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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RAD21
Full Name:
Double-strand-break repair protein rad21 homolog
Alias:
HHR21; HR21; KIAA0078; Nuclear matrix protein 1; NXP1; NXP-1; SCC1; SCC1 homolog
Type:
Mass (Da):
71690
Number AA:
631
UniProt ID:
O60216
International Prot ID:
IPI00006715
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000228
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0051301
GO:0007059
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S40
F
E
C
N
L
E
S
S
V
E
S
I
I
S
P
Site 2
S43
N
L
E
S
S
V
E
S
I
I
S
P
K
V
K
Site 3
S46
S
S
V
E
S
I
I
S
P
K
V
K
M
A
L
Site 4
T55
K
V
K
M
A
L
R
T
S
G
H
L
L
L
G
Site 5
S56
V
K
M
A
L
R
T
S
G
H
L
L
L
G
V
Site 6
Y67
L
L
G
V
V
R
I
Y
H
R
K
A
K
Y
L
Site 7
Y73
I
Y
H
R
K
A
K
Y
L
L
A
D
C
N
E
Site 8
T109
E
A
A
Y
N
A
I
T
L
P
E
E
F
H
D
Site 9
S134
I
D
V
A
Q
Q
F
S
L
N
Q
S
R
V
E
Site 10
S138
Q
Q
F
S
L
N
Q
S
R
V
E
E
I
T
M
Site 11
T144
Q
S
R
V
E
E
I
T
M
R
E
E
V
G
N
Site 12
S153
R
E
E
V
G
N
I
S
I
L
Q
E
N
D
F
Site 13
S175
R
E
I
M
R
E
G
S
A
F
E
D
D
D
M
Site 14
S185
E
D
D
D
M
L
V
S
T
T
T
S
N
L
L
Site 15
S195
T
S
N
L
L
L
E
S
E
Q
S
T
S
N
L
Site 16
S198
L
L
L
E
S
E
Q
S
T
S
N
L
N
E
K
Site 17
S200
L
E
S
E
Q
S
T
S
N
L
N
E
K
I
N
Site 18
Y211
E
K
I
N
H
L
E
Y
E
D
Q
Y
K
D
D
Site 19
Y215
H
L
E
Y
E
D
Q
Y
K
D
D
N
F
G
E
Site 20
S235
I
L
D
D
K
L
I
S
N
N
D
G
G
I
F
Site 21
S277
V
S
M
G
G
P
D
S
P
D
S
V
D
P
V
Site 22
S280
G
G
P
D
S
P
D
S
V
D
P
V
E
P
M
Site 23
T289
D
P
V
E
P
M
P
T
M
T
D
Q
T
T
L
Site 24
T295
P
T
M
T
D
Q
T
T
L
V
P
N
E
E
E
Site 25
T312
A
L
E
P
I
D
I
T
V
K
E
T
K
A
K
Site 26
S328
K
R
K
L
I
V
D
S
V
K
E
L
D
S
K
Site 27
T336
V
K
E
L
D
S
K
T
I
R
A
Q
L
S
D
Site 28
S342
K
T
I
R
A
Q
L
S
D
Y
S
D
I
V
T
Site 29
S345
R
A
Q
L
S
D
Y
S
D
I
V
T
T
L
D
Site 30
T349
S
D
Y
S
D
I
V
T
T
L
D
L
A
P
P
Site 31
T350
D
Y
S
D
I
V
T
T
L
D
L
A
P
P
T
Site 32
T366
K
L
M
M
W
K
E
T
G
G
V
E
K
L
F
Site 33
S374
G
G
V
E
K
L
F
S
L
P
A
Q
P
L
W
Site 34
T394
K
L
F
T
R
C
L
T
P
L
V
P
E
D
L
Site 35
S454
E
P
S
R
L
Q
E
S
V
M
E
A
S
R
T
Site 36
S459
Q
E
S
V
M
E
A
S
R
T
N
I
D
E
S
Site 37
T461
S
V
M
E
A
S
R
T
N
I
D
E
S
A
M
Site 38
S466
S
R
T
N
I
D
E
S
A
M
P
P
P
P
P
Site 39
S545
E
E
E
D
E
D
A
S
G
G
D
Q
D
Q
E
Site 40
S580
K
T
G
A
E
S
I
S
L
L
E
L
C
R
N
Site 41
T588
L
L
E
L
C
R
N
T
N
R
K
Q
A
A
A
Site 42
S618
L
T
Q
E
E
P
Y
S
D
I
I
A
T
P
G
Site 43
T623
P
Y
S
D
I
I
A
T
P
G
P
R
F
H
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation