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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRAK2
Full Name:
Trafficking kinesin-binding protein 2
Alias:
ALS2CR3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein; CALS-C; GRIF1; GRIF-1; KIAA0549; OIP98; Trafficking kinesin-binding 2; Trafficking protein, kinesin binding 2
Type:
Unknown function
Mass (Da):
101419
Number AA:
914
UniProt ID:
O60296
International Prot ID:
IPI00297257
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0050811
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Trafficking kinesin-binding protein 2 pan-specific antibody AB-NN348-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN348-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
S
Q
N
A
I
F
T
S
P
T
G
E
E
N
L
Site 2
S21
G
E
E
N
L
M
N
S
N
H
R
D
S
E
S
Site 3
S26
M
N
S
N
H
R
D
S
E
S
I
T
D
V
C
Site 4
S28
S
N
H
R
D
S
E
S
I
T
D
V
C
S
N
Site 5
T30
H
R
D
S
E
S
I
T
D
V
C
S
N
E
D
Site 6
S34
E
S
I
T
D
V
C
S
N
E
D
L
P
E
V
Site 7
Y54
L
E
E
Q
L
P
Q
Y
R
L
K
V
D
T
L
Site 8
T60
Q
Y
R
L
K
V
D
T
L
F
L
Y
E
N
Q
Site 9
Y64
K
V
D
T
L
F
L
Y
E
N
Q
D
W
T
Q
Site 10
S80
P
H
Q
R
Q
H
A
S
D
A
L
S
P
V
L
Site 11
S84
Q
H
A
S
D
A
L
S
P
V
L
A
E
E
T
Site 12
Y94
L
A
E
E
T
F
R
Y
M
I
L
G
T
D
R
Site 13
T99
F
R
Y
M
I
L
G
T
D
R
V
E
Q
M
T
Site 14
T106
T
D
R
V
E
Q
M
T
K
T
Y
N
D
I
D
Site 15
T108
R
V
E
Q
M
T
K
T
Y
N
D
I
D
M
V
Site 16
S144
L
K
R
N
H
V
L
S
E
Q
N
E
S
L
E
Site 17
S149
V
L
S
E
Q
N
E
S
L
E
E
Q
L
G
Q
Site 18
S179
D
E
L
L
R
I
V
S
I
A
S
E
E
S
E
Site 19
S185
V
S
I
A
S
E
E
S
E
T
D
S
S
C
S
Site 20
T187
I
A
S
E
E
S
E
T
D
S
S
C
S
T
P
Site 21
S189
S
E
E
S
E
T
D
S
S
C
S
T
P
L
R
Site 22
S190
E
E
S
E
T
D
S
S
C
S
T
P
L
R
F
Site 23
T193
E
T
D
S
S
C
S
T
P
L
R
F
N
E
S
Site 24
S200
T
P
L
R
F
N
E
S
F
S
L
S
Q
G
L
Site 25
S202
L
R
F
N
E
S
F
S
L
S
Q
G
L
L
Q
Site 26
S204
F
N
E
S
F
S
L
S
Q
G
L
L
Q
L
E
Site 27
T236
S
K
A
C
H
I
K
T
E
T
V
T
Y
E
E
Site 28
T238
A
C
H
I
K
T
E
T
V
T
Y
E
E
K
E
Site 29
Y241
I
K
T
E
T
V
T
Y
E
E
K
E
Q
Q
L
Site 30
S250
E
K
E
Q
Q
L
V
S
D
C
V
K
E
L
R
Site 31
T259
C
V
K
E
L
R
E
T
N
A
Q
M
S
R
M
Site 32
T267
N
A
Q
M
S
R
M
T
E
E
L
S
G
K
S
Site 33
S271
S
R
M
T
E
E
L
S
G
K
S
D
E
L
I
Site 34
Y280
K
S
D
E
L
I
R
Y
Q
E
E
L
S
S
L
Site 35
S285
I
R
Y
Q
E
E
L
S
S
L
L
S
Q
I
V
Site 36
S286
R
Y
Q
E
E
L
S
S
L
L
S
Q
I
V
D
Site 37
S289
E
E
L
S
S
L
L
S
Q
I
V
D
L
Q
H
Site 38
T323
K
D
A
Q
R
Q
L
T
M
E
L
H
E
L
Q
Site 39
S343
C
L
G
M
L
H
E
S
Q
E
E
I
K
E
L
Site 40
S352
E
E
I
K
E
L
R
S
R
S
G
P
T
A
H
Site 41
S354
I
K
E
L
R
S
R
S
G
P
T
A
H
L
Y
Site 42
Y361
S
G
P
T
A
H
L
Y
F
S
Q
S
Y
G
A
Site 43
S363
P
T
A
H
L
Y
F
S
Q
S
Y
G
A
F
T
Site 44
S365
A
H
L
Y
F
S
Q
S
Y
G
A
F
T
G
E
Site 45
T381
L
A
A
E
I
E
G
T
M
R
K
K
L
S
L
Site 46
S387
G
T
M
R
K
K
L
S
L
D
E
E
S
S
L
Site 47
S393
L
S
L
D
E
E
S
S
L
F
K
Q
K
A
Q
Site 48
T407
Q
Q
K
R
V
F
D
T
V
R
I
A
N
D
T
Site 49
T414
T
V
R
I
A
N
D
T
R
G
R
S
I
S
F
Site 50
S418
A
N
D
T
R
G
R
S
I
S
F
P
A
L
L
Site 51
S420
D
T
R
G
R
S
I
S
F
P
A
L
L
P
I
Site 52
S433
P
I
P
G
S
N
R
S
S
V
I
M
T
A
K
Site 53
S434
I
P
G
S
N
R
S
S
V
I
M
T
A
K
P
Site 54
T438
N
R
S
S
V
I
M
T
A
K
P
F
E
S
G
Site 55
S453
L
Q
Q
T
E
D
K
S
L
L
N
Q
G
S
S
Site 56
S459
K
S
L
L
N
Q
G
S
S
S
E
E
V
A
G
Site 57
S460
S
L
L
N
Q
G
S
S
S
E
E
V
A
G
S
Site 58
S461
L
L
N
Q
G
S
S
S
E
E
V
A
G
S
S
Site 59
S467
S
S
E
E
V
A
G
S
S
Q
K
M
G
Q
P
Site 60
S468
S
E
E
V
A
G
S
S
Q
K
M
G
Q
P
G
Site 61
T484
S
G
D
S
D
L
A
T
A
L
H
R
L
S
L
Site 62
S490
A
T
A
L
H
R
L
S
L
R
R
Q
N
Y
L
Site 63
Y496
L
S
L
R
R
Q
N
Y
L
S
E
K
Q
F
F
Site 64
S498
L
R
R
Q
N
Y
L
S
E
K
Q
F
F
A
E
Site 65
S522
A
D
Q
K
E
G
V
S
G
C
V
T
P
T
E
Site 66
S533
T
P
T
E
S
L
A
S
L
C
T
T
Q
S
E
Site 67
S539
A
S
L
C
T
T
Q
S
E
I
T
D
L
S
S
Site 68
S545
Q
S
E
I
T
D
L
S
S
A
S
C
L
R
G
Site 69
S546
S
E
I
T
D
L
S
S
A
S
C
L
R
G
F
Site 70
T569
K
P
L
E
G
S
Q
T
L
Y
H
W
Q
Q
L
Site 71
Y571
L
E
G
S
Q
T
L
Y
H
W
Q
Q
L
A
Q
Site 72
T593
D
P
R
P
G
V
I
T
K
G
F
T
Q
L
P
Site 73
Y605
Q
L
P
G
D
A
I
Y
H
I
S
D
L
E
E
Site 74
T619
E
D
E
E
E
G
I
T
F
Q
V
Q
Q
P
L
Site 75
S633
L
E
V
E
E
K
L
S
T
S
K
P
V
T
G
Site 76
T634
E
V
E
E
K
L
S
T
S
K
P
V
T
G
I
Site 77
S635
V
E
E
K
L
S
T
S
K
P
V
T
G
I
F
Site 78
S665
A
N
P
G
K
C
L
S
C
T
N
S
T
F
T
Site 79
T667
P
G
K
C
L
S
C
T
N
S
T
F
T
F
T
Site 80
T674
T
N
S
T
F
T
F
T
T
C
R
I
L
H
P
Site 81
T675
N
S
T
F
T
F
T
T
C
R
I
L
H
P
S
Site 82
S682
T
C
R
I
L
H
P
S
D
I
T
Q
V
T
P
Site 83
T685
I
L
H
P
S
D
I
T
Q
V
T
P
S
S
G
Site 84
T688
P
S
D
I
T
Q
V
T
P
S
S
G
F
P
S
Site 85
S695
T
P
S
S
G
F
P
S
L
S
C
G
S
S
G
Site 86
S697
S
S
G
F
P
S
L
S
C
G
S
S
G
S
S
Site 87
S700
F
P
S
L
S
C
G
S
S
G
S
S
S
S
N
Site 88
S701
P
S
L
S
C
G
S
S
G
S
S
S
S
N
T
Site 89
S703
L
S
C
G
S
S
G
S
S
S
S
N
T
A
V
Site 90
S704
S
C
G
S
S
G
S
S
S
S
N
T
A
V
N
Site 91
S705
C
G
S
S
G
S
S
S
S
N
T
A
V
N
S
Site 92
S706
G
S
S
G
S
S
S
S
N
T
A
V
N
S
P
Site 93
T708
S
G
S
S
S
S
N
T
A
V
N
S
P
A
L
Site 94
S712
S
S
N
T
A
V
N
S
P
A
L
S
Y
R
L
Site 95
S716
A
V
N
S
P
A
L
S
Y
R
L
S
I
G
E
Site 96
S720
P
A
L
S
Y
R
L
S
I
G
E
S
I
T
N
Site 97
S724
Y
R
L
S
I
G
E
S
I
T
N
R
R
D
S
Site 98
T726
L
S
I
G
E
S
I
T
N
R
R
D
S
T
T
Site 99
S731
S
I
T
N
R
R
D
S
T
T
T
F
S
S
T
Site 100
T732
I
T
N
R
R
D
S
T
T
T
F
S
S
T
M
Site 101
T733
T
N
R
R
D
S
T
T
T
F
S
S
T
M
S
Site 102
T734
N
R
R
D
S
T
T
T
F
S
S
T
M
S
L
Site 103
S736
R
D
S
T
T
T
F
S
S
T
M
S
L
A
K
Site 104
S737
D
S
T
T
T
F
S
S
T
M
S
L
A
K
L
Site 105
S740
T
T
F
S
S
T
M
S
L
A
K
L
L
Q
E
Site 106
S751
L
L
Q
E
R
G
I
S
A
K
V
Y
H
S
P
Site 107
Y755
R
G
I
S
A
K
V
Y
H
S
P
I
S
E
N
Site 108
S757
I
S
A
K
V
Y
H
S
P
I
S
E
N
P
L
Site 109
S760
K
V
Y
H
S
P
I
S
E
N
P
L
Q
P
L
Site 110
S770
P
L
Q
P
L
P
K
S
L
A
I
P
S
T
P
Site 111
S775
P
K
S
L
A
I
P
S
T
P
P
N
S
P
S
Site 112
T776
K
S
L
A
I
P
S
T
P
P
N
S
P
S
H
Site 113
S780
I
P
S
T
P
P
N
S
P
S
H
S
P
C
P
Site 114
S782
S
T
P
P
N
S
P
S
H
S
P
C
P
S
P
Site 115
S784
P
P
N
S
P
S
H
S
P
C
P
S
P
L
P
Site 116
S788
P
S
H
S
P
C
P
S
P
L
P
F
E
P
R
Site 117
S799
F
E
P
R
V
H
L
S
E
N
F
L
A
S
R
Site 118
S821
E
M
Y
G
L
R
P
S
R
N
P
P
D
V
G
Site 119
S870
I
G
P
Q
K
P
D
S
A
V
Y
L
N
S
G
Site 120
Y873
Q
K
P
D
S
A
V
Y
L
N
S
G
S
S
L
Site 121
S879
V
Y
L
N
S
G
S
S
L
L
G
G
L
R
R
Site 122
S889
G
G
L
R
R
N
Q
S
L
P
V
I
M
G
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation