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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUDT21
Full Name:
Cleavage and polyadenylation specificity factor subunit 5
Alias:
Cleavage and polyadenylation specificity factor 25 kDa subunit; Cleavage and polyadenylation specificity factor 5; CPSF 25 kDa subunit; CPSF25; CPSF5; Nucleoside diphosphate-linked moiety X motif 21; Nudix motif 21
Type:
RNA binding protein
Mass (Da):
26227
Number AA:
227
UniProt ID:
O43809
International Prot ID:
IPI00646917
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005813
GO:0005815
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
GO:0000375
GO:0000377
GO:0000398
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
S
V
V
P
P
N
R
S
Q
T
G
W
P
R
G
Site 2
T11
V
P
P
N
R
S
Q
T
G
W
P
R
G
V
T
Site 3
T18
T
G
W
P
R
G
V
T
Q
F
G
N
K
Y
I
Site 4
Y24
V
T
Q
F
G
N
K
Y
I
Q
Q
T
K
P
L
Site 5
T32
I
Q
Q
T
K
P
L
T
L
E
R
T
I
N
L
Site 6
T36
K
P
L
T
L
E
R
T
I
N
L
Y
P
L
T
Site 7
Y40
L
E
R
T
I
N
L
Y
P
L
T
N
Y
T
F
Site 8
T43
T
I
N
L
Y
P
L
T
N
Y
T
F
G
T
K
Site 9
Y45
N
L
Y
P
L
T
N
Y
T
F
G
T
K
E
P
Site 10
T46
L
Y
P
L
T
N
Y
T
F
G
T
K
E
P
L
Site 11
T49
L
T
N
Y
T
F
G
T
K
E
P
L
Y
E
K
Site 12
Y54
F
G
T
K
E
P
L
Y
E
K
D
S
S
V
A
Site 13
S58
E
P
L
Y
E
K
D
S
S
V
A
A
R
F
Q
Site 14
S59
P
L
Y
E
K
D
S
S
V
A
A
R
F
Q
R
Site 15
T101
V
L
L
L
Q
L
G
T
T
F
F
K
L
P
G
Site 16
T102
L
L
L
Q
L
G
T
T
F
F
K
L
P
G
G
Site 17
T126
E
G
L
K
R
L
M
T
E
I
L
G
R
Q
D
Site 18
Y158
P
N
F
E
P
P
Q
Y
P
Y
I
P
A
H
I
Site 19
Y202
A
A
P
L
F
E
L
Y
D
N
A
P
G
Y
G
Site 20
S220
S
S
L
P
Q
L
L
S
R
F
N
F
I
Y
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation