PhosphoNET

           
Protein Info 
   
Short Name:  KLK8
Full Name:  Kallikrein-8
Alias:  Neuropsin;Ovasin;Serine protease 19;Serine protease TADG-14;Tumor-associated differentially expressed gene 14 protein
Type: 
Mass (Da):  28048
Number AA:  260
UniProt ID:  O60259
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T70VGGNWVLTAAHCKKP
Site 2Y79AHCKKPKYTVRLGDH
Site 3T80HCKKPKYTVRLGDHS
Site 4S87TVRLGDHSLQNKDGP
Site 5Y109QSIPHPCYNSSDVED
Site 6S131LQLRDQASLGSKVKP
Site 7S140GSKVKPISLADHCTQ
Site 8T146ISLADHCTQPGQKCT
Site 9T153TQPGQKCTVSGWGTV
Site 10S155PGQKCTVSGWGTVTS
Site 11T159CTVSGWGTVTSPREN
Site 12S162SGWGTVTSPRENFPD
Site 13T170PRENFPDTLNCAEVK
Site 14Y188QKKCEDAYPGQITDG
Site 15S201DGMVCAGSSKGADTC
Site 16T207GSSKGADTCQGDSGG
Site 17T226DGALQGITSWGSDPC
Site 18S227GALQGITSWGSDPCG
Site 19S230QGITSWGSDPCGRSD
Site 20S236GSDPCGRSDKPGVYT
Site 21Y242RSDKPGVYTNICRYL
Site 22Y248VYTNICRYLDWIKKI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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