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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATP9B
Full Name:
Probable phospholipid-transporting ATPase IIB
Alias:
ATPase type IV, phospholipid transporting (P-type); ATPase, class II, type 9B; ATPASEP; ATPIIB; HUSSY-20
Type:
Hydrolase; Transporter; EC 3.6.3.1
Mass (Da):
129300
Number AA:
UniProt ID:
O43861
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0015662
GO:0019829
PhosphoSite+
KinaseNET
Biological Process:
GO:0006754
GO:0015917
GO:0015914
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
A
N
R
K
R
A
A
Y
Y
S
A
A
G
P
R
Site 2
Y26
N
R
K
R
A
A
Y
Y
S
A
A
G
P
R
P
Site 3
S27
R
K
R
A
A
Y
Y
S
A
A
G
P
R
P
G
Site 4
S39
R
P
G
A
D
R
H
S
R
Y
Q
L
E
D
E
Site 5
S58
D
E
M
P
L
M
M
S
E
E
G
F
E
N
E
Site 6
S67
E
G
F
E
N
E
E
S
D
Y
H
T
L
P
R
Site 7
Y69
F
E
N
E
E
S
D
Y
H
T
L
P
R
A
R
Site 8
T71
N
E
E
S
D
Y
H
T
L
P
R
A
R
I
M
Site 9
S134
E
E
K
H
P
R
N
S
I
K
N
Q
K
Y
N
Site 10
Y140
N
S
I
K
N
Q
K
Y
N
V
F
T
F
I
P
Site 11
S213
Q
R
D
K
E
V
N
S
Q
L
Y
S
K
L
T
Site 12
S217
E
V
N
S
Q
L
Y
S
K
L
T
V
R
G
K
Site 13
T220
S
Q
L
Y
S
K
L
T
V
R
G
K
V
Q
V
Site 14
S229
R
G
K
V
Q
V
K
S
S
D
I
Q
V
G
D
Site 15
S230
G
K
V
Q
V
K
S
S
D
I
Q
V
G
D
L
Site 16
S248
E
K
N
Q
R
I
P
S
D
M
V
F
L
R
T
Site 17
S256
D
M
V
F
L
R
T
S
E
K
A
G
S
C
F
Site 18
S261
R
T
S
E
K
A
G
S
C
F
I
R
T
D
Q
Site 19
Y299
D
L
F
S
I
S
A
Y
V
Y
A
Q
K
P
Q
Site 20
Y301
F
S
I
S
A
Y
V
Y
A
Q
K
P
Q
M
D
Site 21
S311
K
P
Q
M
D
I
H
S
F
E
G
T
F
T
R
Site 22
T315
D
I
H
S
F
E
G
T
F
T
R
E
D
S
D
Site 23
T317
H
S
F
E
G
T
F
T
R
E
D
S
D
P
P
Site 24
S321
G
T
F
T
R
E
D
S
D
P
P
I
H
E
S
Site 25
S328
S
D
P
P
I
H
E
S
L
S
I
E
N
T
L
Site 26
S330
P
P
I
H
E
S
L
S
I
E
N
T
L
W
A
Site 27
S359
Y
T
G
K
E
T
R
S
V
M
N
T
S
N
P
Site 28
T363
E
T
R
S
V
M
N
T
S
N
P
K
N
K
V
Site 29
Y406
Q
G
F
V
G
P
W
Y
R
N
L
F
R
F
L
Site 30
T448
K
D
E
N
I
P
G
T
V
V
R
T
S
T
I
Site 31
S453
P
G
T
V
V
R
T
S
T
I
P
E
E
L
G
Site 32
T454
G
T
V
V
R
T
S
T
I
P
E
E
L
G
R
Site 33
Y464
E
E
L
G
R
L
V
Y
L
L
T
D
K
T
G
Site 34
T470
V
Y
L
L
T
D
K
T
G
T
L
T
Q
N
E
Site 35
T487
F
K
R
L
H
L
G
T
V
S
Y
G
A
D
T
Site 36
S489
R
L
H
L
G
T
V
S
Y
G
A
D
T
M
D
Site 37
T494
T
V
S
Y
G
A
D
T
M
D
E
I
Q
S
H
Site 38
S500
D
T
M
D
E
I
Q
S
H
V
R
D
S
Y
S
Site 39
S505
I
Q
S
H
V
R
D
S
Y
S
Q
M
Q
S
Q
Site 40
Y506
Q
S
H
V
R
D
S
Y
S
Q
M
Q
S
Q
A
Site 41
S507
S
H
V
R
D
S
Y
S
Q
M
Q
S
Q
A
G
Site 42
S511
D
S
Y
S
Q
M
Q
S
Q
A
G
G
N
N
T
Site 43
S520
A
G
G
N
N
T
G
S
T
P
L
R
K
A
Q
Site 44
T521
G
G
N
N
T
G
S
T
P
L
R
K
A
Q
S
Site 45
S528
T
P
L
R
K
A
Q
S
S
A
P
K
V
R
K
Site 46
S529
P
L
R
K
A
Q
S
S
A
P
K
V
R
K
S
Site 47
S536
S
A
P
K
V
R
K
S
V
S
S
R
I
H
E
Site 48
S538
P
K
V
R
K
S
V
S
S
R
I
H
E
A
V
Site 49
S539
K
V
R
K
S
V
S
S
R
I
H
E
A
V
K
Site 50
Y558
C
H
N
V
T
P
V
Y
E
S
R
A
G
V
T
Site 51
S578
A
E
A
D
Q
D
F
S
D
E
N
R
T
Y
Q
Site 52
T583
D
F
S
D
E
N
R
T
Y
Q
A
S
S
P
D
Site 53
Y584
F
S
D
E
N
R
T
Y
Q
A
S
S
P
D
E
Site 54
S587
E
N
R
T
Y
Q
A
S
S
P
D
E
V
A
L
Site 55
S588
N
R
T
Y
Q
A
S
S
P
D
E
V
A
L
V
Site 56
T611
T
L
V
S
R
D
L
T
S
M
Q
L
K
T
P
Site 57
S612
L
V
S
R
D
L
T
S
M
Q
L
K
T
P
S
Site 58
T617
L
T
S
M
Q
L
K
T
P
S
G
Q
V
L
S
Site 59
S619
S
M
Q
L
K
T
P
S
G
Q
V
L
S
F
C
Site 60
S635
L
Q
L
F
P
F
T
S
E
S
K
R
M
G
V
Site 61
T653
D
E
S
T
A
E
I
T
F
Y
M
K
G
A
D
Site 62
Y655
S
T
A
E
I
T
F
Y
M
K
G
A
D
V
A
Site 63
S664
K
G
A
D
V
A
M
S
P
I
V
Q
Y
N
D
Site 64
Y700
K
A
L
T
E
E
Q
Y
Q
D
F
E
S
R
Y
Site 65
Y707
Y
Q
D
F
E
S
R
Y
T
Q
A
K
L
S
M
Site 66
T708
Q
D
F
E
S
R
Y
T
Q
A
K
L
S
M
H
Site 67
S713
R
Y
T
Q
A
K
L
S
M
H
D
R
S
L
K
Site 68
T751
L
Q
A
D
V
R
P
T
L
E
M
L
R
N
A
Site 69
S779
T
A
T
C
I
A
K
S
S
H
L
V
S
R
T
Site 70
S780
A
T
C
I
A
K
S
S
H
L
V
S
R
T
Q
Site 71
S784
A
K
S
S
H
L
V
S
R
T
Q
D
I
H
I
Site 72
T786
S
S
H
L
V
S
R
T
Q
D
I
H
I
F
R
Site 73
T796
I
H
I
F
R
Q
V
T
S
R
G
E
A
H
L
Site 74
Y829
S
L
E
V
C
L
K
Y
Y
E
H
E
F
V
E
Site 75
Y830
L
E
V
C
L
K
Y
Y
E
H
E
F
V
E
L
Site 76
T859
T
Q
K
A
R
I
V
T
L
L
Q
Q
H
T
G
Site 77
T865
V
T
L
L
Q
Q
H
T
G
R
R
T
C
A
I
Site 78
T869
Q
Q
H
T
G
R
R
T
C
A
I
G
D
G
G
Site 79
S880
G
D
G
G
N
D
V
S
M
I
Q
A
A
D
C
Site 80
S900
G
K
E
G
K
Q
A
S
L
A
A
D
F
S
I
Site 81
S924
L
M
V
H
G
R
N
S
Y
K
R
S
A
A
L
Site 82
Y925
M
V
H
G
R
N
S
Y
K
R
S
A
A
L
G
Site 83
S928
G
R
N
S
Y
K
R
S
A
A
L
G
Q
F
V
Site 84
Y995
K
P
E
M
A
M
L
Y
P
E
L
Y
K
D
L
Site 85
Y999
A
M
L
Y
P
E
L
Y
K
D
L
T
K
G
R
Site 86
T1003
P
E
L
Y
K
D
L
T
K
G
R
S
L
S
F
Site 87
S1007
K
D
L
T
K
G
R
S
L
S
F
K
T
F
L
Site 88
Y1132
L
P
L
Y
V
L
K
Y
L
R
R
K
L
S
P
Site 89
S1138
K
Y
L
R
R
K
L
S
P
P
S
Y
C
K
L
Site 90
S1141
R
R
K
L
S
P
P
S
Y
C
K
L
A
S
_
Site 91
Y1142
R
K
L
S
P
P
S
Y
C
K
L
A
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation