
N
S
S
A
G
N
N
Site 37
S270
S
T
S
S
T
S
N
S
S
A
G
N
N
A
N
Site 38
T285
S
T
G
S
K
K
K
T
T
A
A
N
L
S
L
Site 39
S291
K
T
T
A
A
N
L
S
L
S
S
Q
V
P
D
Site 40
T321
D
E
D
E
R
L
I
T
R
L
E
N
T
Q
Y
Site 41
Y328
T
R
L
E
N
T
Q
Y
D
A
A
N
G
M
D
Site 42
S343
D
E
E
D
F
N
N
S
P
A
L
G
N
N
S
Site 43
S350
S
P
A
L
G
N
N
S
P
W
N
S
K
P
P
Site 44
S354
G
N
N
S
P
W
N
S
K
P
P
A
T
Q
E
Site 45
T359
W
N
S
K
P
P
A
T
Q
E
T
K
S
E
N
Site 46
S364
P
A
T
Q
E
T
K
S
E
N
P
P
P
Q
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation