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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GDF9
Full Name:
Growth/differentiation factor 9
Alias:
Type:
Mass (Da):
51444
Number AA:
454
UniProt ID:
O60383
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
G
E
A
Q
I
A
A
S
A
E
L
E
S
G
A
Site 2
S48
E
S
G
A
M
P
W
S
L
L
Q
H
I
D
E
Site 3
S76
L
S
V
G
R
G
G
S
P
R
L
Q
P
D
S
Site 4
S83
S
P
R
L
Q
P
D
S
R
A
L
H
Y
M
K
Site 5
S105
T
K
E
G
I
P
K
S
N
R
S
H
L
Y
N
Site 6
Y111
K
S
N
R
S
H
L
Y
N
T
V
R
L
F
T
Site 7
T113
N
R
S
H
L
Y
N
T
V
R
L
F
T
P
C
Site 8
T118
Y
N
T
V
R
L
F
T
P
C
T
R
H
K
Q
Site 9
T121
V
R
L
F
T
P
C
T
R
H
K
Q
A
P
G
Site 10
T149
F
N
L
D
R
I
T
T
V
E
H
L
L
K
S
Site 11
S156
T
V
E
H
L
L
K
S
V
L
L
Y
N
I
N
Site 12
S167
Y
N
I
N
N
S
V
S
F
S
S
A
V
K
C
Site 13
S170
N
N
S
V
S
F
S
S
A
V
K
C
V
C
N
Site 14
S185
L
M
I
K
E
P
K
S
S
S
R
T
L
G
R
Site 15
S186
M
I
K
E
P
K
S
S
S
R
T
L
G
R
A
Site 16
T189
E
P
K
S
S
S
R
T
L
G
R
A
P
Y
S
Site 17
Y195
R
T
L
G
R
A
P
Y
S
F
T
F
N
S
Q
Site 18
S196
T
L
G
R
A
P
Y
S
F
T
F
N
S
Q
F
Site 19
T198
G
R
A
P
Y
S
F
T
F
N
S
Q
F
E
F
Site 20
S201
P
Y
S
F
T
F
N
S
Q
F
E
F
G
K
K
Site 21
S226
L
L
Q
P
L
V
A
S
N
K
R
S
I
H
M
Site 22
S230
L
V
A
S
N
K
R
S
I
H
M
S
I
N
F
Site 23
T270
L
I
L
Y
L
N
D
T
S
A
Q
A
Y
H
S
Site 24
Y275
N
D
T
S
A
Q
A
Y
H
S
W
Y
S
L
H
Site 25
Y283
H
S
W
Y
S
L
H
Y
K
R
R
P
S
Q
G
Site 26
S288
L
H
Y
K
R
R
P
S
Q
G
P
D
Q
E
R
Site 27
S296
Q
G
P
D
Q
E
R
S
L
S
A
Y
P
V
G
Site 28
S298
P
D
Q
E
R
S
L
S
A
Y
P
V
G
E
E
Site 29
Y300
Q
E
R
S
L
S
A
Y
P
V
G
E
E
A
A
Site 30
S312
E
A
A
E
D
G
R
S
S
H
H
R
H
R
R
Site 31
S313
A
A
E
D
G
R
S
S
H
H
R
H
R
R
G
Site 32
T323
R
H
R
R
G
Q
E
T
V
S
S
E
L
K
K
Site 33
S325
R
R
G
Q
E
T
V
S
S
E
L
K
K
P
L
Site 34
S326
R
G
Q
E
T
V
S
S
E
L
K
K
P
L
G
Site 35
S336
K
K
P
L
G
P
A
S
F
N
L
S
E
Y
F
Site 36
S340
G
P
A
S
F
N
L
S
E
Y
F
R
Q
F
L
Site 37
Y342
A
S
F
N
L
S
E
Y
F
R
Q
F
L
L
P
Site 38
S361
E
L
H
D
F
R
L
S
F
S
Q
L
K
W
D
Site 39
Y381
P
H
R
Y
N
P
R
Y
C
K
G
D
C
P
R
Site 40
Y394
P
R
A
V
G
H
R
Y
G
S
P
V
H
T
M
Site 41
S396
A
V
G
H
R
Y
G
S
P
V
H
T
M
V
Q
Site 42
T400
R
Y
G
S
P
V
H
T
M
V
Q
N
I
I
Y
Site 43
Y407
T
M
V
Q
N
I
I
Y
E
K
L
D
S
S
V
Site 44
S412
I
I
Y
E
K
L
D
S
S
V
P
R
P
S
C
Site 45
S413
I
Y
E
K
L
D
S
S
V
P
R
P
S
C
V
Site 46
S418
D
S
S
V
P
R
P
S
C
V
P
A
K
Y
S
Site 47
S428
P
A
K
Y
S
P
L
S
V
L
T
I
E
P
D
Site 48
S437
L
T
I
E
P
D
G
S
I
A
Y
K
E
Y
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation