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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GSTZ1
Full Name:
Maleylacetoacetate isomerase
Alias:
Glutathione S-alkyltransferase; Glutathione S-aralkyltransferase; Glutathione S-transferase zeta 1; Glutathione transferase zeta 1; GSTZ1-1; MAAI; MAI; S-(hydroxyalkyl)glutathione lyase
Type:
Xenobiotic Metabolism - drug metabolism - cytochrome P450; Mitochondrial; Oxidoreductase; Isomerase; Amino Acid Metabolism - tyrosine; EC 2.5.1.18; EC 5.2.1.2; Xenobiotic Metabolism - metabolism by cytochrome P450; Transferase; Other Amino Acids Metabolism - glutathione
Mass (Da):
24194
Number AA:
216
UniProt ID:
O43708
International Prot ID:
IPI00013809
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0004602
GO:0004364
GO:0016034
PhosphoSite+
KinaseNET
Biological Process:
GO:0006559
GO:0006572
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
Q
A
G
K
P
I
L
Y
S
Y
F
R
S
S
C
Site 2
S10
A
G
K
P
I
L
Y
S
Y
F
R
S
S
C
S
Site 3
Y11
G
K
P
I
L
Y
S
Y
F
R
S
S
C
S
W
Site 4
S17
S
Y
F
R
S
S
C
S
W
R
V
R
I
A
L
Site 5
S47
K
D
R
G
Q
Q
F
S
K
D
F
Q
A
L
N
Site 6
T61
N
P
M
K
Q
V
P
T
L
K
I
D
G
I
T
Site 7
Y78
Q
S
L
A
I
I
E
Y
L
E
E
T
R
P
T
Site 8
T85
Y
L
E
E
T
R
P
T
P
R
L
L
P
Q
D
Site 9
S98
Q
D
P
K
K
R
A
S
V
R
M
I
S
D
L
Site 10
T129
V
G
E
E
M
Q
L
T
W
A
Q
N
A
I
T
Site 11
T136
T
W
A
Q
N
A
I
T
C
G
F
N
A
L
E
Site 12
Y153
L
Q
S
T
A
G
I
Y
C
V
G
D
E
V
T
Site 13
T181
E
R
F
K
V
D
L
T
P
Y
P
T
I
S
S
Site 14
Y183
F
K
V
D
L
T
P
Y
P
T
I
S
S
I
N
Site 15
T185
V
D
L
T
P
Y
P
T
I
S
S
I
N
K
R
Site 16
S188
T
P
Y
P
T
I
S
S
I
N
K
R
L
L
V
Site 17
T210
H
P
C
R
Q
P
D
T
P
T
E
L
R
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation