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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIF1B
Full Name:
Kinesin-like protein KIF1B
Alias:
Klp
Type:
Motor protein; Microtubule binding protein
Mass (Da):
204476
Number AA:
1816
UniProt ID:
O60333
International Prot ID:
IPI00029011
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030659
GO:0005874
GO:0005875
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
GO:0019894
PhosphoSite+
KinaseNET
Biological Process:
GO:0008089
GO:0007270
GO:0007274
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
V
R
V
R
P
F
N
S
R
E
T
S
K
E
S
Site 2
T20
R
P
F
N
S
R
E
T
S
K
E
S
K
C
I
Site 3
S21
P
F
N
S
R
E
T
S
K
E
S
K
C
I
I
Site 4
S36
Q
M
Q
G
N
S
T
S
I
I
N
P
K
N
P
Site 5
S49
N
P
K
E
A
P
K
S
F
S
F
D
Y
S
Y
Site 6
S51
K
E
A
P
K
S
F
S
F
D
Y
S
Y
W
S
Site 7
Y54
P
K
S
F
S
F
D
Y
S
Y
W
S
H
T
S
Site 8
S55
K
S
F
S
F
D
Y
S
Y
W
S
H
T
S
P
Site 9
Y56
S
F
S
F
D
Y
S
Y
W
S
H
T
S
P
E
Site 10
S58
S
F
D
Y
S
Y
W
S
H
T
S
P
E
D
P
Site 11
T60
D
Y
S
Y
W
S
H
T
S
P
E
D
P
C
F
Site 12
Y74
F
A
S
Q
N
R
V
Y
N
D
I
G
K
E
M
Site 13
S104
G
Q
T
G
A
G
K
S
Y
T
M
M
G
K
Q
Site 14
Y105
Q
T
G
A
G
K
S
Y
T
M
M
G
K
Q
E
Site 15
T106
T
G
A
G
K
S
Y
T
M
M
G
K
Q
E
E
Site 16
S114
M
M
G
K
Q
E
E
S
Q
A
G
I
I
P
Q
Site 17
Y140
N
C
N
E
E
M
S
Y
S
V
E
V
S
Y
M
Site 18
Y146
S
Y
S
V
E
V
S
Y
M
E
I
Y
C
E
R
Site 19
Y150
E
V
S
Y
M
E
I
Y
C
E
R
V
R
D
L
Site 20
Y177
E
H
P
L
L
G
P
Y
V
E
D
L
S
K
L
Site 21
S182
G
P
Y
V
E
D
L
S
K
L
A
V
T
S
Y
Site 22
T204
D
A
G
N
K
A
R
T
V
A
A
T
N
M
N
Site 23
T208
K
A
R
T
V
A
A
T
N
M
N
E
T
S
S
Site 24
T213
A
A
T
N
M
N
E
T
S
S
R
S
H
A
V
Site 25
S214
A
T
N
M
N
E
T
S
S
R
S
H
A
V
F
Site 26
S217
M
N
E
T
S
S
R
S
H
A
V
F
T
I
V
Site 27
S237
H
D
N
E
T
N
L
S
T
E
K
V
S
K
I
Site 28
S252
S
L
V
D
L
A
G
S
E
R
A
D
S
T
G
Site 29
S257
A
G
S
E
R
A
D
S
T
G
A
K
G
T
R
Site 30
T258
G
S
E
R
A
D
S
T
G
A
K
G
T
R
L
Site 31
S274
E
G
A
N
I
N
K
S
L
T
T
L
G
K
V
Site 32
S293
A
E
V
D
N
C
T
S
K
S
K
K
K
K
K
Site 33
S295
V
D
N
C
T
S
K
S
K
K
K
K
K
T
D
Site 34
T301
K
S
K
K
K
K
K
T
D
F
I
P
Y
R
D
Site 35
T312
P
Y
R
D
S
V
L
T
W
L
L
R
E
N
L
Site 36
Y338
L
S
P
A
D
I
N
Y
D
E
T
L
S
T
L
Site 37
T341
A
D
I
N
Y
D
E
T
L
S
T
L
R
Y
A
Site 38
T344
N
Y
D
E
T
L
S
T
L
R
Y
A
D
R
A
Site 39
Y347
E
T
L
S
T
L
R
Y
A
D
R
A
K
Q
I
Site 40
Y401
I
D
P
L
I
D
D
Y
S
G
S
G
S
K
Y
Site 41
S402
D
P
L
I
D
D
Y
S
G
S
G
S
K
Y
L
Site 42
S404
L
I
D
D
Y
S
G
S
G
S
K
Y
L
K
D
Site 43
S406
D
D
Y
S
G
S
G
S
K
Y
L
K
D
F
Q
Site 44
Y408
Y
S
G
S
G
S
K
Y
L
K
D
F
Q
N
N
Site 45
Y419
F
Q
N
N
K
H
R
Y
L
L
A
S
E
N
Q
Site 46
S423
K
H
R
Y
L
L
A
S
E
N
Q
R
P
G
H
Site 47
S432
N
Q
R
P
G
H
F
S
T
A
S
M
G
S
L
Site 48
T433
Q
R
P
G
H
F
S
T
A
S
M
G
S
L
T
Site 49
S435
P
G
H
F
S
T
A
S
M
G
S
L
T
S
S
Site 50
S438
F
S
T
A
S
M
G
S
L
T
S
S
P
S
S
Site 51
T440
T
A
S
M
G
S
L
T
S
S
P
S
S
C
S
Site 52
S441
A
S
M
G
S
L
T
S
S
P
S
S
C
S
L
Site 53
S442
S
M
G
S
L
T
S
S
P
S
S
C
S
L
S
Site 54
S444
G
S
L
T
S
S
P
S
S
C
S
L
S
S
Q
Site 55
S445
S
L
T
S
S
P
S
S
C
S
L
S
S
Q
V
Site 56
S447
T
S
S
P
S
S
C
S
L
S
S
Q
V
G
L
Site 57
S449
S
P
S
S
C
S
L
S
S
Q
V
G
L
T
S
Site 58
S456
S
S
Q
V
G
L
T
S
V
T
S
I
Q
E
R
Site 59
S466
S
I
Q
E
R
I
M
S
T
P
G
G
E
E
A
Site 60
T467
I
Q
E
R
I
M
S
T
P
G
G
E
E
A
I
Site 61
T490
I
I
A
E
L
N
E
T
W
E
E
K
L
R
K
Site 62
T498
W
E
E
K
L
R
K
T
E
A
I
R
M
E
R
Site 63
T522
A
I
R
E
D
G
G
T
L
G
V
F
S
P
K
Site 64
S527
G
G
T
L
G
V
F
S
P
K
K
T
P
H
L
Site 65
T531
G
V
F
S
P
K
K
T
P
H
L
V
N
L
N
Site 66
Y550
M
S
E
C
L
L
Y
Y
I
K
D
G
I
T
R
Site 67
S585
E
E
H
C
I
F
R
S
E
R
S
N
S
G
E
Site 68
S590
F
R
S
E
R
S
N
S
G
E
V
I
V
T
L
Site 69
T596
N
S
G
E
V
I
V
T
L
E
P
C
E
R
S
Site 70
T605
E
P
C
E
R
S
E
T
Y
V
N
G
K
R
V
Site 71
Y606
P
C
E
R
S
E
T
Y
V
N
G
K
R
V
S
Site 72
S613
Y
V
N
G
K
R
V
S
Q
P
V
Q
L
R
S
Site 73
S620
S
Q
P
V
Q
L
R
S
G
N
R
I
I
M
G
Site 74
T647
A
R
A
E
R
E
K
T
P
S
A
E
T
P
S
Site 75
S649
A
E
R
E
K
T
P
S
A
E
T
P
S
E
P
Site 76
T652
E
K
T
P
S
A
E
T
P
S
E
P
V
D
W
Site 77
S654
T
P
S
A
E
T
P
S
E
P
V
D
W
T
F
Site 78
T660
P
S
E
P
V
D
W
T
F
A
Q
R
E
L
L
Site 79
Y707
L
E
Q
Q
R
L
D
Y
E
S
K
L
Q
A
L
Site 80
S709
Q
Q
R
L
D
Y
E
S
K
L
Q
A
L
Q
K
Site 81
S722
Q
K
Q
V
E
T
R
S
L
A
A
E
T
T
E
Site 82
T740
E
E
E
E
V
P
W
T
Q
H
E
F
E
L
A
Site 83
T760
K
W
K
S
H
Q
F
T
S
L
R
D
L
L
W
Site 84
S780
L
K
E
A
N
A
I
S
V
E
L
K
K
K
V
Site 85
T809
L
P
P
E
L
L
P
T
E
M
E
K
T
H
E
Site 86
T814
L
P
T
E
M
E
K
T
H
E
D
R
P
F
P
Site 87
T823
E
D
R
P
F
P
R
T
V
V
A
V
E
V
Q
Site 88
T837
Q
D
L
K
N
G
A
T
H
Y
W
S
L
E
K
Site 89
Y839
L
K
N
G
A
T
H
Y
W
S
L
E
K
L
K
Site 90
S841
N
G
A
T
H
Y
W
S
L
E
K
L
K
Q
R
Site 91
Y856
L
D
L
M
R
E
M
Y
D
R
A
G
E
M
A
Site 92
S865
R
A
G
E
M
A
S
S
A
Q
D
E
S
E
T
Site 93
S870
A
S
S
A
Q
D
E
S
E
T
T
V
T
G
S
Site 94
T873
A
Q
D
E
S
E
T
T
V
T
G
S
D
P
F
Site 95
T875
D
E
S
E
T
T
V
T
G
S
D
P
F
Y
D
Site 96
S877
S
E
T
T
V
T
G
S
D
P
F
Y
D
R
F
Site 97
Y881
V
T
G
S
D
P
F
Y
D
R
F
H
W
F
K
Site 98
T908
N
E
R
L
A
D
R
T
P
S
P
T
F
S
T
Site 99
S910
R
L
A
D
R
T
P
S
P
T
F
S
T
A
D
Site 100
T912
A
D
R
T
P
S
P
T
F
S
T
A
D
S
D
Site 101
S914
R
T
P
S
P
T
F
S
T
A
D
S
D
I
T
Site 102
S918
P
T
F
S
T
A
D
S
D
I
T
E
L
A
D
Site 103
S945
A
F
V
D
D
A
G
S
D
A
G
T
E
E
G
Site 104
T949
D
A
G
S
D
A
G
T
E
E
G
S
D
L
F
Site 105
S953
D
A
G
T
E
E
G
S
D
L
F
S
D
G
H
Site 106
S957
E
E
G
S
D
L
F
S
D
G
H
D
P
F
Y
Site 107
Y964
S
D
G
H
D
P
F
Y
D
R
S
P
W
F
I
Site 108
S997
I
H
R
V
A
I
V
S
E
K
G
E
V
R
G
Site 109
Y1022
A
D
E
E
A
P
D
Y
G
S
G
I
R
Q
S
Site 110
S1024
E
E
A
P
D
Y
G
S
G
I
R
Q
S
G
T
Site 111
S1029
Y
G
S
G
I
R
Q
S
G
T
A
K
I
S
F
Site 112
T1031
S
G
I
R
Q
S
G
T
A
K
I
S
F
D
N
Site 113
S1035
Q
S
G
T
A
K
I
S
F
D
N
E
Y
F
N
Site 114
Y1040
K
I
S
F
D
N
E
Y
F
N
Q
S
D
F
S
Site 115
S1044
D
N
E
Y
F
N
Q
S
D
F
S
S
V
A
M
Site 116
S1047
Y
F
N
Q
S
D
F
S
S
V
A
M
T
R
S
Site 117
S1048
F
N
Q
S
D
F
S
S
V
A
M
T
R
S
G
Site 118
T1052
D
F
S
S
V
A
M
T
R
S
G
L
S
L
E
Site 119
S1054
S
S
V
A
M
T
R
S
G
L
S
L
E
E
L
Site 120
S1057
A
M
T
R
S
G
L
S
L
E
E
L
R
I
V
Site 121
S1071
V
E
G
Q
G
Q
S
S
E
V
I
T
P
P
E
Site 122
T1075
G
Q
S
S
E
V
I
T
P
P
E
E
I
S
R
Site 123
S1090
I
N
D
L
D
L
K
S
S
T
L
L
D
G
K
Site 124
T1152
R
H
D
E
A
F
S
T
E
P
L
K
N
N
G
Site 125
S1162
L
K
N
N
G
R
G
S
P
L
A
F
Y
H
V
Site 126
Y1197
V
F
E
V
F
G
H
Y
Q
Q
H
P
L
H
L
Site 127
S1211
L
Q
G
Q
E
L
N
S
P
P
Q
P
C
R
R
Site 128
S1227
F
P
P
P
M
P
L
S
K
P
V
P
A
T
K
Site 129
T1237
V
P
A
T
K
L
N
T
M
S
K
T
S
L
G
Site 130
S1239
A
T
K
L
N
T
M
S
K
T
S
L
G
Q
S
Site 131
T1241
K
L
N
T
M
S
K
T
S
L
G
Q
S
M
S
Site 132
S1242
L
N
T
M
S
K
T
S
L
G
Q
S
M
S
K
Site 133
S1246
S
K
T
S
L
G
Q
S
M
S
K
Y
D
L
L
Site 134
S1248
T
S
L
G
Q
S
M
S
K
Y
D
L
L
V
W
Site 135
Y1250
L
G
Q
S
M
S
K
Y
D
L
L
V
W
F
E
Site 136
T1264
E
I
S
E
L
E
P
T
G
E
Y
I
P
A
V
Site 137
T1295
Q
G
I
Q
R
R
I
T
V
T
I
I
H
E
K
Site 138
T1297
I
Q
R
R
I
T
V
T
I
I
H
E
K
G
S
Site 139
Y1343
L
N
I
I
S
A
K
Y
L
K
S
S
H
N
S
Site 140
S1346
I
S
A
K
Y
L
K
S
S
H
N
S
S
R
T
Site 141
S1347
S
A
K
Y
L
K
S
S
H
N
S
S
R
T
F
Site 142
S1350
Y
L
K
S
S
H
N
S
S
R
T
F
Y
R
F
Site 143
S1351
L
K
S
S
H
N
S
S
R
T
F
Y
R
F
E
Site 144
T1353
S
S
H
N
S
S
R
T
F
Y
R
F
E
A
V
Site 145
Y1355
H
N
S
S
R
T
F
Y
R
F
E
A
V
W
D
Site 146
S1363
R
F
E
A
V
W
D
S
S
L
H
N
S
L
L
Site 147
S1368
W
D
S
S
L
H
N
S
L
L
L
N
R
V
T
Site 148
T1375
S
L
L
L
N
R
V
T
P
Y
G
E
K
I
Y
Site 149
Y1382
T
P
Y
G
E
K
I
Y
M
T
L
S
A
Y
L
Site 150
S1386
E
K
I
Y
M
T
L
S
A
Y
L
E
L
D
H
Site 151
Y1409
K
D
V
C
M
V
F
Y
S
R
D
A
K
I
S
Site 152
S1416
Y
S
R
D
A
K
I
S
P
P
R
S
L
R
S
Site 153
S1420
A
K
I
S
P
P
R
S
L
R
S
L
F
G
S
Site 154
S1423
S
P
P
R
S
L
R
S
L
F
G
S
G
Y
S
Site 155
S1427
S
L
R
S
L
F
G
S
G
Y
S
K
S
P
D
Site 156
Y1429
R
S
L
F
G
S
G
Y
S
K
S
P
D
S
N
Site 157
S1430
S
L
F
G
S
G
Y
S
K
S
P
D
S
N
R
Site 158
S1432
F
G
S
G
Y
S
K
S
P
D
S
N
R
V
T
Site 159
S1435
G
Y
S
K
S
P
D
S
N
R
V
T
G
I
Y
Site 160
T1439
S
P
D
S
N
R
V
T
G
I
Y
E
L
S
L
Site 161
Y1442
S
N
R
V
T
G
I
Y
E
L
S
L
C
K
M
Site 162
S1450
E
L
S
L
C
K
M
S
D
T
G
S
P
G
M
Site 163
T1452
S
L
C
K
M
S
D
T
G
S
P
G
M
Q
R
Site 164
S1454
C
K
M
S
D
T
G
S
P
G
M
Q
R
R
R
Site 165
T1467
R
R
R
K
I
L
D
T
S
V
A
Y
V
R
G
Site 166
S1468
R
R
K
I
L
D
T
S
V
A
Y
V
R
G
E
Site 167
Y1471
I
L
D
T
S
V
A
Y
V
R
G
E
E
N
L
Site 168
S1487
G
W
R
P
R
G
D
S
L
I
L
E
H
Q
W
Site 169
T1508
L
L
H
E
V
E
K
T
R
H
F
L
L
L
R
Site 170
S1521
L
R
E
R
L
G
D
S
I
P
K
S
L
S
D
Site 171
S1525
L
G
D
S
I
P
K
S
L
S
D
S
L
S
P
Site 172
S1527
D
S
I
P
K
S
L
S
D
S
L
S
P
S
L
Site 173
S1529
I
P
K
S
L
S
D
S
L
S
P
S
L
S
S
Site 174
S1531
K
S
L
S
D
S
L
S
P
S
L
S
S
G
T
Site 175
S1533
L
S
D
S
L
S
P
S
L
S
S
G
T
L
S
Site 176
S1535
D
S
L
S
P
S
L
S
S
G
T
L
S
T
S
Site 177
S1536
S
L
S
P
S
L
S
S
G
T
L
S
T
S
T
Site 178
T1538
S
P
S
L
S
S
G
T
L
S
T
S
T
S
I
Site 179
S1540
S
L
S
S
G
T
L
S
T
S
T
S
I
S
S
Site 180
T1541
L
S
S
G
T
L
S
T
S
T
S
I
S
S
Q
Site 181
S1542
S
S
G
T
L
S
T
S
T
S
I
S
S
Q
I
Site 182
T1543
S
G
T
L
S
T
S
T
S
I
S
S
Q
I
S
Site 183
S1544
G
T
L
S
T
S
T
S
I
S
S
Q
I
S
T
Site 184
S1546
L
S
T
S
T
S
I
S
S
Q
I
S
T
T
T
Site 185
S1547
S
T
S
T
S
I
S
S
Q
I
S
T
T
T
F
Site 186
S1550
T
S
I
S
S
Q
I
S
T
T
T
F
E
S
A
Site 187
T1553
S
S
Q
I
S
T
T
T
F
E
S
A
I
T
P
Site 188
S1556
I
S
T
T
T
F
E
S
A
I
T
P
S
E
S
Site 189
T1559
T
T
F
E
S
A
I
T
P
S
E
S
S
G
Y
Site 190
S1561
F
E
S
A
I
T
P
S
E
S
S
G
Y
D
S
Site 191
S1563
S
A
I
T
P
S
E
S
S
G
Y
D
S
G
D
Site 192
S1564
A
I
T
P
S
E
S
S
G
Y
D
S
G
D
I
Site 193
Y1566
T
P
S
E
S
S
G
Y
D
S
G
D
I
E
S
Site 194
S1568
S
E
S
S
G
Y
D
S
G
D
I
E
S
L
V
Site 195
S1573
Y
D
S
G
D
I
E
S
L
V
D
R
E
K
E
Site 196
T1592
C
L
Q
L
L
T
H
T
F
N
R
E
F
S
Q
Site 197
S1598
H
T
F
N
R
E
F
S
Q
V
H
G
S
V
S
Site 198
S1603
E
F
S
Q
V
H
G
S
V
S
D
C
K
L
S
Site 199
S1605
S
Q
V
H
G
S
V
S
D
C
K
L
S
D
I
Site 200
S1610
S
V
S
D
C
K
L
S
D
I
S
P
I
G
R
Site 201
S1613
D
C
K
L
S
D
I
S
P
I
G
R
D
P
S
Site 202
S1620
S
P
I
G
R
D
P
S
E
S
S
F
S
S
A
Site 203
S1622
I
G
R
D
P
S
E
S
S
F
S
S
A
T
L
Site 204
S1623
G
R
D
P
S
E
S
S
F
S
S
A
T
L
T
Site 205
S1625
D
P
S
E
S
S
F
S
S
A
T
L
T
P
S
Site 206
S1626
P
S
E
S
S
F
S
S
A
T
L
T
P
S
S
Site 207
T1628
E
S
S
F
S
S
A
T
L
T
P
S
S
T
C
Site 208
T1630
S
F
S
S
A
T
L
T
P
S
S
T
C
P
S
Site 209
S1632
S
S
A
T
L
T
P
S
S
T
C
P
S
L
V
Site 210
S1637
T
P
S
S
T
C
P
S
L
V
D
S
R
S
N
Site 211
S1641
T
C
P
S
L
V
D
S
R
S
N
S
L
D
Q
Site 212
S1643
P
S
L
V
D
S
R
S
N
S
L
D
Q
K
T
Site 213
S1645
L
V
D
S
R
S
N
S
L
D
Q
K
T
P
E
Site 214
T1650
S
N
S
L
D
Q
K
T
P
E
A
N
S
R
A
Site 215
S1655
Q
K
T
P
E
A
N
S
R
A
S
S
P
C
P
Site 216
S1658
P
E
A
N
S
R
A
S
S
P
C
P
E
F
E
Site 217
S1659
E
A
N
S
R
A
S
S
P
C
P
E
F
E
Q
Site 218
T1675
Q
I
V
P
A
V
E
T
P
Y
L
A
R
A
G
Site 219
Y1677
V
P
A
V
E
T
P
Y
L
A
R
A
G
K
N
Site 220
S1699
D
I
E
E
I
R
P
S
S
V
V
S
K
K
G
Site 221
S1700
I
E
E
I
R
P
S
S
V
V
S
K
K
G
Y
Site 222
S1703
I
R
P
S
S
V
V
S
K
K
G
Y
L
H
F
Site 223
Y1707
S
V
V
S
K
K
G
Y
L
H
F
K
E
P
L
Site 224
Y1715
L
H
F
K
E
P
L
Y
S
N
W
A
K
H
F
Site 225
Y1733
R
R
P
Y
V
F
I
Y
N
S
D
K
D
P
V
Site 226
S1735
P
Y
V
F
I
Y
N
S
D
K
D
P
V
E
R
Site 227
S1748
E
R
G
I
I
N
L
S
T
A
Q
V
E
Y
S
Site 228
S1755
S
T
A
Q
V
E
Y
S
E
D
Q
Q
A
M
V
Site 229
T1764
D
Q
Q
A
M
V
K
T
P
N
T
F
A
V
C
Site 230
Y1792
K
D
M
N
D
W
L
Y
A
F
N
P
L
L
A
Site 231
T1801
F
N
P
L
L
A
G
T
I
R
S
K
L
S
R
Site 232
S1807
G
T
I
R
S
K
L
S
R
R
C
P
S
Q
S
Site 233
S1812
K
L
S
R
R
C
P
S
Q
S
K
Y
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation