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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BUB3
Full Name:
Mitotic checkpoint protein BUB3
Alias:
BUB3L; budding uninhibited by benzimidazoles 3
Type:
Cell cycle regulation
Mass (Da):
37155
Number AA:
328
UniProt ID:
O43684
International Prot ID:
IPI00013468
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0000776
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0008283
GO:0007093
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
Q
P
P
E
D
G
I
S
S
V
K
F
S
P
N
Site 2
S19
P
P
E
D
G
I
S
S
V
K
F
S
P
N
T
Site 3
S23
G
I
S
S
V
K
F
S
P
N
T
S
Q
F
L
Site 4
S33
T
S
Q
F
L
L
V
S
S
W
D
T
S
V
R
Site 5
S38
L
V
S
S
W
D
T
S
V
R
L
Y
D
V
P
Site 6
Y42
W
D
T
S
V
R
L
Y
D
V
P
A
N
S
M
Site 7
Y53
A
N
S
M
R
L
K
Y
Q
H
T
G
A
V
L
Site 8
T86
L
K
M
H
D
L
N
T
D
Q
E
N
L
V
G
Site 9
T119
V
T
G
S
W
D
Q
T
V
K
L
W
D
P
R
Site 10
T127
V
K
L
W
D
P
R
T
P
C
N
A
G
T
F
Site 11
T133
R
T
P
C
N
A
G
T
F
S
Q
P
E
K
V
Site 12
S135
P
C
N
A
G
T
F
S
Q
P
E
K
V
Y
T
Site 13
Y141
F
S
Q
P
E
K
V
Y
T
L
S
V
S
G
D
Site 14
T142
S
Q
P
E
K
V
Y
T
L
S
V
S
G
D
R
Site 15
S144
P
E
K
V
Y
T
L
S
V
S
G
D
R
L
I
Site 16
T154
G
D
R
L
I
V
G
T
A
G
R
R
V
L
V
Site 17
Y169
W
D
L
R
N
M
G
Y
V
Q
Q
R
R
E
S
Site 18
S176
Y
V
Q
Q
R
R
E
S
S
L
K
Y
Q
T
R
Site 19
S177
V
Q
Q
R
R
E
S
S
L
K
Y
Q
T
R
C
Site 20
Y180
R
R
E
S
S
L
K
Y
Q
T
R
C
I
R
A
Site 21
Y194
A
F
P
N
K
Q
G
Y
V
L
S
S
I
E
G
Site 22
Y207
E
G
R
V
A
V
E
Y
L
D
P
S
P
E
V
Site 23
S211
A
V
E
Y
L
D
P
S
P
E
V
Q
K
K
K
Site 24
Y219
P
E
V
Q
K
K
K
Y
A
F
K
C
H
R
L
Site 25
Y235
E
N
N
I
E
Q
I
Y
P
V
N
A
I
S
F
Site 26
T248
S
F
H
N
I
H
N
T
F
A
T
G
G
S
D
Site 27
Y275
R
L
C
Q
F
H
R
Y
P
T
S
I
A
S
L
Site 28
S278
Q
F
H
R
Y
P
T
S
I
A
S
L
A
F
S
Site 29
S281
R
Y
P
T
S
I
A
S
L
A
F
S
N
D
G
Site 30
S296
T
T
L
A
I
A
S
S
Y
M
Y
E
M
D
D
Site 31
Y299
A
I
A
S
S
Y
M
Y
E
M
D
D
T
E
H
Site 32
T317
G
I
F
I
R
Q
V
T
D
A
E
T
K
P
K
Site 33
T321
R
Q
V
T
D
A
E
T
K
P
K
S
P
C
T
Site 34
S325
D
A
E
T
K
P
K
S
P
C
T
_
_
_
_
Site 35
T328
T
K
P
K
S
P
C
T
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation