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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AP1G1
Full Name:
AP-1 complex subunit gamma-1
Alias:
Adapter-related protein complex 1 gamma- 1; Adaptor-related protein complex 1, gamma 1 subunit; ADTG; CLAPG1; Clathrin assembly protein complex 1 gamma-1 large chain; Gamma1-adaptin; Gamma-adaptin; Golgi adaptor HA1/AP1 adaptin subunit gamma-1
Type:
Vesicle protein
Mass (Da):
91351
Number AA:
822
UniProt ID:
O43747
International Prot ID:
IPI00643591
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0044431
GO:0030131
GO:0030136
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006897
GO:0006886
GO:0006892
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
R
L
R
E
L
I
R
T
I
R
T
A
R
T
Q
Site 2
S37
E
C
A
A
I
R
S
S
F
R
E
E
D
N
T
Site 3
T44
S
F
R
E
E
D
N
T
Y
R
C
R
N
V
A
Site 4
Y45
F
R
E
E
D
N
T
Y
R
C
R
N
V
A
K
Site 5
Y55
R
N
V
A
K
L
L
Y
M
H
M
L
G
Y
P
Site 6
Y61
L
Y
M
H
M
L
G
Y
P
A
H
F
G
Q
L
Site 7
S76
E
C
L
K
L
I
A
S
Q
K
F
T
D
K
R
Site 8
T80
L
I
A
S
Q
K
F
T
D
K
R
I
G
Y
L
Site 9
T148
E
V
E
K
L
L
K
T
S
N
S
Y
L
R
K
Site 10
S151
K
L
L
K
T
S
N
S
Y
L
R
K
K
A
A
Site 11
S205
L
T
E
M
C
E
R
S
P
D
M
L
A
H
F
Site 12
S229
I
L
K
N
L
I
M
S
G
Y
S
P
E
H
D
Site 13
S232
N
L
I
M
S
G
Y
S
P
E
H
D
V
S
G
Site 14
S238
Y
S
P
E
H
D
V
S
G
I
S
D
P
F
L
Site 15
S241
E
H
D
V
S
G
I
S
D
P
F
L
Q
V
R
Site 16
S263
L
G
R
N
D
D
D
S
S
E
A
M
N
D
I
Site 17
S264
G
R
N
D
D
D
S
S
E
A
M
N
D
I
L
Site 18
Y326
N
N
D
K
N
I
R
Y
V
A
L
T
S
L
L
Site 19
T335
A
L
T
S
L
L
K
T
V
Q
T
D
H
N
A
Site 20
S348
N
A
V
Q
R
H
R
S
T
I
V
D
C
L
K
Site 21
T349
A
V
Q
R
H
R
S
T
I
V
D
C
L
K
D
Site 22
S360
C
L
K
D
L
D
V
S
I
K
R
R
A
M
E
Site 23
S369
K
R
R
A
M
E
L
S
F
A
L
V
N
G
N
Site 24
S391
E
L
L
Y
F
L
D
S
C
E
P
E
F
K
A
Site 25
Y411
I
F
L
A
A
E
K
Y
A
P
S
K
R
W
H
Site 26
T421
S
K
R
W
H
I
D
T
I
M
R
V
L
T
T
Site 27
S431
R
V
L
T
T
A
G
S
Y
V
R
D
D
A
V
Site 28
Y454
N
S
V
E
M
H
A
Y
T
V
Q
R
L
Y
K
Site 29
Y460
A
Y
T
V
Q
R
L
Y
K
A
I
L
G
D
Y
Site 30
Y467
Y
K
A
I
L
G
D
Y
S
Q
Q
P
L
V
Q
Site 31
S468
K
A
I
L
G
D
Y
S
Q
Q
P
L
V
Q
V
Site 32
T522
S
N
M
S
T
S
V
T
R
G
Y
A
L
T
A
Site 33
T538
M
K
L
S
T
R
F
T
C
T
V
N
R
I
K
Site 34
T540
L
S
T
R
F
T
C
T
V
N
R
I
K
K
V
Site 35
S549
N
R
I
K
K
V
V
S
I
Y
G
S
S
I
D
Site 36
Y573
Y
N
A
L
F
K
K
Y
D
H
M
R
S
A
L
Site 37
S578
K
K
Y
D
H
M
R
S
A
L
L
E
R
M
P
Site 38
T592
P
V
M
E
K
V
T
T
N
G
P
T
E
I
V
Site 39
T601
G
P
T
E
I
V
Q
T
N
G
E
T
E
P
A
Site 40
T612
T
E
P
A
P
L
E
T
K
P
P
P
S
G
P
Site 41
S617
L
E
T
K
P
P
P
S
G
P
Q
P
T
S
Q
Site 42
S623
P
S
G
P
Q
P
T
S
Q
A
N
D
L
L
D
Site 43
T646
P
V
I
P
T
A
P
T
S
K
P
S
S
A
G
Site 44
S647
V
I
P
T
A
P
T
S
K
P
S
S
A
G
G
Site 45
S651
A
P
T
S
K
P
S
S
A
G
G
E
L
L
D
Site 46
S692
P
F
L
L
D
G
L
S
S
Q
P
L
F
N
D
Site 47
Y710
G
I
P
S
I
T
A
Y
S
K
N
G
L
K
I
Site 48
T720
N
G
L
K
I
E
F
T
F
E
R
S
N
T
N
Site 49
T726
F
T
F
E
R
S
N
T
N
P
S
V
T
V
I
Site 50
S729
E
R
S
N
T
N
P
S
V
T
V
I
T
I
Q
Site 51
T746
N
S
T
E
L
D
M
T
D
F
V
F
Q
A
A
Site 52
T799
L
R
M
R
I
K
L
T
Y
N
H
K
G
S
A
Site 53
Y800
R
M
R
I
K
L
T
Y
N
H
K
G
S
A
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation