PhosphoNET

           
Protein Info 
   
Short Name:  WBSCR22
Full Name:  Uncharacterized methyltransferase WBSCR22
Alias:  Williams-Beuren syndrome chromosomal region 22 protein
Type: 
Mass (Da):  31880
Number AA:  281
UniProt ID:  O43709
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y18GGPPELFYDETEARK
Site 2T21PELFYDETEARKYVR
Site 3Y26DETEARKYVRNSRMI
Site 4S30ARKYVRNSRMIDIQT
Site 5T37SRMIDIQTRMAGRAL
Site 6Y48GRALELLYLPENKPC
Site 7S67IGCGTGLSGSYLSDE
Site 8S69CGTGLSGSYLSDEGH
Site 9Y70GTGLSGSYLSDEGHY
Site 10S72GLSGSYLSDEGHYWV
Site 11Y164SRAVLQLYPENSEQL
Site 12S168LQLYPENSEQLELIT
Site 13T176EQLELITTQATKAGF
Site 14Y191SGGMVVDYPNSAKAK
Site 15S228DEVEPRESVFTNERF
Site 16T231EPRESVFTNERFPLR
Site 17S240ERFPLRMSRRGMVRK
Site 18S248RRGMVRKSRAWVLEK
Site 19T270GREVRPDTQYTGRKR
Site 20Y272EVRPDTQYTGRKRKP
Site 21T273VRPDTQYTGRKRKPR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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