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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHST1
Full Name:
Carbohydrate sulfotransferase 1
Alias:
C6ST; Carbohydrate (keratan sulfate Gal-6) sulfotransferase 1; EC 2.8.2.21; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1; GST-1; Keratan sulfate Gal-6 sulfotransferase; KS6ST; KSGal6ST; KSST
Type:
Transferase; Glycan Metabolism - keratan sulfate biosynthesis; EC 2.8.2.21
Mass (Da):
46715
Number AA:
411
UniProt ID:
O43916
International Prot ID:
IPI00021119
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000139
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0045130
PhosphoSite+
KinaseNET
Biological Process:
GO:0006012
GO:0006954
GO:0042339
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
I
Q
Y
T
A
I
R
T
F
T
A
K
S
F
H
Site 2
T27
Y
T
A
I
R
T
F
T
A
K
S
F
H
T
C
Site 3
S50
A
E
R
L
C
E
E
S
P
T
F
A
Y
N
L
Site 4
T52
R
L
C
E
E
S
P
T
F
A
Y
N
L
S
R
Site 5
Y55
E
E
S
P
T
F
A
Y
N
L
S
R
K
T
H
Site 6
S58
P
T
F
A
Y
N
L
S
R
K
T
H
I
L
I
Site 7
S74
A
T
T
R
S
G
S
S
F
V
G
Q
L
F
N
Site 8
Y88
N
Q
H
L
D
V
F
Y
L
F
E
P
L
Y
H
Site 9
T105
N
T
L
I
P
R
F
T
Q
G
K
S
P
A
D
Site 10
S109
P
R
F
T
Q
G
K
S
P
A
D
R
R
V
M
Site 11
S126
A
S
R
D
L
L
R
S
L
Y
D
C
D
L
Y
Site 12
Y133
S
L
Y
D
C
D
L
Y
F
L
E
N
Y
I
K
Site 13
Y138
D
L
Y
F
L
E
N
Y
I
K
P
P
P
V
N
Site 14
T148
P
P
P
V
N
H
T
T
D
R
I
F
R
R
G
Site 15
S157
R
I
F
R
R
G
A
S
R
V
L
C
S
R
P
Site 16
S201
A
E
A
C
R
E
R
S
H
V
A
I
K
T
V
Site 17
T207
R
S
H
V
A
I
K
T
V
R
V
P
E
V
N
Site 18
S242
D
P
R
G
I
L
A
S
R
S
E
T
F
R
D
Site 19
S244
R
G
I
L
A
S
R
S
E
T
F
R
D
T
Y
Site 20
T246
I
L
A
S
R
S
E
T
F
R
D
T
Y
R
L
Site 21
Y251
S
E
T
F
R
D
T
Y
R
L
W
R
L
W
Y
Site 22
Y258
Y
R
L
W
R
L
W
Y
G
T
G
R
K
P
Y
Site 23
T260
L
W
R
L
W
Y
G
T
G
R
K
P
Y
N
L
Site 24
Y265
Y
G
T
G
R
K
P
Y
N
L
D
V
T
Q
L
Site 25
T270
K
P
Y
N
L
D
V
T
Q
L
T
T
V
C
E
Site 26
T274
L
D
V
T
Q
L
T
T
V
C
E
D
F
S
N
Site 27
S280
T
T
V
C
E
D
F
S
N
S
V
S
T
G
L
Site 28
S282
V
C
E
D
F
S
N
S
V
S
T
G
L
M
R
Site 29
S284
E
D
F
S
N
S
V
S
T
G
L
M
R
P
P
Site 30
Y297
P
P
W
L
K
G
K
Y
M
L
V
R
Y
E
D
Site 31
Y302
G
K
Y
M
L
V
R
Y
E
D
L
A
R
N
P
Site 32
T341
N
N
T
R
G
D
P
T
L
G
K
H
K
Y
G
Site 33
Y347
P
T
L
G
K
H
K
Y
G
T
V
R
N
S
A
Site 34
T349
L
G
K
H
K
Y
G
T
V
R
N
S
A
A
T
Site 35
S353
K
Y
G
T
V
R
N
S
A
A
T
A
E
K
W
Site 36
S365
E
K
W
R
F
R
L
S
Y
D
I
V
A
F
A
Site 37
Y366
K
W
R
F
R
L
S
Y
D
I
V
A
F
A
Q
Site 38
S390
L
G
Y
K
I
A
A
S
E
E
E
L
K
N
P
Site 39
S398
E
E
E
L
K
N
P
S
V
S
L
V
E
E
R
Site 40
S400
E
L
K
N
P
S
V
S
L
V
E
E
R
D
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation